Ligand: CK8

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 2C5NA
DFGin BLBtrans 1 33.3% 1PXPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2C5NA P24941 1 296 298.0 CK8:1297 Type1 Inactive DFGin 6.4617 15.3334 BLAminus -134.71, 179.52 48.73, 86.34 -97.55, 25.19 275.89, 67.63 -63.89, -28.59 in-in in 8.543 Saltbr-in 2.8605 HRD-in -83.74, -45.86 67.31, -5.85 in-in-out SNCiio in-out ActLoopNT-in 2.7927 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oioi APE10-dihe-na -100.4, 27.23 APE9-dihe-na -97.0, -7.31 APE8-dihe-out 101.7, 140.58 APE8-rot-out 225.76 APE67-dihe-in -62.0, -24.64 -95.08, -50.02 APE12-dist-out 14.2745 APE11-dist-in 11.4517 APE10-dist-out 8.9685 APE9-dist-in 5.2102 None None None XRAY 2.1 0.178 0.259 A 298.0 296.0 0 28 28 0 [[4, 286]] 1.0 2c5n CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5NC P24941 1 297 298.0 CK8:1298 Type1 Inactive DFGin 6.6301 15.4371 BLAminus -141.11, 171.58 67.92, 76.41 -96.67, 28.48 283.19, 65.37 -68.12, -31.46 in-in in 8.5548 Saltbr-in 2.6265 HRD-in -73.82, -54.83 87.12, -13.53 in-in-out SNCiio in-out ActLoopNT-in 2.9506 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -121.38, 99.53 APE9-dihe-na -160.5, -177.06 APE8-dihe-in -68.95, 135.12 APE8-rot-out 74.74 APE67-dihe-in -60.97, -29.13 -104.2, -8.66 APE12-dist-out 16.2911 APE11-dist-in 10.2609 APE10-dist-out 12.5251 APE9-dist-out 9.0451 None None None XRAY 2.1 0.178 0.259 C 298.0 297.0 0 28 28 0 [[4, 286]] 1.0 2c5n CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1PXPA P24941 1 298 298.0 CK8:500 Type1 Inactive DFGin 10.6034 17.7421 BLBtrans -113.05, 154.9 70.73, 32.65 -74.6, 130.58 226.9, 118.91 82.84, -5.59 out-out out 15.0619 Saltbr-out 15.8217 HRD-in -86.63, -50.87 79.85, -16.9 out-out-out SNCooo out-out ActLoopNT-out 5.7937 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -141.97, 139.84 APE9-dihe-na -79.23, 137.29 APE8-dihe-in -88.93, 135.37 APE8-rot-out 187.31 APE67-dihe-in -53.16, -23.41 -112.15, 2.68 APE12-dist-out 21.098 APE11-dist-out 18.4907 APE10-dist-out 19.3634 APE9-dist-out 10.9652 None None None XRAY 2.3 0.23 0.273 A 298.0 294.0 4 28 28 0 [[4, 286]] 1.0 1pxp CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: CK8

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 2C5NA
DFGin BLBtrans 1 33.3% 1PXPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2C5NA P24941 1 296 298.0 CK8:1297 Type1 Inactive DFGin 6.4617 15.3334 BLAminus -134.71, 179.52 48.73, 86.34 -97.55, 25.19 275.89, 67.63 -63.89, -28.59 in-in in 8.543 Saltbr-in 2.8605 HRD-in -83.74, -45.86 67.31, -5.85 in-in-out SNCiio in-out ActLoopNT-in 2.7927 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oioi APE10-dihe-na -100.4, 27.23 APE9-dihe-na -97.0, -7.31 APE8-dihe-out 101.7, 140.58 APE8-rot-out 225.76 APE67-dihe-in -62.0, -24.64 -95.08, -50.02 APE12-dist-out 14.2745 APE11-dist-in 11.4517 APE10-dist-out 8.9685 APE9-dist-in 5.2102 None None None XRAY 2.1 0.178 0.259 A 298.0 296.0 0 28 28 0 [[4, 286]] 1.0 2c5n Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C5NC P24941 1 297 298.0 CK8:1298 Type1 Inactive DFGin 6.6301 15.4371 BLAminus -141.11, 171.58 67.92, 76.41 -96.67, 28.48 283.19, 65.37 -68.12, -31.46 in-in in 8.5548 Saltbr-in 2.6265 HRD-in -73.82, -54.83 87.12, -13.53 in-in-out SNCiio in-out ActLoopNT-in 2.9506 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oioo APE10-dihe-na -121.38, 99.53 APE9-dihe-na -160.5, -177.06 APE8-dihe-in -68.95, 135.12 APE8-rot-out 74.74 APE67-dihe-in -60.97, -29.13 -104.2, -8.66 APE12-dist-out 16.2911 APE11-dist-in 10.2609 APE10-dist-out 12.5251 APE9-dist-out 9.0451 None None None XRAY 2.1 0.178 0.259 C 298.0 297.0 0 28 28 0 [[4, 286]] 1.0 2c5n Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1PXPA P24941 1 298 298.0 CK8:500 Type1 Inactive DFGin 10.6034 17.7421 BLBtrans -113.05, 154.9 70.73, 32.65 -74.6, 130.58 226.9, 118.91 82.84, -5.59 out-out out 15.0619 Saltbr-out 15.8217 HRD-in -86.63, -50.87 79.85, -16.9 out-out-out SNCooo out-out ActLoopNT-out 5.7937 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -141.97, 139.84 APE9-dihe-na -79.23, 137.29 APE8-dihe-in -88.93, 135.37 APE8-rot-out 187.31 APE67-dihe-in -53.16, -23.41 -112.15, 2.68 APE12-dist-out 21.098 APE11-dist-out 18.4907 APE10-dist-out 19.3634 APE9-dist-out 10.9652 None None None XRAY 2.3 0.23 0.273 A 298.0 294.0 4 28 28 0 [[4, 286]] 1.0 1pxp Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: CK8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name