| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | SRC | SRC_HUMAN | 6E6EA | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Inactive | DFGin | 6.9213 | 15.0759 | BLAminus | -130.82, -170.31 | 57.88, 75.94 | -103.97, 21.78 | 295.66, 100.83 | -66.87, -36.71 | in-in | in | 8.2611 | Saltbr-in | 2.5611 | HRD-in | -82.28, -51.16 | 77.92, -6.61 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9586 | ActLoopCT-out | TYR | APEdihe_ioiai | APEdist_aaai | APE10-dihe-in | -92.22, 124.09 | APE9-dihe-out | 23.0, 81.66 | APE8-dihe-in | -63.17, 123.3 | APE8-rot-na | 20.36 | APE67-dihe-in | -66.79, -22.96 | -56.43, -39.34 | APE12-dist-na | 999.0 | APE11-dist-na | 9.6364 | APE10-dist-na | 9.4981 | APE9-dist-in | 5.5134 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | A | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EC | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Active | DFGin | 6.5965 | 14.8515 | BLAminus | -129.99, -165.84 | 59.69, 74.53 | -102.54, 20.44 | 299.63, 111.42 | -67.27, -50.41 | in-in | in | 8.4796 | Saltbr-in | 2.7077 | HRD-in | -92.84, -50.69 | 79.53, -13.02 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8462 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -75.61, 141.29 | APE9-dihe-in | -138.47, 126.11 | APE8-dihe-in | -68.6, 128.58 | APE8-rot-na | 26.53 | APE67-dihe-in | -66.51, -21.53 | -63.92, -36.59 | APE12-dist-na | 999.0 | APE11-dist-na | 9.3236 | APE10-dist-na | 10.7423 | APE9-dist-in | 5.77 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | C | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6ED | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Active | DFGin | 6.8276 | 14.5752 | BLAminus | -125.31, -169.15 | 58.21, 80.68 | -107.69, 7.9 | 299.8, 110.32 | -69.05, -32.04 | in-in | in | 8.1719 | Saltbr-in | 2.5994 | HRD-in | -86.81, -48.25 | 78.28, -4.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.0204 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -166.59, 132.77 | APE9-dihe-in | -129.07, 145.85 | APE8-dihe-in | -84.48, 118.79 | APE8-rot-na | 22.08 | APE67-dihe-in | -72.37, -23.32 | -75.51, -8.7 | APE12-dist-na | 999.0 | APE11-dist-na | 8.3142 | APE10-dist-na | 10.1392 | APE9-dist-in | 5.9209 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | D | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EF | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Inactive | DFGin | 6.5143 | 14.3284 | BLAminus | -129.97, -166.54 | 57.74, 75.93 | -102.18, 13.17 | 308.17, 92.32 | -65.59, -36.48 | in-in | in | 8.5719 | Saltbr-in | 2.5758 | HRD-in | -82.73, -49.55 | 73.33, 1.4 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2062 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | 87.52, 115.28 | APE9-dihe-in | -143.23, 113.75 | APE8-dihe-in | -71.54, 127.01 | APE8-rot-na | 27.29 | APE67-dihe-in | -63.21, -30.95 | -76.64, -11.8 | APE12-dist-na | 999.0 | APE11-dist-na | 9.1679 | APE10-dist-na | 9.6847 | APE9-dist-in | 5.6264 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | F | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EH | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | None | DFGin | 7.029 | 15.2655 | BLAminus | -131.86, -170.63 | 59.19, 79.74 | -107.54, 18.21 | 299.51, 108.05 | -63.79, -34.15 | in-in | in | 8.5332 | Saltbr-in | 2.7293 | HRD-in | -94.19, -44.57 | 77.57, -18.69 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.3952 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -53.64 | APE8-dihe-in | -69.1, 125.41 | APE8-rot-na | 27.89 | APE67-dihe-in | -65.46, -25.99 | -62.37, -38.18 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 6.1115 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | H | 276.0 | 264.0 | 12 | 29 | 17 | 12 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EB | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1.5_Back | Inactive | DFGin | 6.9803 | 15.4272 | BLAminus | -127.66, -172.06 | 57.88, 77.04 | -103.69, 26.39 | 291.37, 98.21 | -68.61, -46.18 | in-in | in | 8.5199 | Saltbr-in | 2.3448 | HRD-in | -85.2, -49.94 | 77.68, -2.56 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1321 