Ligand: A1IMT

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9GL8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9GL9A P00533 696 1019 1210.0 A1IMT:61103 Type1.5_Back Active DFGin 6.134 14.3515 BLAminus -126.96, -175.87 60.02, 86.56 -97.41, 25.27 289.91, 91.21 -60.54, -33.98 in-in in 8.3689 Saltbr-in 2.9348 HRD-in -68.5, -49.91 70.75, -1.83 in-in-in SNCiii in-in ActLoopNT-in 2.8766 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.17, 127.77 APE9-dihe-in -129.15, 139.26 APE8-dihe-in -73.46, 89.68 APE8-rot-na 31.97 APE67-dihe-in -69.08, -6.41 -52.73, -42.79 APE12-dist-na 11.7681 APE11-dist-na 10.0478 APE10-dist-na 10.6342 APE9-dist-in 6.6861 None None None XRAY 2.147 0.198 0.213 A 330.0 313.0 6 30 26 4 [[712, 970]] 1.0 9gl9 TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL8A P00533 701 1021 1210.0 A1IMT:61105 Type1.5_Back Active DFGin 6.1092 14.3266 BLAminus -129.76, -176.54 64.1, 87.88 -100.03, 29.35 290.94, 79.71 -65.82, -30.33 in-in in 8.3521 Saltbr-in 2.8213 HRD-in -68.18, -46.36 69.12, -2.54 in-in-in SNCiii in-in ActLoopNT-in 2.8385 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.94, 136.71 APE9-dihe-in -136.26, 153.03 APE8-dihe-in -80.99, 80.94 APE8-rot-na 34.33 APE67-dihe-in -71.63, -8.89 -45.43, -47.1 APE12-dist-na 12.3561 APE11-dist-na 9.4629 APE10-dist-na 10.1009 APE9-dist-in 6.473 V948R None None XRAY 1.632 0.189 0.224 A 338.0 305.0 5 30 30 0 [[712, 970]] 1.0 9gl8 TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1IMT

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9GL8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 9GL9A P00533 696 1019 1210.0 A1IMT:61103 Type1.5_Back Active DFGin 6.134 14.3515 BLAminus -126.96, -175.87 60.02, 86.56 -97.41, 25.27 289.91, 91.21 -60.54, -33.98 in-in in 8.3689 Saltbr-in 2.9348 HRD-in -68.5, -49.91 70.75, -1.83 in-in-in SNCiii in-in ActLoopNT-in 2.8766 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -79.17, 127.77 APE9-dihe-in -129.15, 139.26 APE8-dihe-in -73.46, 89.68 APE8-rot-na 31.97 APE67-dihe-in -69.08, -6.41 -52.73, -42.79 APE12-dist-na 11.7681 APE11-dist-na 10.0478 APE10-dist-na 10.6342 APE9-dist-in 6.6861 None None None XRAY 2.147 0.198 0.213 A 330.0 313.0 6 30 26 4 [[712, 970]] 1.0 9gl9 Homo sapiens TYR_EGFR_HUMAN TYR 1.1e-87 299.7 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 9GL8A P00533 701 1021 1210.0 A1IMT:61105 Type1.5_Back Active DFGin 6.1092 14.3266 BLAminus -129.76, -176.54 64.1, 87.88 -100.03, 29.35 290.94, 79.71 -65.82, -30.33 in-in in 8.3521 Saltbr-in 2.8213 HRD-in -68.18, -46.36 69.12, -2.54 in-in-in SNCiii in-in ActLoopNT-in 2.8385 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.94, 136.71 APE9-dihe-in -136.26, 153.03 APE8-dihe-in -80.99, 80.94 APE8-rot-na 34.33 APE67-dihe-in -71.63, -8.89 -45.43, -47.1 APE12-dist-na 12.3561 APE11-dist-na 9.4629 APE10-dist-na 10.1009 APE9-dist-in 6.473 V948R None None XRAY 1.632 0.189 0.224 A 338.0 305.0 5 30 30 0 [[712, 970]] 1.0 9gl8 Homo sapiens TYR_EGFR_HUMAN TYR 1.3e-85 292.9 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: A1IMT

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name