Ligand: DX4

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name

Ligand: DX4

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4XP3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_RAT 4XOYA P63086 9 353 358.0 DX4:401 Type1 Inactive DFGin 6.8384 16.4726 BLAminus -133.37, 174.39 67.24, 87.56 -100.05, 25.74 287.52, 74.09 -60.62, -29.03 out-out out 10.1548 Saltbr-out 6.1211 HRD-in -76.12, -52.95 76.38, -1.71 out-in-none SNCoin in-none ActLoopNT-in 2.7547 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 175.0 APE8-dihe-in -56.7, 130.92 APE8-rot-in 317.45 APE67-dihe-in -61.42, -22.5 -58.06, -51.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.6184 None None CME125,CME159,CME164,CME252 XRAY 2.1 0.182 0.218 A 351.0 330.0 8 31 28 3 [[23, 311]] 1.0 4xoy Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_RAT 4XP3A P63086 8 354 358.0 DX4:401 Type1 Inactive DFGin 6.6537 16.0826 BLAminus -130.71, 174.0 60.88, 94.31 -106.94, 16.18 286.8, 78.81 -56.37, -28.23 in-out in 9.2564 Saltbr-out 5.2988 HRD-in -68.04, -51.13 71.44, 6.73 out-in-out SNCoio in-out ActLoopNT-in 2.821 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -121.82, 140.79 APE9-dihe-na 65.58, 179.47 APE8-dihe-in -91.24, 138.76 APE8-rot-in 296.06 APE67-dihe-in -60.07, -19.89 -42.76, -56.06 APE12-dist-in 13.6573 APE11-dist-in 11.2991 APE10-dist-out 9.0284 APE9-dist-in 3.1168 None None CME159,CME252 XRAY 1.782 0.15 0.179 A 351.0 341.0 0 31 31 0 [[23, 311]] 1.0 4xp3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1

Ligand: DX4

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4XP3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_RAT 4XOYA P63086 9 353 358.0 DX4:401 Type1 Inactive DFGin 6.8384 16.4726 BLAminus -133.37, 174.39 67.24, 87.56 -100.05, 25.74 287.52, 74.09 -60.62, -29.03 out-out out 10.1548 Saltbr-out 6.1211 HRD-in -76.12, -52.95 76.38, -1.71 out-in-none SNCoin in-none ActLoopNT-in 2.7547 ActLoopCT-none nonTYR APEdihe_aaiii APEdist_nnni APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 175.0 APE8-dihe-in -56.7, 130.92 APE8-rot-in 317.45 APE67-dihe-in -61.42, -22.5 -58.06, -51.04 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-in 4.6184 None None CME125,CME159,CME164,CME252 XRAY 2.1 0.182 0.218 A 351.0 330.0 8 31 28 3 [[23, 311]] 1.0 4xoy Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_RAT 4XP3A P63086 8 354 358.0 DX4:401 Type1 Inactive DFGin 6.6537 16.0826 BLAminus -130.71, 174.0 60.88, 94.31 -106.94, 16.18 286.8, 78.81 -56.37, -28.23 in-out in 9.2564 Saltbr-out 5.2988 HRD-in -68.04, -51.13 71.44, 6.73 out-in-out SNCoio in-out ActLoopNT-in 2.821 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -121.82, 140.79 APE9-dihe-na 65.58, 179.47 APE8-dihe-in -91.24, 138.76 APE8-rot-in 296.06 APE67-dihe-in -60.07, -19.89 -42.76, -56.06 APE12-dist-in 13.6573 APE11-dist-in 11.2991 APE10-dist-out 9.0284 APE9-dist-in 3.1168 None None CME159,CME252 XRAY 1.782 0.15 0.179 A 351.0 341.0 0 31 31 0 [[23, 311]] 1.0 4xp3 Rattus norvegicus CMGC_MAPK1_RAT CMGC 1.2e-85 293.3 1.0 301.0 301.0 164 165 166 168 170 52 69 73 144 146 145 147.0 208 195 190 189 188 187 186 185 184 104 Mitogen-activated protein kinase 1