Ligand: EHB

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ANQA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 3ANQA Q13627 134 481 763.0 EHB:1 Type1 Inactive DFGin 7.428 15.033 BLAminus -121.67, -179.92 58.78, 88.75 -108.07, 22.93 278.63, 78.12 -73.99, -18.87 in-in in 8.689 Saltbr-in 2.68 HRD-in -53.82, -46.32 72.12, 1.71 in-in-out SNCiio in-out ActLoopNT-in 2.676 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -134.05, 156.97 APE9-dihe-na 80.08, 156.96 APE8-dihe-in -74.85, 138.03 APE8-rot-in 277.08 APE67-dihe-in -54.91, -29.37 -41.62, -56.78 APE12-dist-in 13.847 APE11-dist-in 11.843 APE10-dist-out 8.098 APE9-dist-in 3.321 None PTR321 PTR321 XRAY 2.6 0.236 0.27 A 368 343 5 0 0 0 [[159, 479]] 1.0 3anq CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANQB Q13627 133 481 763.0 EHB:1 Type1 Inactive DFGin 7.435 15.059 BLAminus -120.5, 177.48 60.82, 88.34 -107.39, 25.34 279.32, 79.44 -76.35, -18.64 in-in in 8.777 Saltbr-in 2.628 HRD-in -52.09, -40.38 68.1, -0.17 in-in-out SNCiio in-out ActLoopNT-in 3.565 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -110.82, 170.49 APE9-dihe-na 72.23, 154.86 APE8-dihe-in -73.28, 139.58 APE8-rot-in 273.53 APE67-dihe-in -54.53, -27.07 -43.45, -57.9 APE12-dist-out 14.259 APE11-dist-in 12.132 APE10-dist-out 8.046 APE9-dist-in 3.354 None PTR321 PTR321 XRAY 2.6 0.236 0.27 B 368 344 5 0 0 0 [[159, 479]] 1.0 3anq CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANQC Q13627 134 481 763.0 EHB:1 Type1 Inactive DFGin 7.463 15.221 BLAminus -119.05, 176.81 62.43, 87.36 -107.94, 27.53 279.33, 76.42 -77.11, -19.63 in-in in 8.714 Saltbr-in 2.613 HRD-in -51.7, -39.15 66.16, -1.22 in-in-out SNCiio in-out ActLoopNT-in 3.544 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -111.74, 164.15 APE9-dihe-na 79.15, 156.09 APE8-dihe-in -74.1, 139.85 APE8-rot-in 275.2 APE67-dihe-in -53.52, -28.49 -43.27, -57.57 APE12-dist-in 13.925 APE11-dist-in 12.218 APE10-dist-out 8.167 APE9-dist-in 3.38 None PTR321 PTR321 XRAY 2.6 0.236 0.27 C 368 341 7 0 0 0 [[159, 479]] 1.0 3anq CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANQD Q13627 136 479 763.0 EHB:1 Type1 Inactive DFGin 7.594 15.139 BLAminus -117.59, 176.99 61.44, 86.46 -106.43, 25.3 279.19, 78.64 -77.29, -17.82 in-in in 8.733 Saltbr-in 2.587 HRD-in -55.98, -44.97 70.33, -1.13 in-in-out SNCiio in-out ActLoopNT-in 3.321 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -131.55, 165.5 APE9-dihe-na 73.05, 156.06 APE8-dihe-in -74.09, 138.2 APE8-rot-in 274.37 APE67-dihe-in -57.04, -27.51 -41.5, -55.11 APE12-dist-in 13.917 APE11-dist-in 12.097 APE10-dist-out 8.168 APE9-dist-in 3.283 None PTR321 PTR321 XRAY 2.6 0.236 0.27 D 368 335 9 0 0 0 [[159, 479]] 1.0 3anq CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: EHB

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ANQA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 3ANQA Q13627 134 481 763.0 EHB:1 Type1 Inactive DFGin 7.428 15.033 BLAminus -121.67, -179.92 58.78, 88.75 -108.07, 22.93 278.63, 78.12 -73.99, -18.87 in-in in 8.689 Saltbr-in 2.68 HRD-in -53.82, -46.32 72.12, 1.71 in-in-out SNCiio in-out ActLoopNT-in 2.676 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -134.05, 156.97 APE9-dihe-na 80.08, 156.96 APE8-dihe-in -74.85, 138.03 APE8-rot-in 277.08 APE67-dihe-in -54.91, -29.37 -41.62, -56.78 APE12-dist-in 13.847 APE11-dist-in 11.843 APE10-dist-out 8.098 APE9-dist-in 3.321 None PTR321 PTR321 XRAY 2.6 0.236 0.27 A 368 343 5 0 0 0 [[159, 479]] 1.0 3anq Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANQB Q13627 133 481 763.0 EHB:1 Type1 Inactive DFGin 7.435 15.059 BLAminus -120.5, 177.48 60.82, 88.34 -107.39, 25.34 279.32, 79.44 -76.35, -18.64 in-in in 8.777 Saltbr-in 2.628 HRD-in -52.09, -40.38 68.1, -0.17 in-in-out SNCiio in-out ActLoopNT-in 3.565 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -110.82, 170.49 APE9-dihe-na 72.23, 154.86 APE8-dihe-in -73.28, 139.58 APE8-rot-in 273.53 APE67-dihe-in -54.53, -27.07 -43.45, -57.9 APE12-dist-out 14.259 APE11-dist-in 12.132 APE10-dist-out 8.046 APE9-dist-in 3.354 None PTR321 PTR321 XRAY 2.6 0.236 0.27 B 368 344 5 0 0 0 [[159, 479]] 1.0 3anq Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANQC Q13627 134 481 763.0 EHB:1 Type1 Inactive DFGin 7.463 15.221 BLAminus -119.05, 176.81 62.43, 87.36 -107.94, 27.53 279.33, 76.42 -77.11, -19.63 in-in in 8.714 Saltbr-in 2.613 HRD-in -51.7, -39.15 66.16, -1.22 in-in-out SNCiio in-out ActLoopNT-in 3.544 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -111.74, 164.15 APE9-dihe-na 79.15, 156.09 APE8-dihe-in -74.1, 139.85 APE8-rot-in 275.2 APE67-dihe-in -53.52, -28.49 -43.27, -57.57 APE12-dist-in 13.925 APE11-dist-in 12.218 APE10-dist-out 8.167 APE9-dist-in 3.38 None PTR321 PTR321 XRAY 2.6 0.236 0.27 C 368 341 7 0 0 0 [[159, 479]] 1.0 3anq Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANQD Q13627 136 479 763.0 EHB:1 Type1 Inactive DFGin 7.594 15.139 BLAminus -117.59, 176.99 61.44, 86.46 -106.43, 25.3 279.19, 78.64 -77.29, -17.82 in-in in 8.733 Saltbr-in 2.587 HRD-in -55.98, -44.97 70.33, -1.13 in-in-out SNCiio in-out ActLoopNT-in 3.321 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -131.55, 165.5 APE9-dihe-na 73.05, 156.06 APE8-dihe-in -74.09, 138.2 APE8-rot-in 274.37 APE67-dihe-in -57.04, -27.51 -41.5, -55.11 APE12-dist-in 13.917 APE11-dist-in 12.097 APE10-dist-out 8.168 APE9-dist-in 3.283 None PTR321 PTR321 XRAY 2.6 0.236 0.27 D 368 335 9 0 0 0 [[159, 479]] 1.0 3anq Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1 301 301 306 307 308 310 312 188 203 207 284 286 285 287 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: EHB

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name