Ligand: H3H

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6I5KA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6I5KA P49759 148 482 484.0 H3H:60503 Type1 Inactive DFGin 7.0191 14.2807 BLAminus -127.95, 177.21 67.34, 85.43 -106.5, 25.82 299.72, 92.63 -80.22, -14.39 in-in in 8.8988 Saltbr-in 2.6726 HRD-in -72.89, -48.86 76.37, -11.75 in-in-out SNCiio in-out ActLoopNT-in 3.0079 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -139.66, 157.93 APE9-dihe-na -83.57, -145.55 APE8-dihe-in -77.05, 120.2 APE8-rot-in 311.82 APE67-dihe-out -112.74, 31.9 -178.22, 144.22 APE12-dist-out 14.3954 APE11-dist-in 12.6175 APE10-dist-out 8.7668 APE9-dist-out 8.7264 None None None XRAY 2.3 0.197 0.224 A 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6i5k CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6I5KB P49759 148 481 484.0 H3H:60504 Type1 Active DFGin 7.006 14.3591 BLAminus -126.82, 178.06 66.53, 84.63 -104.0, 26.37 299.27, 91.89 -80.46, -16.31 in-in in 9.0291 Saltbr-in 2.6927 HRD-in -71.59, -48.77 75.18, -11.75 in-in-in SNCiii in-in ActLoopNT-in 2.9844 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.96, 164.13 APE9-dihe-na 74.43, 150.15 APE8-dihe-in -66.68, 137.66 APE8-rot-in 303.78 APE67-dihe-in -77.74, -18.3 -54.0, -31.51 APE12-dist-in 13.8442 APE11-dist-in 11.2244 APE10-dist-in 7.3953 APE9-dist-in 3.093 None None None XRAY 2.3 0.197 0.224 B 339.0 334.0 0 25 25 0 [[161, 477]] 1.0 6i5k CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6I5KC P49759 148 483 484.0 H3H:60504 Type1 Active DFGin 6.9865 14.3514 BLAminus -125.41, 178.1 66.91, 85.45 -105.62, 25.72 298.18, 84.65 -79.89, -19.48 in-in in 8.919 Saltbr-in 2.6659 HRD-in -72.35, -49.89 76.53, -11.56 in-in-in SNCiii in-in ActLoopNT-in 3.0005 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.9, 163.92 APE9-dihe-na 72.8, 149.97 APE8-dihe-in -66.75, 139.4 APE8-rot-in 303.5 APE67-dihe-in -77.85, -17.5 -52.64, -34.11 APE12-dist-in 13.6161 APE11-dist-in 11.124 APE10-dist-in 7.3407 APE9-dist-in 3.1121 None None None XRAY 2.3 0.197 0.224 C 339.0 336.0 0 25 25 0 [[161, 477]] 1.0 6i5k CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: H3H

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6I5KA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6I5KA P49759 148 482 484.0 H3H:60503 Type1 Inactive DFGin 7.0191 14.2807 BLAminus -127.95, 177.21 67.34, 85.43 -106.5, 25.82 299.72, 92.63 -80.22, -14.39 in-in in 8.8988 Saltbr-in 2.6726 HRD-in -72.89, -48.86 76.37, -11.75 in-in-out SNCiio in-out ActLoopNT-in 3.0079 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -139.66, 157.93 APE9-dihe-na -83.57, -145.55 APE8-dihe-in -77.05, 120.2 APE8-rot-in 311.82 APE67-dihe-out -112.74, 31.9 -178.22, 144.22 APE12-dist-out 14.3954 APE11-dist-in 12.6175 APE10-dist-out 8.7668 APE9-dist-out 8.7264 None None None XRAY 2.3 0.197 0.224 A 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6i5k Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6I5KB P49759 148 481 484.0 H3H:60504 Type1 Active DFGin 7.006 14.3591 BLAminus -126.82, 178.06 66.53, 84.63 -104.0, 26.37 299.27, 91.89 -80.46, -16.31 in-in in 9.0291 Saltbr-in 2.6927 HRD-in -71.59, -48.77 75.18, -11.75 in-in-in SNCiii in-in ActLoopNT-in 2.9844 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.96, 164.13 APE9-dihe-na 74.43, 150.15 APE8-dihe-in -66.68, 137.66 APE8-rot-in 303.78 APE67-dihe-in -77.74, -18.3 -54.0, -31.51 APE12-dist-in 13.8442 APE11-dist-in 11.2244 APE10-dist-in 7.3953 APE9-dist-in 3.093 None None None XRAY 2.3 0.197 0.224 B 339.0 334.0 0 25 25 0 [[161, 477]] 1.0 6i5k Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6I5KC P49759 148 483 484.0 H3H:60504 Type1 Active DFGin 6.9865 14.3514 BLAminus -125.41, 178.1 66.91, 85.45 -105.62, 25.72 298.18, 84.65 -79.89, -19.48 in-in in 8.919 Saltbr-in 2.6659 HRD-in -72.35, -49.89 76.53, -11.56 in-in-in SNCiii in-in ActLoopNT-in 3.0005 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -142.9, 163.92 APE9-dihe-na 72.8, 149.97 APE8-dihe-in -66.75, 139.4 APE8-rot-in 303.5 APE67-dihe-in -77.85, -17.5 -52.64, -34.11 APE12-dist-in 13.6161 APE11-dist-in 11.124 APE10-dist-in 7.3407 APE9-dist-in 3.1121 None None None XRAY 2.3 0.197 0.224 C 339.0 336.0 0 25 25 0 [[161, 477]] 1.0 6i5k Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: H3H

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name