Ligand: BLZ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2I40C
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2I40A P24941 1 297 298.0 BLZ:301 Type1 Inactive DFGin 6.501 15.32 BLAminus -136.92, 178.32 54.65, 74.51 -89.47, 33.14 288.96, 69.44 -65.33, -27.4 in-in in 8.719 Saltbr-in 2.817 HRD-in -76.77, -57.06 80.86, -11.7 in-in-out SNCiio in-out ActLoopNT-in 2.789 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnii APE10-dihe-na 999.0, -92.23 APE9-dihe-na -60.69, 145.56 APE8-dihe-in -55.35, 148.14 APE8-rot-out 189.36 APE67-dihe-in -50.54, -27.99 -55.95, -51.36 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.458 APE9-dist-in 4.135 None None None XRAY 2.8 0.195 0.222 A 298 291 6 0 0 3 [[4, 286]] 1.0 2i40 CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2I40C P24941 1 296 298.0 BLZ:401 Type1 Inactive DFGin 6.5 15.684 BLAminus -135.33, 178.43 51.55, 77.51 -89.62, 25.76 284.58, 71.55 -62.03, -32.72 in-in in 8.887 Saltbr-in 2.947 HRD-in -75.92, -56.81 84.43, -19.08 in-in-out SNCiio in-out ActLoopNT-in 2.786 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -117.69, -26.4 APE9-dihe-na -42.35, 127.37 APE8-dihe-in -54.04, 136.23 APE8-rot-in 299.61 APE67-dihe-in -58.47, -31.19 -61.46, -43.46 APE12-dist-out 14.259 APE11-dist-in 12.034 APE10-dist-out 8.018 APE9-dist-in 4.557 None None None XRAY 2.8 0.195 0.222 C 298 296 0 0 0 0 [[4, 286]] 1.0 2i40 CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: BLZ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2I40C
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2I40A P24941 1 297 298.0 BLZ:301 Type1 Inactive DFGin 6.501 15.32 BLAminus -136.92, 178.32 54.65, 74.51 -89.47, 33.14 288.96, 69.44 -65.33, -27.4 in-in in 8.719 Saltbr-in 2.817 HRD-in -76.77, -57.06 80.86, -11.7 in-in-out SNCiio in-out ActLoopNT-in 2.789 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnii APE10-dihe-na 999.0, -92.23 APE9-dihe-na -60.69, 145.56 APE8-dihe-in -55.35, 148.14 APE8-rot-out 189.36 APE67-dihe-in -50.54, -27.99 -55.95, -51.36 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.458 APE9-dist-in 4.135 None None None XRAY 2.8 0.195 0.222 A 298 291 6 0 0 3 [[4, 286]] 1.0 2i40 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2I40C P24941 1 296 298.0 BLZ:401 Type1 Inactive DFGin 6.5 15.684 BLAminus -135.33, 178.43 51.55, 77.51 -89.62, 25.76 284.58, 71.55 -62.03, -32.72 in-in in 8.887 Saltbr-in 2.947 HRD-in -75.92, -56.81 84.43, -19.08 in-in-out SNCiio in-out ActLoopNT-in 2.786 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -117.69, -26.4 APE9-dihe-na -42.35, 127.37 APE8-dihe-in -54.04, 136.23 APE8-rot-in 299.61 APE67-dihe-in -58.47, -31.19 -61.46, -43.46 APE12-dist-out 14.259 APE11-dist-in 12.034 APE10-dist-out 8.018 APE9-dist-in 4.557 None None None XRAY 2.8 0.195 0.222 C 298 296 0 0 0 0 [[4, 286]] 1.0 2i40 Homo sapiens CMGC_CDK2_HUMAN CMGC 6.3e-90 307.9 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: BLZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name