Ligand: ACK

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2IVSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR RET RET_HUMAN 2IVSA P07949 713 1012 1114.0 ACK:63016 Type1 Inactive DFGin 6.7832 14.1793 BLAminus -136.62, -179.95 61.37, 73.3 -96.71, 13.54 284.89, 83.7 -58.31, -35.12 in-in in 6.8221 Saltbr-in 2.7237 HRD-in -73.32, -45.65 77.78, -26.26 in-in-out SNCiio in-out ActLoopNT-in 2.9021 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.12, 16.27 APE9-dihe-in -86.42, 135.65 APE8-dihe-in -50.22, 131.78 APE8-rot-na 326.77 APE67-dihe-in -68.23, -10.26 -49.69, -41.68 APE12-dist-na 13.4077 APE11-dist-na 9.1367 APE10-dist-na 7.3587 APE9-dist-in 5.361 None None None XRAY 2.0 0.183 0.229 A 314.0 284.0 16 30 30 0 [[724, 1007]] 1.0 2ivs TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2IVSB P07949 703 1012 1114.0 ACK:63016 Type1 Inactive DFGin 6.7805 14.5431 BLAminus -130.3, -178.58 63.6, 66.85 -91.03, 11.65 282.25, 80.2 -55.31, -31.74 in-in in 7.1739 Saltbr-in 2.8608 HRD-in -71.97, -42.82 73.93, -25.74 in-in-out SNCiio in-out ActLoopNT-in 2.8685 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.76, 9.86 APE9-dihe-in -84.11, 132.2 APE8-dihe-in -50.29, 130.93 APE8-rot-na 326.96 APE67-dihe-in -73.13, -10.63 -49.04, -38.94 APE12-dist-na 999.0 APE11-dist-na 9.2546 APE10-dist-na 7.2606 APE9-dist-in 5.3268 None None None XRAY 2.0 0.183 0.229 B 314.0 274.0 33 30 19 11 [[724, 1007]] 1.0 2ivs TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: ACK

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2IVSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR RET RET_HUMAN 2IVSA P07949 713 1012 1114.0 ACK:63016 Type1 Inactive DFGin 6.7832 14.1793 BLAminus -136.62, -179.95 61.37, 73.3 -96.71, 13.54 284.89, 83.7 -58.31, -35.12 in-in in 6.8221 Saltbr-in 2.7237 HRD-in -73.32, -45.65 77.78, -26.26 in-in-out SNCiio in-out ActLoopNT-in 2.9021 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -109.12, 16.27 APE9-dihe-in -86.42, 135.65 APE8-dihe-in -50.22, 131.78 APE8-rot-na 326.77 APE67-dihe-in -68.23, -10.26 -49.69, -41.68 APE12-dist-na 13.4077 APE11-dist-na 9.1367 APE10-dist-na 7.3587 APE9-dist-in 5.361 None None None XRAY 2.0 0.183 0.229 A 314.0 284.0 16 30 30 0 [[724, 1007]] 1.0 2ivs Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret
TYR RET RET_HUMAN 2IVSB P07949 703 1012 1114.0 ACK:63016 Type1 Inactive DFGin 6.7805 14.5431 BLAminus -130.3, -178.58 63.6, 66.85 -91.03, 11.65 282.25, 80.2 -55.31, -31.74 in-in in 7.1739 Saltbr-in 2.8608 HRD-in -71.97, -42.82 73.93, -25.74 in-in-out SNCiio in-out ActLoopNT-in 2.8685 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.76, 9.86 APE9-dihe-in -84.11, 132.2 APE8-dihe-in -50.29, 130.93 APE8-rot-na 326.96 APE67-dihe-in -73.13, -10.63 -49.04, -38.94 APE12-dist-na 999.0 APE11-dist-na 9.2546 APE10-dist-na 7.2606 APE9-dist-in 5.3268 None None None XRAY 2.0 0.183 0.229 B 314.0 274.0 33 30 19 11 [[724, 1007]] 1.0 2ivs Homo sapiens TYR_RET_HUMAN TYR 4.1e-101 343.6 1.0 261.0 261.0 891 892 893 895 897 758 775 779 871 873 872 874.0 933 921 916 915 914 913 912 911 910 805 Proto-oncogene tyrosine-protein kinase receptor Ret

Ligand: ACK

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name