Ligand: E1D

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6BP0D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6BP0B Q99986 23 341 396.0 E1D:404 Type1 Inactive DFGin 8.3965 14.4368 BLAminus -117.24, 179.69 62.15, 74.56 -92.04, 17.43 300.07, 74.46 -60.36, -36.15 in-in in 7.7794 Saltbr-in 2.655 HRD-in -91.52, -43.82 71.22, 1.27 in-in-out SNCiio in-out ActLoopNT-in 2.9707 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -62.38, 155.05 APE9-dihe-na 100.06, -162.09 APE8-dihe-in -99.16, 118.44 APE8-rot-in 302.05 APE67-dihe-in -65.07, -29.6 -53.14, -44.01 APE12-dist-out 15.3321 APE11-dist-in 13.8484 APE10-dist-out 8.0565 APE9-dist-in 4.1457 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.9 0.189 0.226 B 364.0 304.0 15 35 35 0 [[37, 326]] 1.0 6bp0 CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BP0D Q99986 22 341 396.0 E1D:406 Type1.5_Back Inactive DFGin 8.1889 14.4747 BLAminus -115.22, -179.95 61.34, 74.16 -89.56, 23.36 297.06, 72.1 -59.99, -33.49 in-in in 7.7226 Saltbr-in 2.8372 HRD-in -86.99, -45.85 73.72, 1.65 in-in-out SNCiio in-out ActLoopNT-in 2.9493 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -63.77, 154.43 APE9-dihe-na 102.07, -167.43 APE8-dihe-in -92.02, 120.13 APE8-rot-in 298.41 APE67-dihe-in -67.53, -26.8 -52.54, -44.24 APE12-dist-out 14.8303 APE11-dist-in 13.3247 APE10-dist-in 7.5046 APE9-dist-in 4.0751 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.9 0.189 0.226 D 364.0 311.0 9 35 35 0 [[37, 326]] 1.0 6bp0 CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

Ligand: E1D

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6BP0D
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CK1 VRK1 VRK1_HUMAN 6BP0B Q99986 23 341 396.0 E1D:404 Type1 Inactive DFGin 8.3965 14.4368 BLAminus -117.24, 179.69 62.15, 74.56 -92.04, 17.43 300.07, 74.46 -60.36, -36.15 in-in in 7.7794 Saltbr-in 2.655 HRD-in -91.52, -43.82 71.22, 1.27 in-in-out SNCiio in-out ActLoopNT-in 2.9707 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -62.38, 155.05 APE9-dihe-na 100.06, -162.09 APE8-dihe-in -99.16, 118.44 APE8-rot-in 302.05 APE67-dihe-in -65.07, -29.6 -53.14, -44.01 APE12-dist-out 15.3321 APE11-dist-in 13.8484 APE10-dist-out 8.0565 APE9-dist-in 4.1457 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.9 0.189 0.226 B 364.0 304.0 15 35 35 0 [[37, 326]] 1.0 6bp0 Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1
CK1 VRK1 VRK1_HUMAN 6BP0D Q99986 22 341 396.0 E1D:406 Type1.5_Back Inactive DFGin 8.1889 14.4747 BLAminus -115.22, -179.95 61.34, 74.16 -89.56, 23.36 297.06, 72.1 -59.99, -33.49 in-in in 7.7226 Saltbr-in 2.8372 HRD-in -86.99, -45.85 73.72, 1.65 in-in-out SNCiio in-out ActLoopNT-in 2.9493 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oiii APE10-dihe-na -63.77, 154.43 APE9-dihe-na 102.07, -167.43 APE8-dihe-in -92.02, 120.13 APE8-rot-in 298.41 APE67-dihe-in -67.53, -26.8 -52.54, -44.24 APE12-dist-out 14.8303 APE11-dist-in 13.3247 APE10-dist-in 7.5046 APE9-dist-in 4.0751 K34A,K35A,E36A,E212A,K214A,E215A,E292A,K293A,K295A,K359A,K360A None None XRAY 1.9 0.189 0.226 D 364.0 311.0 9 35 35 0 [[37, 326]] 1.0 6bp0 Homo sapiens CK1_VRK1_HUMAN CK1 8.4e-105 355.8 1.0 261.0 261.0 196 197 198 200 202 71 83 87 174 176 175 177.0 243 231 226 225 224 223 222 221 220 132 Serine/threonine-protein kinase VRK1

Ligand: E1D

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name