Ligand: INR

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1E9HA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1E9HA P24941 1 296 298.0 INR:61298 Type1 Active DFGin 6.4562 15.1591 BLAminus -132.15, -179.42 51.68, 79.15 -95.02, 38.05 281.94, 68.75 -76.13, -20.19 in-in in 9.0343 Saltbr-in 2.8676 HRD-in -74.58, -48.32 61.21, 19.86 in-in-in SNCiii in-in ActLoopNT-in 3.1021 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.15, 144.05 APE9-dihe-na 74.6, 131.04 APE8-dihe-in -55.94, 131.78 APE8-rot-in 296.32 APE67-dihe-in -63.26, -22.84 -39.36, -49.77 APE12-dist-in 12.8804 APE11-dist-in 10.1261 APE10-dist-in 7.3056 APE9-dist-in 3.295 None TPO160 TPO160 XRAY 2.5 0.225 0.273 A 297.0 296.0 0 28 28 0 [[4, 286]] 1.0 1e9h CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1E9HC P24941 1 296 298.0 INR:61298 Type1 Active DFGin 6.1872 14.8163 BLAminus -143.02, -176.13 46.31, 80.97 -97.02, 27.76 290.87, 59.63 -66.56, -7.89 in-in in 8.729 Saltbr-in 3.1594 HRD-in -83.98, -58.29 69.53, 16.91 in-in-in SNCiii in-in ActLoopNT-in 2.8627 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.56, 140.46 APE9-dihe-na 71.87, 130.47 APE8-dihe-in -59.96, 126.8 APE8-rot-in 308.14 APE67-dihe-in -42.57, -36.53 -26.81, -69.86 APE12-dist-in 12.7353 APE11-dist-in 9.9352 APE10-dist-in 7.4074 APE9-dist-in 3.3365 None TPO160 TPO160 XRAY 2.5 0.225 0.273 C 297.0 296.0 0 28 28 0 [[4, 286]] 1.0 1e9h CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: INR

Total number of chains: 4
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 1E9HA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1E9HA P24941 1 296 298.0 INR:61298 Type1 Active DFGin 6.4562 15.1591 BLAminus -132.15, -179.42 51.68, 79.15 -95.02, 38.05 281.94, 68.75 -76.13, -20.19 in-in in 9.0343 Saltbr-in 2.8676 HRD-in -74.58, -48.32 61.21, 19.86 in-in-in SNCiii in-in ActLoopNT-in 3.1021 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.15, 144.05 APE9-dihe-na 74.6, 131.04 APE8-dihe-in -55.94, 131.78 APE8-rot-in 296.32 APE67-dihe-in -63.26, -22.84 -39.36, -49.77 APE12-dist-in 12.8804 APE11-dist-in 10.1261 APE10-dist-in 7.3056 APE9-dist-in 3.295 None TPO160 TPO160 XRAY 2.5 0.225 0.273 A 297.0 296.0 0 28 28 0 [[4, 286]] 1.0 1e9h Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1E9HC P24941 1 296 298.0 INR:61298 Type1 Active DFGin 6.1872 14.8163 BLAminus -143.02, -176.13 46.31, 80.97 -97.02, 27.76 290.87, 59.63 -66.56, -7.89 in-in in 8.729 Saltbr-in 3.1594 HRD-in -83.98, -58.29 69.53, 16.91 in-in-in SNCiii in-in ActLoopNT-in 2.8627 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.56, 140.46 APE9-dihe-na 71.87, 130.47 APE8-dihe-in -59.96, 126.8 APE8-rot-in 308.14 APE67-dihe-in -42.57, -36.53 -26.81, -69.86 APE12-dist-in 12.7353 APE11-dist-in 9.9352 APE10-dist-in 7.4074 APE9-dist-in 3.3365 None TPO160 TPO160 XRAY 2.5 0.225 0.273 C 297.0 296.0 0 28 28 0 [[4, 286]] 1.0 1e9h Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CRK2 CDK2H_PLAFK 1V0OA Q07785 3 287 288.0 INR:2638 Type1 Inactive DFGin 6.8971 14.8192 BLAminus -130.45, 176.77 60.74, 73.08 -90.85, 27.78 290.19, 84.14 -73.54, -12.17 in-in in 9.483 Saltbr-in 2.8747 HRD-in -85.76, -50.51 74.23, -2.01 in-in-out SNCiio in-out ActLoopNT-in 2.8484 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -73.57, -58.84 APE9-dihe-na -68.69, 141.87 APE8-dihe-in -55.26, 163.27 APE8-rot-in 346.69 APE67-dihe-in -57.67, -30.3 -101.18, -24.26 APE12-dist-in 13.0143 APE11-dist-in 12.8641 APE10-dist-out 8.1859 APE9-dist-out 6.9246 None None None XRAY 1.9 0.233 0.282 A 288.0 277.0 8 28 28 0 [[4, 284]] 1.0 1v0o Plasmodium falciparum CMGC_CRK2_PLAFK CMGC 1.3e-82 284.5 1.0 301.0 301.0 142 143 144 146 148 32 50 54 122 124 123 125.0 183 170 165 164 163 162 161 160 159 80 Cyclin-dependent kinase 2 homolog
CMGC CRK2 CDK2H_PLAFK 1V0OB Q07785 3 287 288.0 INR:2638 Type1 Inactive DFGin 6.9087 14.9982 BLAminus -124.66, -173.2 54.09, 80.05 -100.18, 21.26 288.74, 77.41 -55.94, -35.19 in-in in 9.6001 Saltbr-in 3.2105 HRD-in -70.2, -54.8 74.36, -4.91 in-in-out SNCiio in-out ActLoopNT-in 2.9268 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -122.08, 9.35 APE9-dihe-na -122.18, 158.82 APE8-dihe-in -82.32, 135.95 APE8-rot-in 292.34 APE67-dihe-in -63.55, -20.14 -100.79, -13.64 APE12-dist-in 13.2144 APE11-dist-in 12.8605 APE10-dist-out 9.7096 APE9-dist-out 8.3902 None None None XRAY 1.9 0.233 0.282 B 288.0 275.0 10 28 28 0 [[4, 284]] 1.0 1v0o Plasmodium falciparum CMGC_CRK2_PLAFK CMGC 1.3e-82 284.5 1.0 301.0 301.0 142 143 144 146 148 32 50 54 122 124 123 125.0 183 170 165 164 163 162 161 160 159 80 Cyclin-dependent kinase 2 homolog

