Ligand: EVC

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6LVKA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6LVKA P21802 468 766 821.0 EVC:801 Type1 Inactive DFGin 6.619 14.543 BLAminus -141.93, -174.02 55.34, 76.62 -90.82, 24.34 285.38, 77.37 -62.85, -30.59 in-in in 7.73 Saltbr-in 2.684 HRD-in -81.18, -49.18 75.66, -4.17 in-in-out SNCiio in-out ActLoopNT-in 2.796 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.17, 17.9 APE9-dihe-in -89.66, 132.44 APE8-dihe-in -56.46, 117.97 APE8-rot-na 336.42 APE67-dihe-in -71.4, -11.53 -57.14, -41.35 APE12-dist-na 10.045 APE11-dist-na 10.809 APE10-dist-na 7.443 APE9-dist-in 4.936 None PTR561 PTR561 XRAY 2.29 0.206 0.247 A 313 288 11 0 0 0 [[481, 759]] 1.0 6lvk TYR_FGFR2_HUMAN TYR 2.5e-104 354.1 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6LVKB P21802 468 765 821.0 EVC:801 Type1 Inactive DFGin 6.424 14.429 BLAminus -142.63, -167.55 46.22, 79.21 -86.53, 20.35 286.19, 75.54 -62.27, -23.76 in-in in 7.449 Saltbr-in 2.644 HRD-in -74.06, -49.98 75.98, -4.75 in-in-out SNCiio in-out ActLoopNT-in 2.806 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.0, 16.4 APE9-dihe-in -92.04, 132.11 APE8-dihe-in -55.72, 122.03 APE8-rot-na 331.04 APE67-dihe-in -82.5, -6.39 -64.61, -25.66 APE12-dist-na 10.161 APE11-dist-na 10.85 APE10-dist-na 7.496 APE9-dist-in 4.862 None PTR561 PTR561 XRAY 2.29 0.206 0.247 B 313 286 12 0 0 0 [[481, 759]] 1.0 6lvk TYR_FGFR2_HUMAN TYR 2.5e-104 354.1 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: EVC

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6LVKA

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 6LVKA P21802 468 766 821.0 EVC:801 Type1 Inactive DFGin 6.619 14.543 BLAminus -141.93, -174.02 55.34, 76.62 -90.82, 24.34 285.38, 77.37 -62.85, -30.59 in-in in 7.73 Saltbr-in 2.684 HRD-in -81.18, -49.18 75.66, -4.17 in-in-out SNCiio in-out ActLoopNT-in 2.796 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -115.17, 17.9 APE9-dihe-in -89.66, 132.44 APE8-dihe-in -56.46, 117.97 APE8-rot-na 336.42 APE67-dihe-in -71.4, -11.53 -57.14, -41.35 APE12-dist-na 10.045 APE11-dist-na 10.809 APE10-dist-na 7.443 APE9-dist-in 4.936 None PTR561 PTR561 XRAY 2.29 0.206 0.247 A 313 288 11 0 0 0 [[481, 759]] 1.0 6lvk Homo sapiens TYR_FGFR2_HUMAN TYR 2.5e-104 354.1 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 6LVKB P21802 468 765 821.0 EVC:801 Type1 Inactive DFGin 6.424 14.429 BLAminus -142.63, -167.55 46.22, 79.21 -86.53, 20.35 286.19, 75.54 -62.27, -23.76 in-in in 7.449 Saltbr-in 2.644 HRD-in -74.06, -49.98 75.98, -4.75 in-in-out SNCiio in-out ActLoopNT-in 2.806 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -116.0, 16.4 APE9-dihe-in -92.04, 132.11 APE8-dihe-in -55.72, 122.03 APE8-rot-na 331.04 APE67-dihe-in -82.5, -6.39 -64.61, -25.66 APE12-dist-na 10.161 APE11-dist-na 10.85 APE10-dist-na 7.496 APE9-dist-in 4.862 None PTR561 PTR561 XRAY 2.29 0.206 0.247 B 313 286 12 0 0 0 [[481, 759]] 1.0 6lvk Homo sapiens TYR_FGFR2_HUMAN TYR 2.5e-104 354.1 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

Ligand: EVC

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name