Ligand: F48

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6GLBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 6GLBA P52333 813 1103 1124.0 F48:1201 Type1 None DFGin 6.0868 14.0047 BLAminus -127.29, -165.11 42.2, 80.94 -98.99, 18.18 281.6, 72.22 -46.91, -40.63 in-in in 7.5761 Saltbr-in 2.7125 HRD-in -78.7, -52.76 77.75, 9.6 in-in-none SNCiin in-none ActLoopNT-in 2.7344 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 129.22 APE9-dihe-in -106.96, 151.72 APE8-dihe-in -79.63, 91.52 APE8-rot-na 32.17 APE67-dihe-in -74.91, -5.23 -62.01, -34.09 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.734 APE9-dist-in 6.7274 None None None XRAY 2.0 0.236 0.29 A 294.0 288.0 3 31 28 3 [[521, 779], [822, 1097]] 2.0 6glb TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLBB P52333 813 1103 1124.0 F48:1201 Type1 None DFGin 6.117 14.0249 BLAminus -125.81, -165.95 42.86, 80.87 -97.87, 18.6 282.22, 74.99 -51.1, -37.8 in-in in 7.5451 Saltbr-in 2.7085 HRD-in -76.97, -51.62 77.21, 8.56 in-in-none SNCiin in-none ActLoopNT-in 2.7568 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 130.97 APE9-dihe-in -105.16, 150.45 APE8-dihe-in -79.13, 89.35 APE8-rot-na 33.14 APE67-dihe-in -76.14, -3.82 -57.76, -35.85 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.6293 APE9-dist-in 6.7039 None None None XRAY 2.0 0.236 0.29 B 294.0 288.0 3 31 28 3 [[521, 779], [822, 1097]] 2.0 6glb TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

Ligand: F48

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6GLBA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 6GLBA P52333 813 1103 1124.0 F48:1201 Type1 None DFGin 6.0868 14.0047 BLAminus -127.29, -165.11 42.2, 80.94 -98.99, 18.18 281.6, 72.22 -46.91, -40.63 in-in in 7.5761 Saltbr-in 2.7125 HRD-in -78.7, -52.76 77.75, 9.6 in-in-none SNCiin in-none ActLoopNT-in 2.7344 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 129.22 APE9-dihe-in -106.96, 151.72 APE8-dihe-in -79.63, 91.52 APE8-rot-na 32.17 APE67-dihe-in -74.91, -5.23 -62.01, -34.09 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.734 APE9-dist-in 6.7274 None None None XRAY 2.0 0.236 0.29 A 294.0 288.0 3 31 28 3 [[521, 779], [822, 1097]] 2.0 6glb Homo sapiens TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 6GLBB P52333 813 1103 1124.0 F48:1201 Type1 None DFGin 6.117 14.0249 BLAminus -125.81, -165.95 42.86, 80.87 -97.87, 18.6 282.22, 74.99 -51.1, -37.8 in-in in 7.5451 Saltbr-in 2.7085 HRD-in -76.97, -51.62 77.21, 8.56 in-in-none SNCiin in-none ActLoopNT-in 2.7568 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 130.97 APE9-dihe-in -105.16, 150.45 APE8-dihe-in -79.13, 89.35 APE8-rot-na 33.14 APE67-dihe-in -76.14, -3.82 -57.76, -35.85 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.6293 APE9-dist-in 6.7039 None None None XRAY 2.0 0.236 0.29 B 294.0 288.0 3 31 28 3 [[521, 779], [822, 1097]] 2.0 6glb Homo sapiens TYR_JAK3-2_HUMAN TYR 4e-80 274.8 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

Ligand: F48

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name