Ligand: HHN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9ET0A
None None 1 33.3% 6Q4BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ET0A P24941 1 298 298.0 HHN:60301 Type1 Active DFGin 6.6376 15.2414 BLAminus -134.9, 175.1 57.37, 82.81 -94.18, 18.73 280.11, 75.28 -62.18, -27.41 in-in in 8.7164 Saltbr-in 3.021 HRD-in -79.22, -60.59 80.44, 14.72 in-in-in SNCiii in-in ActLoopNT-in 2.9857 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -60.34, 170.44 APE9-dihe-na 75.62, 129.42 APE8-dihe-in -52.98, 137.89 APE8-rot-in 301.96 APE67-dihe-in -61.35, -20.22 -51.89, -49.35 APE12-dist-in 13.1122 APE11-dist-in 11.9978 APE10-dist-in 7.1189 APE9-dist-in 3.2426 None TPO160 TPO160 XRAY 2.239 0.235 0.239 A 302.0 298.0 0 28 28 0 [[4, 286]] 1.0 9et0 CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET0C P24941 1 296 298.0 HHN:60301 Type1 Active DFGin 6.733 15.6379 BLAminus -141.22, -178.98 56.42, 68.49 -82.49, 27.84 282.91, 72.01 -73.64, -20.97 in-in in 8.6224 Saltbr-in 2.7471 HRD-in -80.75, -59.23 74.38, 11.19 in-in-in SNCiii in-in ActLoopNT-in 2.8956 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.37, 152.48 APE9-dihe-na 75.08, 131.84 APE8-dihe-in -56.51, 137.62 APE8-rot-in 304.65 APE67-dihe-in -57.06, -22.75 -41.43, -52.94 APE12-dist-in 12.8383 APE11-dist-in 10.4348 APE10-dist-in 6.8381 APE9-dist-in 3.1716 None TPO160 TPO160 XRAY 2.239 0.235 0.239 C 302.0 296.0 0 28 28 0 [[4, 286]] 1.0 9et0 CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6Q4BA P24941 1 298 298.0 HHN:301 Type1 Inactive None 11.2868 18.4067 None -101.91, 152.75 72.94, 19.11 -57.76, 142.71 248.24, 88.8 81.19, -13.46 out-out out 15.3141 Saltbr-out 15.9838 HRD-in -89.83, -61.58 81.31, -13.01 out-out-out SNCooo out-out ActLoopNT-out 5.6648 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -77.3, 127.49 APE9-dihe-na -72.88, 129.85 APE8-dihe-in -66.95, 144.25 APE8-rot-out 190.39 APE67-dihe-in -63.63, -25.03 -98.0, -6.38 APE12-dist-out 21.1533 APE11-dist-out 18.2408 APE10-dist-out 19.458 APE9-dist-out 10.7292 None None None XRAY 1.12 0.174 0.203 A 306.0 291.0 7 28 28 0 [[4, 286]] 1.0 6q4b CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: HHN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9ET0A
None None 1 33.3% 6Q4BA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ET0A P24941 1 298 298.0 HHN:60301 Type1 Active DFGin 6.6376 15.2414 BLAminus -134.9, 175.1 57.37, 82.81 -94.18, 18.73 280.11, 75.28 -62.18, -27.41 in-in in 8.7164 Saltbr-in 3.021 HRD-in -79.22, -60.59 80.44, 14.72 in-in-in SNCiii in-in ActLoopNT-in 2.9857 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -60.34, 170.44 APE9-dihe-na 75.62, 129.42 APE8-dihe-in -52.98, 137.89 APE8-rot-in 301.96 APE67-dihe-in -61.35, -20.22 -51.89, -49.35 APE12-dist-in 13.1122 APE11-dist-in 11.9978 APE10-dist-in 7.1189 APE9-dist-in 3.2426 None TPO160 TPO160 XRAY 2.239 0.235 0.239 A 302.0 298.0 0 28 28 0 [[4, 286]] 1.0 9et0 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ET0C P24941 1 296 298.0 HHN:60301 Type1 Active DFGin 6.733 15.6379 BLAminus -141.22, -178.98 56.42, 68.49 -82.49, 27.84 282.91, 72.01 -73.64, -20.97 in-in in 8.6224 Saltbr-in 2.7471 HRD-in -80.75, -59.23 74.38, 11.19 in-in-in SNCiii in-in ActLoopNT-in 2.8956 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.37, 152.48 APE9-dihe-na 75.08, 131.84 APE8-dihe-in -56.51, 137.62 APE8-rot-in 304.65 APE67-dihe-in -57.06, -22.75 -41.43, -52.94 APE12-dist-in 12.8383 APE11-dist-in 10.4348 APE10-dist-in 6.8381 APE9-dist-in 3.1716 None TPO160 TPO160 XRAY 2.239 0.235 0.239 C 302.0 296.0 0 28 28 0 [[4, 286]] 1.0 9et0 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6Q4BA P24941 1 298 298.0 HHN:301 Type1 Inactive None 11.2868 18.4067 None -101.91, 152.75 72.94, 19.11 -57.76, 142.71 248.24, 88.8 81.19, -13.46 out-out out 15.3141 Saltbr-out 15.9838 HRD-in -89.83, -61.58 81.31, -13.01 out-out-out SNCooo out-out ActLoopNT-out 5.6648 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -77.3, 127.49 APE9-dihe-na -72.88, 129.85 APE8-dihe-in -66.95, 144.25 APE8-rot-out 190.39 APE67-dihe-in -63.63, -25.03 -98.0, -6.38 APE12-dist-out 21.1533 APE11-dist-out 18.2408 APE10-dist-out 19.458 APE9-dist-out 10.7292 None None None XRAY 1.12 0.174 0.203 A 306.0 291.0 7 28 28 0 [[4, 286]] 1.0 6q4b Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: HHN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name