Ligand: E6W

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6FT9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6FT9A P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.2322 14.2998 BLAminus -125.02, 175.42 67.64, 86.22 -106.42, 22.86 292.22, 81.03 -75.21, -13.41 in-in in 8.4297 Saltbr-in 2.7125 HRD-in -69.31, -51.72 79.55, -13.59 in-in-in SNCiii in-in ActLoopNT-in 2.8663 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.87, 168.01 APE9-dihe-na 73.7, 150.41 APE8-dihe-in -70.08, 140.16 APE8-rot-in 296.52 APE67-dihe-in -66.14, -21.84 -44.66, -47.8 APE12-dist-in 13.556 APE11-dist-in 11.2182 APE10-dist-in 7.2792 APE9-dist-in 2.9326 None None None XRAY 1.87 0.168 0.202 A 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6ft9 CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9B P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.2936 14.3139 BLAminus -123.52, 178.1 65.34, 85.29 -106.33, 21.22 292.88, 84.42 -75.16, -8.95 in-in in 8.4862 Saltbr-in 2.7077 HRD-in -71.01, -50.08 80.37, -13.57 in-in-in SNCiii in-in ActLoopNT-in 2.834 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.43, 168.15 APE9-dihe-na 75.76, 149.1 APE8-dihe-in -68.06, 138.01 APE8-rot-in 296.86 APE67-dihe-in -65.44, -22.15 -43.68, -46.72 APE12-dist-in 13.7449 APE11-dist-in 11.2771 APE10-dist-in 7.2841 APE9-dist-in 2.9662 None None None XRAY 1.87 0.168 0.202 B 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6ft9 CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9C P49759 148 482 484.0 E6W:60501 Type1 Inactive DFGin 7.2141 14.2533 BLAminus -122.85, 177.29 65.92, 85.07 -105.77, 22.23 295.06, 82.45 -71.81, -8.98 in-in in 8.3694 Saltbr-in 2.6709 HRD-in -69.43, -51.23 80.08, -14.43 in-in-out SNCiio in-out ActLoopNT-in 2.8644 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -129.97, 131.35 APE9-dihe-na -47.51, 149.39 APE8-dihe-in -75.79, 135.36 APE8-rot-in 303.89 APE67-dihe-out -54.68, -26.4 -154.15, 148.3 APE12-dist-out 14.7393 APE11-dist-in 12.4265 APE10-dist-out 9.6939 APE9-dist-out 8.7023 None None None XRAY 1.87 0.168 0.202 C 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6ft9 CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: E6W

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6FT9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6FT9A P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.2322 14.2998 BLAminus -125.02, 175.42 67.64, 86.22 -106.42, 22.86 292.22, 81.03 -75.21, -13.41 in-in in 8.4297 Saltbr-in 2.7125 HRD-in -69.31, -51.72 79.55, -13.59 in-in-in SNCiii in-in ActLoopNT-in 2.8663 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.87, 168.01 APE9-dihe-na 73.7, 150.41 APE8-dihe-in -70.08, 140.16 APE8-rot-in 296.52 APE67-dihe-in -66.14, -21.84 -44.66, -47.8 APE12-dist-in 13.556 APE11-dist-in 11.2182 APE10-dist-in 7.2792 APE9-dist-in 2.9326 None None None XRAY 1.87 0.168 0.202 A 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6ft9 Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9B P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.2936 14.3139 BLAminus -123.52, 178.1 65.34, 85.29 -106.33, 21.22 292.88, 84.42 -75.16, -8.95 in-in in 8.4862 Saltbr-in 2.7077 HRD-in -71.01, -50.08 80.37, -13.57 in-in-in SNCiii in-in ActLoopNT-in 2.834 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.43, 168.15 APE9-dihe-na 75.76, 149.1 APE8-dihe-in -68.06, 138.01 APE8-rot-in 296.86 APE67-dihe-in -65.44, -22.15 -43.68, -46.72 APE12-dist-in 13.7449 APE11-dist-in 11.2771 APE10-dist-in 7.2841 APE9-dist-in 2.9662 None None None XRAY 1.87 0.168 0.202 B 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6ft9 Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9C P49759 148 482 484.0 E6W:60501 Type1 Inactive DFGin 7.2141 14.2533 BLAminus -122.85, 177.29 65.92, 85.07 -105.77, 22.23 295.06, 82.45 -71.81, -8.98 in-in in 8.3694 Saltbr-in 2.6709 HRD-in -69.43, -51.23 80.08, -14.43 in-in-out SNCiio in-out ActLoopNT-in 2.8644 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -129.97, 131.35 APE9-dihe-na -47.51, 149.39 APE8-dihe-in -75.79, 135.36 APE8-rot-in 303.89 APE67-dihe-out -54.68, -26.4 -154.15, 148.3 APE12-dist-out 14.7393 APE11-dist-in 12.4265 APE10-dist-out 9.6939 APE9-dist-out 8.7023 None None None XRAY 1.87 0.168 0.202 C 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 6ft9 Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: E6W

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name