Ligand: 9VV

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQDA P10721 566 931 976.0 9VV:61001 Type1 Active DFGin 7.2932 13.71 BLAminus -125.22, 174.02 64.35, 86.97 -99.96, 22.19 287.31, 74.14 -60.97, -31.0 in-in in 7.9588 Saltbr-in 2.7238 HRD-in -96.54, -44.33 76.17, -1.79 in-in-in SNCiii in-in ActLoopNT-in 2.924 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.65, 142.04 APE9-dihe-in -121.46, 150.09 APE8-dihe-in -85.47, 74.64 APE8-rot-na 33.1 APE67-dihe-in -71.23, -8.89 -55.95, -43.17 APE12-dist-na 14.203 APE11-dist-na 9.884 APE10-dist-na 13.3311 APE9-dist-in 7.7221 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.5 0.176 0.194 A 327.0 288.0 0 30 30 0 [[589, 926]] 1.0 8pqd TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQDB P10721 566 932 976.0 9VV:61001 Type1 Active DFGin 7.3173 13.7357 BLAminus -126.15, 174.7 62.73, 89.5 -101.98, 24.1 285.73, 74.08 -62.53, -30.1 in-in in 7.8951 Saltbr-in 2.7394 HRD-in -94.72, -44.07 75.73, -0.04 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.84, 140.68 APE9-dihe-in -121.78, 149.74 APE8-dihe-in -83.35, 71.92 APE8-rot-na 35.81 APE67-dihe-in -69.81, -8.26 -54.26, -45.11 APE12-dist-na 14.1083 APE11-dist-na 9.808 APE10-dist-na 13.0668 APE9-dist-in 7.6895 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.5 0.176 0.194 B 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8pqd TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: 9VV

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQDA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQDA P10721 566 931 976.0 9VV:61001 Type1 Active DFGin 7.2932 13.71 BLAminus -125.22, 174.02 64.35, 86.97 -99.96, 22.19 287.31, 74.14 -60.97, -31.0 in-in in 7.9588 Saltbr-in 2.7238 HRD-in -96.54, -44.33 76.17, -1.79 in-in-in SNCiii in-in ActLoopNT-in 2.924 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.65, 142.04 APE9-dihe-in -121.46, 150.09 APE8-dihe-in -85.47, 74.64 APE8-rot-na 33.1 APE67-dihe-in -71.23, -8.89 -55.95, -43.17 APE12-dist-na 14.203 APE11-dist-na 9.884 APE10-dist-na 13.3311 APE9-dist-in 7.7221 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.5 0.176 0.194 A 327.0 288.0 0 30 30 0 [[589, 926]] 1.0 8pqd Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQDB P10721 566 932 976.0 9VV:61001 Type1 Active DFGin 7.3173 13.7357 BLAminus -126.15, 174.7 62.73, 89.5 -101.98, 24.1 285.73, 74.08 -62.53, -30.1 in-in in 7.8951 Saltbr-in 2.7394 HRD-in -94.72, -44.07 75.73, -0.04 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.84, 140.68 APE9-dihe-in -121.78, 149.74 APE8-dihe-in -83.35, 71.92 APE8-rot-na 35.81 APE67-dihe-in -69.81, -8.26 -54.26, -45.11 APE12-dist-na 14.1083 APE11-dist-na 9.808 APE10-dist-na 13.0668 APE9-dist-in 7.6895 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.5 0.176 0.194 B 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8pqd Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: 9VV

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name