Ligand: 9KI

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQFC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQFA P10721 566 931 976.0 9KI:61001 Type1 Active DFGin 7.0145 14.1154 BLAminus -129.63, 178.86 58.56, 84.18 -100.12, 27.12 285.56, 70.86 -63.9, -31.9 in-in in 8.2013 Saltbr-in 2.803 HRD-in -89.02, -45.2 77.26, -1.95 in-in-in SNCiii in-in ActLoopNT-in 2.8919 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.18, 135.2 APE9-dihe-in -119.42, 150.13 APE8-dihe-in -82.55, 76.11 APE8-rot-na 32.82 APE67-dihe-in -71.08, -6.74 -56.61, -43.88 APE12-dist-na 14.1038 APE11-dist-na 9.5347 APE10-dist-na 12.7415 APE9-dist-in 7.5842 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.9 0.197 0.219 A 327.0 285.0 3 30 28 2 [[589, 926]] 1.0 8pqf TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQFC P10721 566 932 976.0 9KI:61001 Type1 Active DFGin 7.0287 13.7337 BLAminus -130.97, -177.27 58.3, 84.55 -100.6, 29.27 285.15, 69.87 -63.54, -39.98 in-in in 8.0627 Saltbr-in 2.8502 HRD-in -83.32, -44.04 70.24, 3.72 in-in-in SNCiii in-in ActLoopNT-in 2.8213 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.35, 134.14 APE9-dihe-in -127.54, 151.09 APE8-dihe-in -80.47, 79.59 APE8-rot-na 32.02 APE67-dihe-in -71.78, -11.06 -58.34, -43.23 APE12-dist-na 13.9262 APE11-dist-na 8.9923 APE10-dist-na 11.8078 APE9-dist-in 7.2304 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.9 0.197 0.219 C 327.0 287.0 2 30 28 2 [[589, 926]] 1.0 8pqf TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: 9KI

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQFC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQFA P10721 566 931 976.0 9KI:61001 Type1 Active DFGin 7.0145 14.1154 BLAminus -129.63, 178.86 58.56, 84.18 -100.12, 27.12 285.56, 70.86 -63.9, -31.9 in-in in 8.2013 Saltbr-in 2.803 HRD-in -89.02, -45.2 77.26, -1.95 in-in-in SNCiii in-in ActLoopNT-in 2.8919 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.18, 135.2 APE9-dihe-in -119.42, 150.13 APE8-dihe-in -82.55, 76.11 APE8-rot-na 32.82 APE67-dihe-in -71.08, -6.74 -56.61, -43.88 APE12-dist-na 14.1038 APE11-dist-na 9.5347 APE10-dist-na 12.7415 APE9-dist-in 7.5842 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.9 0.197 0.219 A 327.0 285.0 3 30 28 2 [[589, 926]] 1.0 8pqf Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQFC P10721 566 932 976.0 9KI:61001 Type1 Active DFGin 7.0287 13.7337 BLAminus -130.97, -177.27 58.3, 84.55 -100.6, 29.27 285.15, 69.87 -63.54, -39.98 in-in in 8.0627 Saltbr-in 2.8502 HRD-in -83.32, -44.04 70.24, 3.72 in-in-in SNCiii in-in ActLoopNT-in 2.8213 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.35, 134.14 APE9-dihe-in -127.54, 151.09 APE8-dihe-in -80.47, 79.59 APE8-rot-na 32.02 APE67-dihe-in -71.78, -11.06 -58.34, -43.23 APE12-dist-na 13.9262 APE11-dist-na 8.9923 APE10-dist-na 11.8078 APE9-dist-in 7.2304 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.9 0.197 0.219 C 327.0 287.0 2 30 28 2 [[589, 926]] 1.0 8pqf Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: 9KI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name