Ligand: 9JI

Total number of chains: 5
Active chains: 5
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 8PQ9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQGA P10721 566 931 976.0 9JI:61001 Type1 Active DFGin 7.0429 14.1671 BLAminus -124.55, -174.12 54.99, 78.46 -96.45, 26.87 280.71, 70.71 -64.48, -33.68 in-in in 8.0418 Saltbr-in 2.847 HRD-in -90.54, -41.04 71.94, -5.78 in-in-in SNCiii in-in ActLoopNT-in 3.0249 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.66, 135.23 APE9-dihe-in -115.63, 149.54 APE8-dihe-in -83.89, 83.11 APE8-rot-na 25.85 APE67-dihe-in -70.62, -11.93 -61.47, -41.45 APE12-dist-na 999.0 APE11-dist-na 9.8657 APE10-dist-na 13.0316 APE9-dist-in 7.6588 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 A 327.0 283.0 5 30 25 5 [[589, 926]] 1.0 8pqg TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQGC P10721 565 932 976.0 9JI:61001 Type1 Active DFGin 6.9981 13.7774 BLAminus -125.01, -177.18 59.69, 81.81 -99.94, 28.85 284.0, 66.15 -68.84, -20.03 in-in in 7.8376 Saltbr-in 2.8929 HRD-in -87.34, -47.72 75.4, 1.14 in-in-in SNCiii in-in ActLoopNT-in 2.9945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.89, 137.72 APE9-dihe-in -124.07, 148.98 APE8-dihe-in -81.48, 76.95 APE8-rot-na 33.1 APE67-dihe-in -72.2, -11.85 -56.44, -41.57 APE12-dist-na 14.3671 APE11-dist-na 10.0194 APE10-dist-na 12.9788 APE9-dist-in 7.6471 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 C 327.0 290.0 0 30 30 0 [[589, 926]] 1.0 8pqg TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQ9A P10721 566 931 976.0 9JI:61001 Type1 Active DFGin 7.2517 13.8147 BLAminus -126.16, 175.91 62.85, 85.59 -99.46, 22.74 287.74, 71.92 -60.52, -32.33 in-in in 8.0453 Saltbr-in 2.8915 HRD-in -88.42, -47.53 73.24, 0.77 in-in-in SNCiii in-in ActLoopNT-in 2.8934 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.84, 137.41 APE9-dihe-in -124.52, 150.02 APE8-dihe-in -81.94, 72.53 APE8-rot-na 33.61 APE67-dihe-in -70.63, -9.48 -54.32, -43.88 APE12-dist-na 14.1614 APE11-dist-na 9.6594 APE10-dist-na 12.9192 APE9-dist-in 7.6321 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.7 0.191 0.204 A 327.0 288.0 0 30 30 0 [[589, 926]] 1.0 8pq9 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQ9C P10721 565 931 976.0 9JI:61001 Type1 Active DFGin 7.2525 13.6293 BLAminus -125.82, 176.11 61.62, 87.15 -98.51, 24.61 286.73, 70.75 -59.71, -35.16 in-in in 7.7982 Saltbr-in 2.831 HRD-in -85.3, -42.79 66.08, 3.46 in-in-in SNCiii in-in ActLoopNT-in 2.8809 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.23, 137.49 APE9-dihe-in -122.07, 151.56 APE8-dihe-in -81.17, 74.2 APE8-rot-na 33.62 APE67-dihe-in -73.31, -9.55 -56.17, -42.06 APE12-dist-na 14.024 APE11-dist-na 9.7411 APE10-dist-na 12.8723 APE9-dist-in 7.6213 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.7 0.191 0.204 C 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8pq9 TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR PDGFRA PGFRA_HUMAN 8PQHA P16234 555 971 1089.0 9JI:1001 Type1 Active DFGin 7.1176 13.5042 BLAminus -137.77, -173.06 54.37, 84.67 -94.17, 27.12 292.06, 83.63 -63.26, -46.8 in-in in 7.9228 Saltbr-in 3.2447 HRD-in -71.43, -45.05 70.07, -2.59 in-in-in SNCiii in-in ActLoopNT-in 2.9791 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.37, 127.86 APE9-dihe-in -120.13, 154.51 APE8-dihe-in -81.88, 68.37 APE8-rot-na 25.31 APE67-dihe-in -67.91, -9.11 -50.35, -46.55 APE12-dist-na 6.6948 APE11-dist-na 11.7329 APE10-dist-na 11.1167 APE9-dist-in 7.073 T674I None None XRAY 2.5 0.22 0.249 A 352.0 321.0 23 30 30 0 [[593, 952]] 1.0 8pqh TYR_PDGFRA_HUMAN TYR 1.8e-106 361.4 1.0 260.0 260.0 835 836 837 839 841 627 644 648 815 817 816 818.0 877 865 860 859 858 857 856 855 854 675 Platelet-derived growth factor receptor alpha

