Ligand: L66

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4GK2A
DFGin BLBminus 1 50.0% 5IA2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EPHA2 EPHA2_HUMAN 5IA2A P29317 598 888 976.0 L66:1001 Type1.5_Back Inactive DFGin 6.0332 14.2577 BLBminus -134.41, -178.14 76.73, 84.08 -119.06, 159.2 303.5, 118.54 144.3, -174.17 in-out in 8.4002 Saltbr-out 3.6911 HRD-in -77.24, -46.91 75.8, -16.93 out-out-in SNCooi out-in ActLoopNT-out 10.4627 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -104.98, 106.86 APE9-dihe-in -142.72, 149.22 APE8-dihe-in -83.94, 92.51 APE8-rot-na 31.71 APE67-dihe-in -79.44, -1.75 -55.95, -46.88 APE12-dist-na 17.0507 APE11-dist-na 14.007 APE10-dist-na 12.2737 APE9-dist-in 6.581 None None None XRAY 1.619 0.164 0.199 A 306.0 287.0 4 31 31 0 [[613, 873]] 1.0 5ia2 TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 4GK2A P29320 609 903 983.0 L66:1001 Type1.5_Back None DFGin 5.3932 14.3449 BLAminus -141.54, -172.14 65.23, 79.03 -100.69, 30.27 304.12, 98.46 -69.06, -39.74 in-in in 7.9562 Saltbr-in 2.5111 HRD-in -70.13, -49.29 72.76, -10.27 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 71.91 APE8-rot-na 28.95 APE67-dihe-in -60.83, -25.11 -56.53, -45.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.195 0.193 0.236 A 361.0 265.0 19 31 12 19 [[621, 880]] 1.0 4gk2 TYR_EPHA3_HUMAN TYR 9.8e-111 375.2 2.0 261.0 260.0 763 764 765 767 769 653 670 674 743 745 744 746.0 806 794 789 788 787 786 785 784 783 700 Ephrin type-A receptor 3

Ligand: L66

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 4GK2A
DFGin BLBminus 1 50.0% 5IA2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EPHA2 EPHA2_HUMAN 5IA2A P29317 598 888 976.0 L66:1001 Type1.5_Back Inactive DFGin 6.0332 14.2577 BLBminus -134.41, -178.14 76.73, 84.08 -119.06, 159.2 303.5, 118.54 144.3, -174.17 in-out in 8.4002 Saltbr-out 3.6911 HRD-in -77.24, -46.91 75.8, -16.93 out-out-in SNCooi out-in ActLoopNT-out 10.4627 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -104.98, 106.86 APE9-dihe-in -142.72, 149.22 APE8-dihe-in -83.94, 92.51 APE8-rot-na 31.71 APE67-dihe-in -79.44, -1.75 -55.95, -46.88 APE12-dist-na 17.0507 APE11-dist-na 14.007 APE10-dist-na 12.2737 APE9-dist-in 6.581 None None None XRAY 1.619 0.164 0.199 A 306.0 287.0 4 31 31 0 [[613, 873]] 1.0 5ia2 Homo sapiens TYR_EPHA2_HUMAN TYR 5.5e-108 366.1 2.0 261.0 260.0 756 757 758 760 762 646 663 667 736 738 737 739.0 799 787 782 781 780 779 778 777 776 693 Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 4GK2A P29320 609 903 983.0 L66:1001 Type1.5_Back None DFGin 5.3932 14.3449 BLAminus -141.54, -172.14 65.23, 79.03 -100.69, 30.27 304.12, 98.46 -69.06, -39.74 in-in in 7.9562 Saltbr-in 2.5111 HRD-in -70.13, -49.29 72.76, -10.27 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 71.91 APE8-rot-na 28.95 APE67-dihe-in -60.83, -25.11 -56.53, -45.51 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 2.195 0.193 0.236 A 361.0 265.0 19 31 12 19 [[621, 880]] 1.0 4gk2 Homo sapiens TYR_EPHA3_HUMAN TYR 9.8e-111 375.2 2.0 261.0 260.0 763 764 765 767 769 653 670 674 743 745 744 746.0 806 794 789 788 787 786 785 784 783 700 Ephrin type-A receptor 3

Ligand: L66

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name