Ligand: MHR

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3BHUA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3BHUA P24941 1 298 298.0 MHR:60299 Type1 Active DFGin 6.786 14.752 BLAminus -134.75, 170.97 59.59, 89.97 -106.95, 20.16 283.64, 70.88 -60.21, -32.38 in-in in 8.351 Saltbr-in 2.647 HRD-in -76.05, -54.75 70.15, 15.56 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.89, 153.14 APE9-dihe-na 80.36, 131.09 APE8-dihe-in -55.87, 134.7 APE8-rot-in 300.34 APE67-dihe-in -60.91, -24.11 -43.0, -50.07 APE12-dist-in 13.226 APE11-dist-in 8.622 APE10-dist-in 7.792 APE9-dist-in 3.19 None TPO160 TPO160 XRAY 2.3 0.197 0.24 A 300 296 2 0 0 0 [[4, 286]] 1.0 3bhu CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3BHUC P24941 1 296 298.0 MHR:60299 Type1.5_Back Active DFGin 6.711 14.747 BLAminus -135.55, 171.6 58.78, 89.32 -103.71, 20.04 281.06, 67.57 -60.23, -27.81 in-in in 8.385 Saltbr-in 2.558 HRD-in -83.56, -56.59 72.77, 13.78 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -30.58, 137.53 APE9-dihe-na 72.29, 126.42 APE8-dihe-in -48.13, 131.39 APE8-rot-in 307.87 APE67-dihe-in -59.11, -18.02 -39.31, -52.67 APE12-dist-in 12.706 APE11-dist-in 9.599 APE10-dist-in 7.189 APE9-dist-in 3.322 None TPO160 TPO160 XRAY 2.3 0.197 0.24 C 300 270 26 0 0 0 [[4, 286]] 1.0 3bhu CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: MHR

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 3BHUA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 3BHUA P24941 1 298 298.0 MHR:60299 Type1 Active DFGin 6.786 14.752 BLAminus -134.75, 170.97 59.59, 89.97 -106.95, 20.16 283.64, 70.88 -60.21, -32.38 in-in in 8.351 Saltbr-in 2.647 HRD-in -76.05, -54.75 70.15, 15.56 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.89, 153.14 APE9-dihe-na 80.36, 131.09 APE8-dihe-in -55.87, 134.7 APE8-rot-in 300.34 APE67-dihe-in -60.91, -24.11 -43.0, -50.07 APE12-dist-in 13.226 APE11-dist-in 8.622 APE10-dist-in 7.792 APE9-dist-in 3.19 None TPO160 TPO160 XRAY 2.3 0.197 0.24 A 300 296 2 0 0 0 [[4, 286]] 1.0 3bhu Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3BHUC P24941 1 296 298.0 MHR:60299 Type1.5_Back Active DFGin 6.711 14.747 BLAminus -135.55, 171.6 58.78, 89.32 -103.71, 20.04 281.06, 67.57 -60.23, -27.81 in-in in 8.385 Saltbr-in 2.558 HRD-in -83.56, -56.59 72.77, 13.78 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -30.58, 137.53 APE9-dihe-na 72.29, 126.42 APE8-dihe-in -48.13, 131.39 APE8-rot-in 307.87 APE67-dihe-in -59.11, -18.02 -39.31, -52.67 APE12-dist-in 12.706 APE11-dist-in 9.599 APE10-dist-in 7.189 APE9-dist-in 3.322 None TPO160 TPO160 XRAY 2.3 0.197 0.24 C 300 270 26 0 0 0 [[4, 286]] 1.0 3bhu Homo sapiens CMGC_CDK2_HUMAN CMGC 6.5e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: MHR

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name