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -160.74, -64.33 | APE9-dihe-in | -165.05, 73.31 | APE8-dihe-in | -75.91, 109.47 | APE8-rot-na | 28.23 | APE67-dihe-in | -72.92, -22.9 | -69.73, -31.0 | APE12-dist-na | 999.0 | APE11-dist-na | 8.7239 | APE10-dist-na | 11.5039 | APE9-dist-in | 7.3128 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | B | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EE | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1.5_Back | Inactive | DFGin | 6.4689 | 14.2097 | BLAminus | -129.17, -172.64 | 60.07, 85.6 | -110.48, 23.37 | 306.63, 94.99 | -68.89, -45.48 | in-in | in | 8.596 | Saltbr-in | 2.5911 | HRD-in | -92.13, -45.09 | 72.91, 2.43 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1331 | ActLoopCT-out | TYR | APEdihe_ooiai | APEdist_aaai | APE10-dihe-out | -129.86, -69.27 | APE9-dihe-out | 66.26, 110.15 | APE8-dihe-in | -74.81, 133.32 | APE8-rot-na | 349.1 | APE67-dihe-in | -68.34, -22.87 | -70.07, -31.87 | APE12-dist-na | 999.0 | APE11-dist-na | 8.2817 | APE10-dist-na | 9.6304 | APE9-dist-in | 5.2603 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | E | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EG | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1.5_Back | Inactive | DFGin | 6.6917 | 14.3701 | BLAminus | -128.75, -172.38 | 59.68, 80.92 | -107.74, 14.89 | 305.82, 104.83 | -67.23, -35.47 | in-out | in | 8.2955 | Saltbr-out | 4.2093 | HRD-in | -84.15, -47.19 | 70.91, 8.62 | out-in-none | SNCoin | in-none | ActLoopNT-in | 2.9903 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -51.27 | APE8-dihe-in | -71.04, 100.53 | APE8-rot-na | 27.62 | APE67-dihe-in | -70.29, -23.48 | -70.07, -9.59 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 6.2681 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | G | 276.0 | 264.0 | 12 | 29 | 17 | 12 | [[270, 521]] | 1.0 | 6e6e | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | SRC | SRC_HUMAN | 6E6EA | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Inactive | DFGin | 6.9213 | 15.0759 | BLAminus | -130.82, -170.31 | 57.88, 75.94 | -103.97, 21.78 | 295.66, 100.83 | -66.87, -36.71 | in-in | in | 8.2611 | Saltbr-in | 2.5611 | HRD-in | -82.28, -51.16 | 77.92, -6.61 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.9586 | ActLoopCT-out | TYR | APEdihe_ioiai | APEdist_aaai | APE10-dihe-in | -92.22, 124.09 | APE9-dihe-out | 23.0, 81.66 | APE8-dihe-in | -63.17, 123.3 | APE8-rot-na | 20.36 | APE67-dihe-in | -66.79, -22.96 | -56.43, -39.34 | APE12-dist-na | 999.0 | APE11-dist-na | 9.6364 | APE10-dist-na | 9.4981 | APE9-dist-in | 5.5134 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | A | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EC | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Active | DFGin | 6.5965 | 14.8515 | BLAminus | -129.99, -165.84 | 59.69, 74.53 | -102.54, 20.44 | 299.63, 111.42 | -67.27, -50.41 | in-in | in | 8.4796 | Saltbr-in | 2.7077 | HRD-in | -92.84, -50.69 | 79.53, -13.02 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8462 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -75.61, 141.29 | APE9-dihe-in | -138.47, 126.11 | APE8-dihe-in | -68.6, 128.58 | APE8-rot-na | 26.53 | APE67-dihe-in | -66.51, -21.53 | -63.92, -36.59 | APE12-dist-na | 999.0 | APE11-dist-na | 9.3236 | APE10-dist-na | 10.7423 | APE9-dist-in | 5.77 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | C | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6ED | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Active | DFGin | 6.8276 | 14.5752 | BLAminus | -125.31, -169.15 | 58.21, 80.68 | -107.69, 7.9 | 299.8, 110.32 | -69.05, -32.04 | in-in | in | 8.1719 | Saltbr-in | 2.5994 | HRD-in | -86.81, -48.25 | 78.28, -4.24 | in-in-in | SNCiii | in-in | ActLoopNT-in | 3.0204 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -166.59, 132.77 | APE9-dihe-in | -129.07, 145.85 | APE8-dihe-in | -84.48, 118.79 | APE8-rot-na | 22.08 | APE67-dihe-in | -72.37, -23.32 | -75.51, -8.7 | APE12-dist-na | 999.0 | APE11-dist-na | 8.3142 | APE10-dist-na | 10.1392 | APE9-dist-in | 5.9209 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | D | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EF | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | Inactive | DFGin | 6.5143 | 14.3284 | BLAminus | -129.97, -166.54 | 57.74, 75.93 | -102.18, 13.17 | 308.17, 92.32 | -65.59, -36.48 | in-in | in | 8.5719 | Saltbr-in | 2.5758 | HRD-in | -82.73, -49.55 | 73.33, 1.4 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2062 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | 87.52, 115.28 | APE9-dihe-in | -143.23, 113.75 | APE8-dihe-in | -71.54, 127.01 | APE8-rot-na | 27.29 | APE67-dihe-in | -63.21, -30.95 | -76.64, -11.8 | APE12-dist-na | 999.0 | APE11-dist-na | 9.1679 | APE10-dist-na | 9.6847 | APE9-dist-in | 5.6264 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | F | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EH | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1 | None | DFGin | 7.029 | 15.2655 | BLAminus | -131.86, -170.63 | 59.19, 79.74 | -107.54, 18.21 | 299.51, 108.05 | -63.79, -34.15 | in-in | in | 8.5332 | Saltbr-in | 2.7293 | HRD-in | -94.19, -44.57 | 77.57, -18.69 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.3952 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -53.64 | APE8-dihe-in | -69.1, 125.41 | APE8-rot-na | 27.89 | APE67-dihe-in | -65.46, -25.99 | -62.37, -38.18 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 6.1115 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | H | 276.0 | 264.0 | 12 | 29 | 17 | 12 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EB | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1.5_Back | Inactive | DFGin | 6.9803 | 15.4272 | BLAminus | -127.66, -172.06 | 57.88, 77.04 | -103.69, 26.39 | 291.37, 98.21 | -68.61, -46.18 | in-in | in | 8.5199 | Saltbr-in | 2.3448 | HRD-in | -85.2, -49.94 | 77.68, -2.56 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1321 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -160.74, -64.33 | APE9-dihe-in | -165.05, 73.31 | APE8-dihe-in | -75.91, 109.47 | APE8-rot-na | 28.23 | APE67-dihe-in | -72.92, -22.9 | -69.73, -31.0 | APE12-dist-na | 999.0 | APE11-dist-na | 8.7239 | APE10-dist-na | 11.5039 | APE9-dist-in | 7.3128 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | B | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EE | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1.5_Back | Inactive | DFGin | 6.4689 | 14.2097 | BLAminus | -129.17, -172.64 | 60.07, 85.6 | -110.48, 23.37 | 306.63, 94.99 | -68.89, -45.48 | in-in | in | 8.596 | Saltbr-in | 2.5911 | HRD-in | -92.13, -45.09 | 72.91, 2.43 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.1331 | ActLoopCT-out | TYR | APEdihe_ooiai | APEdist_aaai | APE10-dihe-out | -129.86, -69.27 | APE9-dihe-out | 66.26, 110.15 | APE8-dihe-in | -74.81, 133.32 | APE8-rot-na | 349.1 | APE67-dihe-in | -68.34, -22.87 | -70.07, -31.87 | APE12-dist-na | 999.0 | APE11-dist-na | 8.2817 | APE10-dist-na | 9.6304 | APE9-dist-in | 5.2603 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | E | 276.0 | 266.0 | 10 | 29 | 19 | 10 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| TYR | SRC | SRC_HUMAN | 6E6EG | P12931 | 261 | 536 | 536.0 | HVY:601 | Type1.5_Back | Inactive | DFGin | 6.6917 | 14.3701 | BLAminus | -128.75, -172.38 | 59.68, 80.92 | -107.74, 14.89 | 305.82, 104.83 | -67.23, -35.47 | in-out | in | 8.2955 | Saltbr-out | 4.2093 | HRD-in | -84.15, -47.19 | 70.91, 8.62 | out-in-none | SNCoin | in-none | ActLoopNT-in | 2.9903 | ActLoopCT-none | TYR | APEdihe_nniai | APEdist_aaai | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, -51.27 | APE8-dihe-in | -71.04, 100.53 | APE8-rot-na | 27.62 | APE67-dihe-in | -70.29, -23.48 | -70.07, -9.59 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-in | 6.2681 | None | None | None | XRAY | 2.15 | 0.252 | 0.285 | G | 276.0 | 264.0 | 12 | 29 | 17 | 12 | [[270, 521]] | 1.0 | 6e6e | Homo sapiens | TYR_SRC_HUMAN | TYR | 1.4e-94 | 322.2 | 1.0 | 260.0 | 260.0 | 406 | 407 | 408 | 410 | 412 | 298 | 313 | 317 | 386 | 388 | 387 | 389.0 | 447 | 435 | 430 | 429 | 428 | 427 | 426 | 425 | 424 | 342 | Proto-oncogene tyrosine-protein kinase Src |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|