Ligand: G6J

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6DD4D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6DD4B Q99986 23 341 396.0 G6J:401 Type1 Inactive DFGin 8.4934 14.5728 BLAminus -116.27, 174.1 65.5, 83.71 -97.19, 25.82 292.92, 76.04 -69.31, -16.08 in-in in 7.4479 Saltbr-in 2.7507 HRD-in -89.8, -46.83 77.94, -2.82 in-in-out SNCiio in-out ActLoopNT-in 2.9315 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -56.91, 145.7 APE9-dihe-na 104.42, -168.67 APE8-dihe-in -90.31, 119.08 APE8-rot-in 302.84 APE67-dihe-in -69.05, -22.86 -50.85, -45.39 APE12-dist-out 14.9402 APE11-dist-in 13.112 APE10-dist-in 7.4454 APE9-dist-in 4.1503 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.196 0.226 B 364.0 309.0 10 35 35 0 [[37, 326]] 1.0 6dd4 CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6DD4D Q99986 22 341 396.0 G6J:401 Type1 Inactive DFGin 8.3185 14.452 BLAminus -110.97, 176.15 62.45, 87.29 -93.85, 25.94 291.26, 76.36 -66.64, -23.33 in-in in 7.6445 Saltbr-in 2.978 HRD-in -93.42, -46.94 76.68, -1.24 in-in-out SNCiio in-out ActLoopNT-in 2.8982 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -53.05, 149.42 APE9-dihe-na 99.37, -171.31 APE8-dihe-in -92.36, 120.15 APE8-rot-in 301.82 APE67-dihe-in -63.05, -32.03 -54.27, -42.37 APE12-dist-out 14.7753 APE11-dist-in 13.1152 APE10-dist-in 7.3506 APE9-dist-in 4.0495 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.196 0.226 D 364.0 311.0 9 35 35 0 [[37, 326]] 1.0 6dd4 CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

Ligand: G6J

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6DD4D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6DD4B Q99986 23 341 396.0 G6J:401 Type1 Inactive DFGin 8.4934 14.5728 BLAminus -116.27, 174.1 65.5, 83.71 -97.19, 25.82 292.92, 76.04 -69.31, -16.08 in-in in 7.4479 Saltbr-in 2.7507 HRD-in -89.8, -46.83 77.94, -2.82 in-in-out SNCiio in-out ActLoopNT-in 2.9315 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -56.91, 145.7 APE9-dihe-na 104.42, -168.67 APE8-dihe-in -90.31, 119.08 APE8-rot-in 302.84 APE67-dihe-in -69.05, -22.86 -50.85, -45.39 APE12-dist-out 14.9402 APE11-dist-in 13.112 APE10-dist-in 7.4454 APE9-dist-in 4.1503 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.196 0.226 B 364.0 309.0 10 35 35 0 [[37, 326]] 1.0 6dd4 Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6DD4D Q99986 22 341 396.0 G6J:401 Type1 Inactive DFGin 8.3185 14.452 BLAminus -110.97, 176.15 62.45, 87.29 -93.85, 25.94 291.26, 76.36 -66.64, -23.33 in-in in 7.6445 Saltbr-in 2.978 HRD-in -93.42, -46.94 76.68, -1.24 in-in-out SNCiio in-out ActLoopNT-in 2.8982 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -53.05, 149.42 APE9-dihe-na 99.37, -171.31 APE8-dihe-in -92.36, 120.15 APE8-rot-in 301.82 APE67-dihe-in -63.05, -32.03 -54.27, -42.37 APE12-dist-out 14.7753 APE11-dist-in 13.1152 APE10-dist-in 7.3506 APE9-dist-in 4.0495 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 2.1 0.196 0.226 D 364.0 311.0 9 35 35 0 [[37, 326]] 1.0 6dd4 Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

Ligand: G6J

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name