Ligand: HGW

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9ESZA
None None 1 33.3% 6Q4AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESZA P24941 1 292 298.0 HGW:60601 Type1 Active DFGin 6.5776 15.3324 BLAminus -132.04, 171.04 63.6, 85.87 -98.66, 25.0 277.0, 76.47 -70.53, -27.06 in-in in 8.6416 Saltbr-in 3.0007 HRD-in -80.25, -60.98 81.99, 14.7 in-in-in SNCiii in-in ActLoopNT-in 2.9882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -71.52, 168.74 APE9-dihe-na 75.8, 128.24 APE8-dihe-in -49.62, 139.46 APE8-rot-in 302.85 APE67-dihe-in -59.69, -19.57 -54.76, -48.33 APE12-dist-in 13.123 APE11-dist-in 12.0773 APE10-dist-in 7.0857 APE9-dist-in 3.2484 None TPO160 TPO160 XRAY 2.42 0.212 0.213 A 302.0 292.0 0 28 28 0 [[4, 286]] 1.0 9esz CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESZC P24941 1 296 298.0 HGW:60501 Type1 Active DFGin 6.6994 15.3762 BLAminus -138.8, -176.72 49.7, 80.72 -92.52, 24.31 277.61, 74.75 -64.18, -24.0 in-in in 8.4557 Saltbr-in 2.9658 HRD-in -81.04, -55.78 70.54, 14.46 in-in-in SNCiii in-in ActLoopNT-in 2.8466 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.11, 146.25 APE9-dihe-na 77.04, 123.95 APE8-dihe-in -50.26, 136.24 APE8-rot-in 297.63 APE67-dihe-in -54.0, -25.83 -45.3, -55.89 APE12-dist-in 13.0314 APE11-dist-in 10.4577 APE10-dist-in 7.148 APE9-dist-in 3.2502 None TPO160 TPO160 XRAY 2.42 0.212 0.213 C 302.0 296.0 0 28 28 0 [[4, 286]] 1.0 9esz CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6Q4AA P24941 1 298 298.0 HGW:301 Type1 Inactive None 11.3058 18.4844 None -99.64, 151.34 71.13, 19.02 -56.46, 143.53 245.43, 97.69 75.11, -5.52 out-out out 15.3944 Saltbr-out 16.3628 HRD-in -87.49, -64.78 82.76, -10.85 out-out-out SNCooo out-out ActLoopNT-out 5.8722 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -54.84, 127.77 APE9-dihe-na -73.06, 129.93 APE8-dihe-in -62.58, 141.11 APE8-rot-out 189.02 APE67-dihe-in -63.75, -25.74 -99.36, -2.17 APE12-dist-out 21.026 APE11-dist-out 17.7543 APE10-dist-out 19.3636 APE9-dist-out 10.597 None None None XRAY 1.13 0.184 0.22 A 306.0 292.0 6 28 28 0 [[4, 286]] 1.0 6q4a CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: HGW

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 9ESZA
None None 1 33.3% 6Q4AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ESZA P24941 1 292 298.0 HGW:60601 Type1 Active DFGin 6.5776 15.3324 BLAminus -132.04, 171.04 63.6, 85.87 -98.66, 25.0 277.0, 76.47 -70.53, -27.06 in-in in 8.6416 Saltbr-in 3.0007 HRD-in -80.25, -60.98 81.99, 14.7 in-in-in SNCiii in-in ActLoopNT-in 2.9882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -71.52, 168.74 APE9-dihe-na 75.8, 128.24 APE8-dihe-in -49.62, 139.46 APE8-rot-in 302.85 APE67-dihe-in -59.69, -19.57 -54.76, -48.33 APE12-dist-in 13.123 APE11-dist-in 12.0773 APE10-dist-in 7.0857 APE9-dist-in 3.2484 None TPO160 TPO160 XRAY 2.42 0.212 0.213 A 302.0 292.0 0 28 28 0 [[4, 286]] 1.0 9esz Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ESZC P24941 1 296 298.0 HGW:60501 Type1 Active DFGin 6.6994 15.3762 BLAminus -138.8, -176.72 49.7, 80.72 -92.52, 24.31 277.61, 74.75 -64.18, -24.0 in-in in 8.4557 Saltbr-in 2.9658 HRD-in -81.04, -55.78 70.54, 14.46 in-in-in SNCiii in-in ActLoopNT-in 2.8466 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.11, 146.25 APE9-dihe-na 77.04, 123.95 APE8-dihe-in -50.26, 136.24 APE8-rot-in 297.63 APE67-dihe-in -54.0, -25.83 -45.3, -55.89 APE12-dist-in 13.0314 APE11-dist-in 10.4577 APE10-dist-in 7.148 APE9-dist-in 3.2502 None TPO160 TPO160 XRAY 2.42 0.212 0.213 C 302.0 296.0 0 28 28 0 [[4, 286]] 1.0 9esz Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 6Q4AA P24941 1 298 298.0 HGW:301 Type1 Inactive None 11.3058 18.4844 None -99.64, 151.34 71.13, 19.02 -56.46, 143.53 245.43, 97.69 75.11, -5.52 out-out out 15.3944 Saltbr-out 16.3628 HRD-in -87.49, -64.78 82.76, -10.85 out-out-out SNCooo out-out ActLoopNT-out 5.8722 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -54.84, 127.77 APE9-dihe-na -73.06, 129.93 APE8-dihe-in -62.58, 141.11 APE8-rot-out 189.02 APE67-dihe-in -63.75, -25.74 -99.36, -2.17 APE12-dist-out 21.026 APE11-dist-out 17.7543 APE10-dist-out 19.3636 APE9-dist-out 10.597 None None None XRAY 1.13 0.184 0.22 A 306.0 292.0 6 28 28 0 [[4, 286]] 1.0 6q4a Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: HGW

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name