Ligand: IJL

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ET1A
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ET1A P24941 1 298 298.0 IJL:60301,IJL:60302 Allosteric,Type1 Active DFGin 6.61 15.432 BLAminus -137.66, 172.68 58.27, 87.59 -100.93, 20.0 276.6, 76.94 -60.98, -28.65 in-in in 8.734 Saltbr-in 3.047 HRD-in -76.58, -65.76 87.89, 15.93 in-in-in SNCiii in-in ActLoopNT-in 3.205 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.13, 164.18 APE9-dihe-na 77.58, 126.34 APE8-dihe-in -49.84, 134.42 APE8-rot-in 305.88 APE67-dihe-in -58.89, -21.26 -48.0, -52.41 APE12-dist-in 13.1 APE11-dist-in 12.196 APE10-dist-in 7.293 APE9-dist-in 3.194 None TPO160 TPO160 XRAY 2.394 0.221 0.228 A 302 298 0 0 0 0 [[4, 286]] 1.0 9et1 CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET1C P24941 1 296 298.0 IJL:60301 Type1 Active DFGin 6.623 15.492 BLAminus -135.39, -177.33 51.33, 83.18 -94.5, 20.01 273.11, 76.66 -59.44, -32.33 in-in in 8.593 Saltbr-in 2.876 HRD-in -83.75, -57.91 76.36, 7.46 in-in-in SNCiii in-in ActLoopNT-in 2.987 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.5, 147.34 APE9-dihe-na 76.93, 124.91 APE8-dihe-in -54.11, 139.39 APE8-rot-in 309.88 APE67-dihe-in -59.67, -21.6 -42.38, -52.57 APE12-dist-in 12.846 APE11-dist-in 10.096 APE10-dist-in 7.185 APE9-dist-in 3.216 None TPO160 TPO160 XRAY 2.394 0.221 0.228 C 302 296 0 0 0 0 [[4, 286]] 1.0 9et1 CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: IJL

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ET1A
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ET1A P24941 1 298 298.0 IJL:60301,IJL:60302 Allosteric,Type1 Active DFGin 6.61 15.432 BLAminus -137.66, 172.68 58.27, 87.59 -100.93, 20.0 276.6, 76.94 -60.98, -28.65 in-in in 8.734 Saltbr-in 3.047 HRD-in -76.58, -65.76 87.89, 15.93 in-in-in SNCiii in-in ActLoopNT-in 3.205 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -69.13, 164.18 APE9-dihe-na 77.58, 126.34 APE8-dihe-in -49.84, 134.42 APE8-rot-in 305.88 APE67-dihe-in -58.89, -21.26 -48.0, -52.41 APE12-dist-in 13.1 APE11-dist-in 12.196 APE10-dist-in 7.293 APE9-dist-in 3.194 None TPO160 TPO160 XRAY 2.394 0.221 0.228 A 302 298 0 0 0 0 [[4, 286]] 1.0 9et1 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET1C P24941 1 296 298.0 IJL:60301 Type1 Active DFGin 6.623 15.492 BLAminus -135.39, -177.33 51.33, 83.18 -94.5, 20.01 273.11, 76.66 -59.44, -32.33 in-in in 8.593 Saltbr-in 2.876 HRD-in -83.75, -57.91 76.36, 7.46 in-in-in SNCiii in-in ActLoopNT-in 2.987 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.5, 147.34 APE9-dihe-na 76.93, 124.91 APE8-dihe-in -54.11, 139.39 APE8-rot-in 309.88 APE67-dihe-in -59.67, -21.6 -42.38, -52.57 APE12-dist-in 12.846 APE11-dist-in 10.096 APE10-dist-in 7.185 APE9-dist-in 3.216 None TPO160 TPO160 XRAY 2.394 0.221 0.228 C 302 296 0 0 0 0 [[4, 286]] 1.0 9et1 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: IJL

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name