Ligand: INR

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1V0OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CRK2 CDK2H_PLAFK 1V0OA Q07785 3 287 288.0 INR:2638 Type1 Inactive DFGin 6.8971 14.8192 BLAminus -130.45, 176.77 60.74, 73.08 -90.85, 27.78 290.19, 84.14 -73.54, -12.17 in-in in 9.483 Saltbr-in 2.8747 HRD-in -85.76, -50.51 74.23, -2.01 in-in-out SNCiio in-out ActLoopNT-in 2.8484 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -73.57, -58.84 APE9-dihe-na -68.69, 141.87 APE8-dihe-in -55.26, 163.27 APE8-rot-in 346.69 APE67-dihe-in -57.67, -30.3 -101.18, -24.26 APE12-dist-in 13.0143 APE11-dist-in 12.8641 APE10-dist-out 8.1859 APE9-dist-out 6.9246 None None None XRAY 1.9 0.233 0.282 A 288.0 277.0 8 28 28 0 [[4, 284]] 1.0 1v0o Plasmodium falciparum CMGC_CRK2_PLAFK CMGC 1.3e-82 284.5 1.0 301.0 301.0 142 143 144 146 148 32 50 54 122 124 123 125.0 183 170 165 164 163 162 161 160 159 80 Cyclin-dependent kinase 2 homolog
CMGC CRK2 CDK2H_PLAFK 1V0OB Q07785 3 287 288.0 INR:2638 Type1 Inactive DFGin 6.9087 14.9982 BLAminus -124.66, -173.2 54.09, 80.05 -100.18, 21.26 288.74, 77.41 -55.94, -35.19 in-in in 9.6001 Saltbr-in 3.2105 HRD-in -70.2, -54.8 74.36, -4.91 in-in-out SNCiio in-out ActLoopNT-in 2.9268 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -122.08, 9.35 APE9-dihe-na -122.18, 158.82 APE8-dihe-in -82.32, 135.95 APE8-rot-in 292.34 APE67-dihe-in -63.55, -20.14 -100.79, -13.64 APE12-dist-in 13.2144 APE11-dist-in 12.8605 APE10-dist-out 9.7096 APE9-dist-out 8.3902 None None None XRAY 1.9 0.233 0.282 B 288.0 275.0 10 28 28 0 [[4, 284]] 1.0 1v0o Plasmodium falciparum CMGC_CRK2_PLAFK CMGC 1.3e-82 284.5 1.0 301.0 301.0 142 143 144 146 148 32 50 54 122 124 123 125.0 183 170 165 164 163 162 161 160 159 80 Cyclin-dependent kinase 2 homolog