Ligand: F6J

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6CMJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK CAMKK2 KKCC2_HUMAN 6CMJA Q96RR4 161 463 588.0 F6J:60501 Type1 Active DFGin 6.7009 14.0205 BLAminus -128.16, 173.53 66.84, 86.55 -100.45, 21.53 286.63, 76.45 -58.11, -34.47 in-in in 9.5163 Saltbr-in 2.7082 HRD-in -70.27, -50.6 73.87, 2.96 in-in-in SNCiii in-in ActLoopNT-in 2.9477 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.24, 163.41 APE9-dihe-na 103.64, -157.45 APE8-dihe-in -90.88, 126.33 APE8-rot-in 303.07 APE67-dihe-in -67.03, -16.03 -51.77, -42.09 APE12-dist-in 9.9798 APE11-dist-in 11.1344 APE10-dist-in 5.2592 APE9-dist-in 3.8169 None SEP345,SEP400,TPO462 SEP345,SEP400,TPO462 XRAY 2.4 0.184 0.219 A 321.0 288.0 0 28 28 0 [[165, 446]] 1.0 6cmj CAMK_CAMKK2_HUMAN CAMK 2.4e-75 259.1 1.0 256.0 256.0 329 330 331 333 335 194 236 240 309 311 310 312.0 372 357 352 351 350 349 348 347 346 268 Calcium/calmodulin-dependent protein kinase kinase 2
CAMK CAMKK2 KKCC2_HUMAN 6CMJB Q96RR4 161 462 588.0 F6J:60501 Type1 Active DFGin 6.5539 14.022 BLAminus -126.23, 173.65 67.8, 86.78 -100.71, 20.95 284.77, 76.92 -57.77, -33.94 in-in in 9.4714 Saltbr-in 2.7026 HRD-in -69.56, -50.79 72.39, 3.04 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.14, 163.72 APE9-dihe-na 103.15, -157.71 APE8-dihe-in -91.26, 126.78 APE8-rot-in 302.39 APE67-dihe-in -66.21, -16.47 -51.31, -43.01 APE12-dist-in 9.8488 APE11-dist-in 11.0819 APE10-dist-in 5.2245 APE9-dist-in 3.8201 None SEP345,SEP400,TPO462 SEP345,SEP400,TPO462 XRAY 2.4 0.184 0.219 B 321.0 287.0 0 28 28 0 [[165, 446]] 1.0 6cmj CAMK_CAMKK2_HUMAN CAMK 2.4e-75 259.1 1.0 256.0 256.0 329 330 331 333 335 194 236 240 309 311 310 312.0 372 357 352 351 350 349 348 347 346 268 Calcium/calmodulin-dependent protein kinase kinase 2

Ligand: F6J

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6CMJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK CAMKK2 KKCC2_HUMAN 6CMJA Q96RR4 161 463 588.0 F6J:60501 Type1 Active DFGin 6.7009 14.0205 BLAminus -128.16, 173.53 66.84, 86.55 -100.45, 21.53 286.63, 76.45 -58.11, -34.47 in-in in 9.5163 Saltbr-in 2.7082 HRD-in -70.27, -50.6 73.87, 2.96 in-in-in SNCiii in-in ActLoopNT-in 2.9477 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.24, 163.41 APE9-dihe-na 103.64, -157.45 APE8-dihe-in -90.88, 126.33 APE8-rot-in 303.07 APE67-dihe-in -67.03, -16.03 -51.77, -42.09 APE12-dist-in 9.9798 APE11-dist-in 11.1344 APE10-dist-in 5.2592 APE9-dist-in 3.8169 None SEP345,SEP400,TPO462 SEP345,SEP400,TPO462 XRAY 2.4 0.184 0.219 A 321.0 288.0 0 28 28 0 [[165, 446]] 1.0 6cmj Homo sapiens CAMK_CAMKK2_HUMAN CAMK 2.4e-75 259.1 1.0 256.0 256.0 329 330 331 333 335 194 236 240 309 311 310 312.0 372 357 352 351 350 349 348 347 346 268 Calcium/calmodulin-dependent protein kinase kinase 2
CAMK CAMKK2 KKCC2_HUMAN 6CMJB Q96RR4 161 462 588.0 F6J:60501 Type1 Active DFGin 6.5539 14.022 BLAminus -126.23, 173.65 67.8, 86.78 -100.71, 20.95 284.77, 76.92 -57.77, -33.94 in-in in 9.4714 Saltbr-in 2.7026 HRD-in -69.56, -50.79 72.39, 3.04 in-in-in SNCiii in-in ActLoopNT-in 2.937 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.14, 163.72 APE9-dihe-na 103.15, -157.71 APE8-dihe-in -91.26, 126.78 APE8-rot-in 302.39 APE67-dihe-in -66.21, -16.47 -51.31, -43.01 APE12-dist-in 9.8488 APE11-dist-in 11.0819 APE10-dist-in 5.2245 APE9-dist-in 3.8201 None SEP345,SEP400,TPO462 SEP345,SEP400,TPO462 XRAY 2.4 0.184 0.219 B 321.0 287.0 0 28 28 0 [[165, 446]] 1.0 6cmj Homo sapiens CAMK_CAMKK2_HUMAN CAMK 2.4e-75 259.1 1.0 256.0 256.0 329 330 331 333 335 194 236 240 309 311 310 312.0 372 357 352 351 350 349 348 347 346 268 Calcium/calmodulin-dependent protein kinase kinase 2

Ligand: F6J

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name