Ligand: E6W

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6FT9A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6FT9A P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.232 14.3 BLAminus -125.02, 175.42 67.64, 86.22 -106.42, 22.86 292.22, 81.03 -75.21, -13.41 in-in in 8.43 Saltbr-in 2.712 HRD-in -69.31, -51.72 79.55, -13.59 in-in-in SNCiii in-in ActLoopNT-in 2.866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.87, 168.01 APE9-dihe-na 73.7, 150.41 APE8-dihe-in -70.08, 140.16 APE8-rot-in 296.52 APE67-dihe-in -66.14, -21.84 -44.66, -47.8 APE12-dist-in 13.556 APE11-dist-in 11.218 APE10-dist-in 7.279 APE9-dist-in 2.933 None None None XRAY 1.87 0.168 0.202 A 339 335 0 0 0 0 [[161, 477]] 1.0 6ft9 CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9B P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.294 14.314 BLAminus -123.52, 178.1 65.34, 85.29 -106.33, 21.22 292.88, 84.42 -75.16, -8.95 in-in in 8.486 Saltbr-in 2.708 HRD-in -71.01, -50.08 80.37, -13.57 in-in-in SNCiii in-in ActLoopNT-in 2.834 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.43, 168.15 APE9-dihe-na 75.76, 149.1 APE8-dihe-in -68.06, 138.01 APE8-rot-in 296.86 APE67-dihe-in -65.44, -22.15 -43.68, -46.72 APE12-dist-in 13.745 APE11-dist-in 11.277 APE10-dist-in 7.284 APE9-dist-in 2.966 None None None XRAY 1.87 0.168 0.202 B 339 335 0 0 0 0 [[161, 477]] 1.0 6ft9 CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9C P49759 148 482 484.0 E6W:60501 Type1 Inactive DFGin 7.214 14.253 BLAminus -122.85, 177.29 65.92, 85.07 -105.77, 22.23 295.06, 82.45 -71.81, -8.98 in-in in 8.369 Saltbr-in 2.671 HRD-in -69.43, -51.23 80.08, -14.43 in-in-out SNCiio in-out ActLoopNT-in 2.864 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -129.97, 131.35 APE9-dihe-na -47.51, 149.39 APE8-dihe-in -75.79, 135.36 APE8-rot-in 303.89 APE67-dihe-out -54.68, -26.4 -154.15, 148.3 APE12-dist-out 14.739 APE11-dist-in 12.427 APE10-dist-out 9.694 APE9-dist-out 8.702 None None None XRAY 1.87 0.168 0.202 C 339 335 0 0 0 0 [[161, 477]] 1.0 6ft9 CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: E6W

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 6FT9A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 6FT9A P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.232 14.3 BLAminus -125.02, 175.42 67.64, 86.22 -106.42, 22.86 292.22, 81.03 -75.21, -13.41 in-in in 8.43 Saltbr-in 2.712 HRD-in -69.31, -51.72 79.55, -13.59 in-in-in SNCiii in-in ActLoopNT-in 2.866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.87, 168.01 APE9-dihe-na 73.7, 150.41 APE8-dihe-in -70.08, 140.16 APE8-rot-in 296.52 APE67-dihe-in -66.14, -21.84 -44.66, -47.8 APE12-dist-in 13.556 APE11-dist-in 11.218 APE10-dist-in 7.279 APE9-dist-in 2.933 None None None XRAY 1.87 0.168 0.202 A 339 335 0 0 0 0 [[161, 477]] 1.0 6ft9 Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9B P49759 148 482 484.0 E6W:60501 Type1 Active DFGin 7.294 14.314 BLAminus -123.52, 178.1 65.34, 85.29 -106.33, 21.22 292.88, 84.42 -75.16, -8.95 in-in in 8.486 Saltbr-in 2.708 HRD-in -71.01, -50.08 80.37, -13.57 in-in-in SNCiii in-in ActLoopNT-in 2.834 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.43, 168.15 APE9-dihe-na 75.76, 149.1 APE8-dihe-in -68.06, 138.01 APE8-rot-in 296.86 APE67-dihe-in -65.44, -22.15 -43.68, -46.72 APE12-dist-in 13.745 APE11-dist-in 11.277 APE10-dist-in 7.284 APE9-dist-in 2.966 None None None XRAY 1.87 0.168 0.202 B 339 335 0 0 0 0 [[161, 477]] 1.0 6ft9 Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 6FT9C P49759 148 482 484.0 E6W:60501 Type1 Inactive DFGin 7.214 14.253 BLAminus -122.85, 177.29 65.92, 85.07 -105.77, 22.23 295.06, 82.45 -71.81, -8.98 in-in in 8.369 Saltbr-in 2.671 HRD-in -69.43, -51.23 80.08, -14.43 in-in-out SNCiio in-out ActLoopNT-in 2.864 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -129.97, 131.35 APE9-dihe-na -47.51, 149.39 APE8-dihe-in -75.79, 135.36 APE8-rot-in 303.89 APE67-dihe-out -54.68, -26.4 -154.15, 148.3 APE12-dist-out 14.739 APE11-dist-in 12.427 APE10-dist-out 9.694 APE9-dist-out 8.702 None None None XRAY 1.87 0.168 0.202 C 339 335 0 0 0 0 [[161, 477]] 1.0 6ft9 Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: E6W

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name