Ligand: IKD

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8Q1ZA
DFGin None 1 50.0% 9D6PA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK2 VRK2_HUMAN 8Q1ZA Q86Y07 15 330 508.0 IKD:401 Type1 Active DFGin 7.639 14.284 BLAminus DFGAsp-rot-in -121.18, 178.27 65.89, 75.15 190.5, -11.66 -84.6, 26.91 299.19, 79.94 -58.07, -32.45 in-in in 7.791 Saltbr-in 2.807 HRD-in -86.89, -55.74 82.47, 4.18 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.8, 160.18 APE9-dihe-na 103.61, -173.61 APE8-dihe-in -78.9, 112.93 APE8-rot-in 304.74 APE67-dihe-in -56.6, -35.59 -54.54, -39.51 APE12-dist-in 13.701 APE11-dist-in 13.766 APE10-dist-in 7.989 APE9-dist-in 4.571 None None None XRAY 1.85 0.203 0.251 A 324 311 5 0 0 0 [[29, 315]] 1.0 8q1z CK1_VRK2_HUMAN CK1 1.6e-103 351.6 1 261 261 185 186 187 189 191 61 73 77 163 165 164 166 232 220 215 214 213 212 211 210 209 122 Serine/threonine-protein kinase VRK2
CMGC MAPK14 MK14_HUMAN 9D6PA Q16539 5 353 360.0 A1IKD:60401 Type1 Inactive DFGin 4.165 14.29 None DFGAsp-rot-out -114.9917, 156.3089 64.0177, 34.1029 290.9979, -36.0041 -67.5205, 999.0 42.4914, 90.8481 -67.5205, 999.0 in-out in 9.994 Saltbr-out 3.889 HRD-in -73.2049, -53.4523 81.5844, -17.9664 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.781, -14.3674 999.0, 123.5057 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.13 0.213 0.244 A 346 335 11 0 0 11 [[24, 308]] 1.0 9d6p CMGC_MAPK14_HUMAN CMGC 2.5e-79 272.7 1 301 301 167 168 169 173 175 53 71 75 147 149 148 150 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: IKD

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8Q1ZA
DFGin None 1 50.0% 9D6PA
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK2 VRK2_HUMAN 8Q1ZA Q86Y07 15 330 508.0 IKD:401 Type1 Active DFGin 7.639 14.284 BLAminus DFGAsp-rot-in -121.18, 178.27 65.89, 75.15 190.5, -11.66 -84.6, 26.91 299.19, 79.94 -58.07, -32.45 in-in in 7.791 Saltbr-in 2.807 HRD-in -86.89, -55.74 82.47, 4.18 in-in-in SNCiii in-in ActLoopNT-in 2.839 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.8, 160.18 APE9-dihe-na 103.61, -173.61 APE8-dihe-in -78.9, 112.93 APE8-rot-in 304.74 APE67-dihe-in -56.6, -35.59 -54.54, -39.51 APE12-dist-in 13.701 APE11-dist-in 13.766 APE10-dist-in 7.989 APE9-dist-in 4.571 None None None XRAY 1.85 0.203 0.251 A 324 311 5 0 0 0 [[29, 315]] 1.0 8q1z Homo sapiens CK1_VRK2_HUMAN CK1 1.6e-103 351.6 1 261 261 185 186 187 189 191 61 73 77 163 165 164 166 232 220 215 214 213 212 211 210 209 122 Serine/threonine-protein kinase VRK2
CMGC MAPK14 MK14_HUMAN 9D6PA Q16539 5 353 360.0 A1IKD:60401 Type1 Inactive DFGin 4.165 14.29 None DFGAsp-rot-out -114.9917, 156.3089 64.0177, 34.1029 290.9979, -36.0041 -67.5205, 999.0 42.4914, 90.8481 -67.5205, 999.0 in-out in 9.994 Saltbr-out 3.889 HRD-in -73.2049, -53.4523 81.5844, -17.9664 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aannn APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none -69.781, -14.3674 999.0, 123.5057 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.13 0.213 0.244 A 346 335 11 0 0 11 [[24, 308]] 1.0 9d6p Homo sapiens CMGC_MAPK14_HUMAN CMGC 2.5e-79 272.7 1 301 301 167 168 169 173 175 53 71 75 147 149 148 150 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

Ligand: IKD

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name