Ligand: CMG

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 1H1PA
DFGin BLBtrans 1 33.3% 1E1VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1H1PA P24941 1 296 298.0 CMG:61298 Type1 Active DFGin 6.4993 15.1175 BLAminus -138.92, -178.75 49.09, 86.95 -98.56, 13.99 278.53, 73.35 -55.78, -28.79 in-in in 8.4539 Saltbr-in 2.7215 HRD-in -77.48, -54.23 72.33, 13.84 in-in-in SNCiii in-in ActLoopNT-in 2.8866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.77, 156.24 APE9-dihe-na 69.07, 128.03 APE8-dihe-in -49.71, 132.1 APE8-rot-in 291.9 APE67-dihe-in -61.95, -27.18 -48.08, -36.47 APE12-dist-in 13.0523 APE11-dist-in 10.0523 APE10-dist-in 7.2348 APE9-dist-in 3.1622 None TPO160 TPO160 XRAY 2.1 0.222 0.258 A 303.0 296.0 0 28 28 0 [[4, 286]] 1.0 1h1p CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1H1PC P24941 1 296 298.0 CMG:61298 Type1 Active DFGin 6.5662 15.1531 BLAminus -139.68, 176.89 52.0, 85.54 -98.31, 22.42 285.04, 73.37 -70.33, -22.32 in-in in 8.5886 Saltbr-in 2.7814 HRD-in -79.75, -57.12 71.34, 16.79 in-in-in SNCiii in-in ActLoopNT-in 2.9334 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.98, 156.69 APE9-dihe-na 68.49, 129.02 APE8-dihe-in -58.75, 132.04 APE8-rot-in 288.32 APE67-dihe-in -70.71, -22.16 -48.03, -37.61 APE12-dist-in 12.8769 APE11-dist-in 9.8883 APE10-dist-in 7.2536 APE9-dist-in 3.2408 None TPO160 TPO160 XRAY 2.1 0.222 0.258 C 303.0 296.0 0 28 28 0 [[4, 286]] 1.0 1h1p CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1E1VA P24941 1 298 298.0 CMG:60401 Type1 Inactive DFGin 10.7004 18.0462 BLBtrans -99.24, 155.81 66.87, 24.14 -63.76, 132.18 229.6, 99.82 83.4, -10.92 out-out out 14.7912 Saltbr-out 16.8327 HRD-in -80.59, -61.19 86.42, -5.25 out-out-out SNCooo out-out ActLoopNT-out 5.8882 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -81.29, 122.71 APE9-dihe-na -66.44, 133.05 APE8-dihe-in -66.6, 142.89 APE8-rot-out 188.61 APE67-dihe-in -57.66, -27.27 -107.35, -0.77 APE12-dist-out 20.1277 APE11-dist-out 17.3419 APE10-dist-out 18.8329 APE9-dist-out 10.2538 None None None XRAY 1.95 0.195 0.269 A 299.0 290.0 8 28 28 0 [[4, 286]] 1.0 1e1v CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: CMG

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 1H1PA
DFGin BLBtrans 1 33.3% 1E1VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1H1PA P24941 1 296 298.0 CMG:61298 Type1 Active DFGin 6.4993 15.1175 BLAminus -138.92, -178.75 49.09, 86.95 -98.56, 13.99 278.53, 73.35 -55.78, -28.79 in-in in 8.4539 Saltbr-in 2.7215 HRD-in -77.48, -54.23 72.33, 13.84 in-in-in SNCiii in-in ActLoopNT-in 2.8866 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -140.77, 156.24 APE9-dihe-na 69.07, 128.03 APE8-dihe-in -49.71, 132.1 APE8-rot-in 291.9 APE67-dihe-in -61.95, -27.18 -48.08, -36.47 APE12-dist-in 13.0523 APE11-dist-in 10.0523 APE10-dist-in 7.2348 APE9-dist-in 3.1622 None TPO160 TPO160 XRAY 2.1 0.222 0.258 A 303.0 296.0 0 28 28 0 [[4, 286]] 1.0 1h1p Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1H1PC P24941 1 296 298.0 CMG:61298 Type1 Active DFGin 6.5662 15.1531 BLAminus -139.68, 176.89 52.0, 85.54 -98.31, 22.42 285.04, 73.37 -70.33, -22.32 in-in in 8.5886 Saltbr-in 2.7814 HRD-in -79.75, -57.12 71.34, 16.79 in-in-in SNCiii in-in ActLoopNT-in 2.9334 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.98, 156.69 APE9-dihe-na 68.49, 129.02 APE8-dihe-in -58.75, 132.04 APE8-rot-in 288.32 APE67-dihe-in -70.71, -22.16 -48.03, -37.61 APE12-dist-in 12.8769 APE11-dist-in 9.8883 APE10-dist-in 7.2536 APE9-dist-in 3.2408 None TPO160 TPO160 XRAY 2.1 0.222 0.258 C 303.0 296.0 0 28 28 0 [[4, 286]] 1.0 1h1p Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1E1VA P24941 1 298 298.0 CMG:60401 Type1 Inactive DFGin 10.7004 18.0462 BLBtrans -99.24, 155.81 66.87, 24.14 -63.76, 132.18 229.6, 99.82 83.4, -10.92 out-out out 14.7912 Saltbr-out 16.8327 HRD-in -80.59, -61.19 86.42, -5.25 out-out-out SNCooo out-out ActLoopNT-out 5.8882 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -81.29, 122.71 APE9-dihe-na -66.44, 133.05 APE8-dihe-in -66.6, 142.89 APE8-rot-out 188.61 APE67-dihe-in -57.66, -27.27 -107.35, -0.77 APE12-dist-out 20.1277 APE11-dist-out 17.3419 APE10-dist-out 18.8329 APE9-dist-out 10.2538 None None None XRAY 1.95 0.195 0.269 A 299.0 290.0 8 28 28 0 [[4, 286]] 1.0 1e1v Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: CMG

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name