Ligand: A1L53

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9KL4A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9KLWA P00533 696 1019 1210.0 A1L53:61101 Type1 None DFGin 5.3596 15.0162 BLAminus -137.92, -173.21 68.95, 86.53 -103.04, 23.39 302.9, 100.52 -66.02, -20.59 in-in in 8.7295 Saltbr-in 3.4098 HRD-in -69.44, -47.22 66.72, 12.67 in-in-none SNCiin in-none ActLoopNT-in 2.9383 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 149.08 APE8-dihe-in -82.92, 74.1 APE8-rot-na 34.98 APE67-dihe-in -75.3, -8.48 -60.53, -40.21 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.6898 T790M,L858R None None XRAY 2.67 0.2 0.257 A 330.0 298.0 14 30 17 13 [[712, 970]] 1.0 9klw TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9KL4A P00533 696 1019 1210.0 A1L53:1101 Type1 Active DFGin 5.8816 14.8735 BLAminus -137.95, -173.96 67.15, 83.4 -96.91, 17.41 294.77, 100.38 -52.64, -41.23 in-in in 8.6152 Saltbr-in 3.0856 HRD-in -70.73, -50.16 70.67, 8.63 in-in-in SNCiii in-in ActLoopNT-in 2.8668 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.29, 144.18 APE9-dihe-in -146.46, 153.32 APE8-dihe-in -90.55, 99.64 APE8-rot-na 31.82 APE67-dihe-in -68.73, -13.99 -62.45, -40.55 APE12-dist-na 11.6634 APE11-dist-na 9.8823 APE10-dist-na 10.6414 APE9-dist-in 6.8747 None None None XRAY 2.32 0.189 0.238 A 330.0 313.0 0 30 30 0 [[712, 970]] 1.0 9kl4 TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1L53

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9KL4A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9KLWA P00533 696 1019 1210.0 A1L53:61101 Type1 None DFGin 5.3596 15.0162 BLAminus -137.92, -173.21 68.95, 86.53 -103.04, 23.39 302.9, 100.52 -66.02, -20.59 in-in in 8.7295 Saltbr-in 3.4098 HRD-in -69.44, -47.22 66.72, 12.67 in-in-none SNCiin in-none ActLoopNT-in 2.9383 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 149.08 APE8-dihe-in -82.92, 74.1 APE8-rot-na 34.98 APE67-dihe-in -75.3, -8.48 -60.53, -40.21 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.6898 T790M,L858R None None XRAY 2.67 0.2 0.257 A 330.0 298.0 14 30 17 13 [[712, 970]] 1.0 9klw Homo sapiens TYR_EGFR_HUMAN TYR 8.6e-87 296.8 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9KL4A P00533 696 1019 1210.0 A1L53:1101 Type1 Active DFGin 5.8816 14.8735 BLAminus -137.95, -173.96 67.15, 83.4 -96.91, 17.41 294.77, 100.38 -52.64, -41.23 in-in in 8.6152 Saltbr-in 3.0856 HRD-in -70.73, -50.16 70.67, 8.63 in-in-in SNCiii in-in ActLoopNT-in 2.8668 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.29, 144.18 APE9-dihe-in -146.46, 153.32 APE8-dihe-in -90.55, 99.64 APE8-rot-na 31.82 APE67-dihe-in -68.73, -13.99 -62.45, -40.55 APE12-dist-na 11.6634 APE11-dist-na 9.8823 APE10-dist-na 10.6414 APE9-dist-in 6.8747 None None None XRAY 2.32 0.189 0.238 A 330.0 313.0 0 30 30 0 [[712, 970]] 1.0 9kl4 Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1L53

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name