Ligand: G6T

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4CFXA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4CFXA P24941 1 298 298.0 G6T:61299 Type1 Active DFGin 6.601 15.153 BLAminus -137.97, 169.05 56.34, 77.85 -94.42, 27.07 283.56, 72.41 -55.94, -34.34 in-in in 8.739 Saltbr-in 3.413 HRD-in -80.0, -48.77 67.93, 12.9 in-in-in SNCiii in-in ActLoopNT-in 2.865 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.93, 133.26 APE9-dihe-na -134.31, -168.88 APE8-dihe-in -52.68, 136.23 APE8-rot-in 289.49 APE67-dihe-in -51.99, -24.9 -51.69, -52.0 APE12-dist-in 13.144 APE11-dist-in 10.601 APE10-dist-in 7.605 APE9-dist-in 3.485 None TPO160 TPO160 XRAY 3.5 0.207 0.269 A 303 298 0 0 0 0 [[4, 286]] 1.0 4cfx CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4CFXC P24941 1 298 298.0 G6T:61299 Type1 Active DFGin 6.754 15.157 BLAminus -142.34, 170.11 55.48, 71.6 -85.7, 23.38 285.39, 68.53 -51.58, -29.63 in-in in 8.846 Saltbr-in 2.538 HRD-in -79.55, -56.78 72.59, 13.73 in-in-in SNCiii in-in ActLoopNT-in 2.935 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.79, 170.79 APE9-dihe-na 64.39, -170.45 APE8-dihe-in -117.6, 151.27 APE8-rot-in 271.11 APE67-dihe-in -61.81, -23.06 -60.79, -44.0 APE12-dist-in 12.996 APE11-dist-in 10.555 APE10-dist-in 7.357 APE9-dist-in 3.111 None TPO160 TPO160 XRAY 3.5 0.207 0.269 C 303 298 0 0 0 0 [[4, 286]] 1.0 4cfx CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: G6T

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4CFXA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4CFXA P24941 1 298 298.0 G6T:61299 Type1 Active DFGin 6.601 15.153 BLAminus -137.97, 169.05 56.34, 77.85 -94.42, 27.07 283.56, 72.41 -55.94, -34.34 in-in in 8.739 Saltbr-in 3.413 HRD-in -80.0, -48.77 67.93, 12.9 in-in-in SNCiii in-in ActLoopNT-in 2.865 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -164.93, 133.26 APE9-dihe-na -134.31, -168.88 APE8-dihe-in -52.68, 136.23 APE8-rot-in 289.49 APE67-dihe-in -51.99, -24.9 -51.69, -52.0 APE12-dist-in 13.144 APE11-dist-in 10.601 APE10-dist-in 7.605 APE9-dist-in 3.485 None TPO160 TPO160 XRAY 3.5 0.207 0.269 A 303 298 0 0 0 0 [[4, 286]] 1.0 4cfx Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4CFXC P24941 1 298 298.0 G6T:61299 Type1 Active DFGin 6.754 15.157 BLAminus -142.34, 170.11 55.48, 71.6 -85.7, 23.38 285.39, 68.53 -51.58, -29.63 in-in in 8.846 Saltbr-in 2.538 HRD-in -79.55, -56.78 72.59, 13.73 in-in-in SNCiii in-in ActLoopNT-in 2.935 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.79, 170.79 APE9-dihe-na 64.39, -170.45 APE8-dihe-in -117.6, 151.27 APE8-rot-in 271.11 APE67-dihe-in -61.81, -23.06 -60.79, -44.0 APE12-dist-in 12.996 APE11-dist-in 10.555 APE10-dist-in 7.357 APE9-dist-in 3.111 None TPO160 TPO160 XRAY 3.5 0.207 0.269 C 303 298 0 0 0 0 [[4, 286]] 1.0 4cfx Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: G6T

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name