Ligand: C95

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2UZEA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2UZEA P24941 1 296 298.0 C95:1297 Type1 Active DFGin 6.754 15.05 BLAminus -135.91, 179.99 53.98, 78.89 -93.27, 19.08 281.96, 77.01 -61.65, -33.72 in-in in 8.583 Saltbr-in 2.498 HRD-in -73.47, -51.79 67.24, 9.7 in-in-in SNCiii in-in ActLoopNT-in 2.835 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.88, 130.34 APE9-dihe-na 76.85, 131.74 APE8-dihe-in -52.05, 131.49 APE8-rot-in 297.06 APE67-dihe-in -66.18, -19.21 -44.9, -46.95 APE12-dist-in 13.145 APE11-dist-in 10.034 APE10-dist-in 7.852 APE9-dist-in 3.338 None TPO160 TPO160 XRAY 2.4 0.198 0.243 A 298 296 0 0 0 0 [[4, 286]] 1.0 2uze CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2UZEC P24941 1 297 298.0 C95:1297 Type1 Active DFGin 6.667 14.941 BLAminus -135.15, 177.98 57.61, 75.33 -89.15, 22.31 284.49, 74.72 -59.82, -39.09 in-in in 8.537 Saltbr-in 2.571 HRD-in -68.46, -55.91 69.02, 11.45 in-in-in SNCiii in-in ActLoopNT-in 2.842 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.35, 137.28 APE9-dihe-na 72.87, 131.3 APE8-dihe-in -52.65, 132.5 APE8-rot-in 295.51 APE67-dihe-in -60.05, -23.05 -45.59, -48.84 APE12-dist-in 13.108 APE11-dist-in 10.268 APE10-dist-in 7.788 APE9-dist-in 3.311 None TPO160 TPO160 XRAY 2.4 0.198 0.243 C 298 297 0 0 0 0 [[4, 286]] 1.0 2uze CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: C95

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2UZEA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2UZEA P24941 1 296 298.0 C95:1297 Type1 Active DFGin 6.754 15.05 BLAminus -135.91, 179.99 53.98, 78.89 -93.27, 19.08 281.96, 77.01 -61.65, -33.72 in-in in 8.583 Saltbr-in 2.498 HRD-in -73.47, -51.79 67.24, 9.7 in-in-in SNCiii in-in ActLoopNT-in 2.835 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.88, 130.34 APE9-dihe-na 76.85, 131.74 APE8-dihe-in -52.05, 131.49 APE8-rot-in 297.06 APE67-dihe-in -66.18, -19.21 -44.9, -46.95 APE12-dist-in 13.145 APE11-dist-in 10.034 APE10-dist-in 7.852 APE9-dist-in 3.338 None TPO160 TPO160 XRAY 2.4 0.198 0.243 A 298 296 0 0 0 0 [[4, 286]] 1.0 2uze Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2UZEC P24941 1 297 298.0 C95:1297 Type1 Active DFGin 6.667 14.941 BLAminus -135.15, 177.98 57.61, 75.33 -89.15, 22.31 284.49, 74.72 -59.82, -39.09 in-in in 8.537 Saltbr-in 2.571 HRD-in -68.46, -55.91 69.02, 11.45 in-in-in SNCiii in-in ActLoopNT-in 2.842 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.35, 137.28 APE9-dihe-na 72.87, 131.3 APE8-dihe-in -52.65, 132.5 APE8-rot-in 295.51 APE67-dihe-in -60.05, -23.05 -45.59, -48.84 APE12-dist-in 13.108 APE11-dist-in 10.268 APE10-dist-in 7.788 APE9-dist-in 3.311 None TPO160 TPO160 XRAY 2.4 0.198 0.243 C 298 297 0 0 0 0 [[4, 286]] 1.0 2uze Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: C95

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name