Ligand: 9JI

Total number of chains: 5
Active chains: 5
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 8PQ9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQGA P10721 566 931 976.0 9JI:61001 Type1 Active DFGin 7.0429 14.1671 BLAminus -124.55, -174.12 54.99, 78.46 -96.45, 26.87 280.71, 70.71 -64.48, -33.68 in-in in 8.0418 Saltbr-in 2.847 HRD-in -90.54, -41.04 71.94, -5.78 in-in-in SNCiii in-in ActLoopNT-in 3.0249 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -64.66, 135.23 APE9-dihe-in -115.63, 149.54 APE8-dihe-in -83.89, 83.11 APE8-rot-na 25.85 APE67-dihe-in -70.62, -11.93 -61.47, -41.45 APE12-dist-na 999.0 APE11-dist-na 9.8657 APE10-dist-na 13.0316 APE9-dist-in 7.6588 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 A 327.0 283.0 5 30 25 5 [[589, 926]] 1.0 8pqg Homo sapiens TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQGC P10721 565 932 976.0 9JI:61001 Type1 Active DFGin 6.9981 13.7774 BLAminus -125.01, -177.18 59.69, 81.81 -99.94, 28.85 284.0, 66.15 -68.84, -20.03 in-in in 7.8376 Saltbr-in 2.8929 HRD-in -87.34, -47.72 75.4, 1.14 in-in-in SNCiii in-in ActLoopNT-in 2.9945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -62.89, 137.72 APE9-dihe-in -124.07, 148.98 APE8-dihe-in -81.48, 76.95 APE8-rot-na 33.1 APE67-dihe-in -72.2, -11.85 -56.44, -41.57 APE12-dist-na 14.3671 APE11-dist-na 10.0194 APE10-dist-na 12.9788 APE9-dist-in 7.6471 I563S,V569S,Y609Q,L631S,M651E,I662H,T670I,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 2.4 0.207 0.231 C 327.0 290.0 0 30 30 0 [[589, 926]] 1.0 8pqg Homo sapiens TYR_KIT_HUMAN TYR 4.7e-104 353.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQ9A P10721 566 931 976.0 9JI:61001 Type1 Active DFGin 7.2517 13.8147 BLAminus -126.16, 175.91 62.85, 85.59 -99.46, 22.74 287.74, 71.92 -60.52, -32.33 in-in in 8.0453 Saltbr-in 2.8915 HRD-in -88.42, -47.53 73.24, 0.77 in-in-in SNCiii in-in ActLoopNT-in 2.8934 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.84, 137.41 APE9-dihe-in -124.52, 150.02 APE8-dihe-in -81.94, 72.53 APE8-rot-na 33.61 APE67-dihe-in -70.63, -9.48 -54.32, -43.88 APE12-dist-na 14.1614 APE11-dist-na 9.6594 APE10-dist-na 12.9192 APE9-dist-in 7.6321 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.7 0.191 0.204 A 327.0 288.0 0 30 30 0 [[589, 926]] 1.0 8pq9 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQ9C P10721 565 931 976.0 9JI:61001 Type1 Active DFGin 7.2525 13.6293 BLAminus -125.82, 176.11 61.62, 87.15 -98.51, 24.61 286.73, 70.75 -59.71, -35.16 in-in in 7.7982 Saltbr-in 2.831 HRD-in -85.3, -42.79 66.08, 3.46 in-in-in SNCiii in-in ActLoopNT-in 2.8809 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.23, 137.49 APE9-dihe-in -122.07, 151.56 APE8-dihe-in -81.17, 74.2 APE8-rot-na 33.62 APE67-dihe-in -73.31, -9.55 -56.17, -42.06 APE12-dist-na 14.024 APE11-dist-na 9.7411 APE10-dist-na 12.8723 APE9-dist-in 7.6213 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.7 0.191 0.204 C 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8pq9 Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR PDGFRA PGFRA_HUMAN 8PQHA P16234 555 971 1089.0 9JI:1001 Type1 Active DFGin 7.1176 13.5042 BLAminus -137.77, -173.06 54.37, 84.67 -94.17, 27.12 292.06, 83.63 -63.26, -46.8 in-in in 7.9228 Saltbr-in 3.2447 HRD-in -71.43, -45.05 70.07, -2.59 in-in-in SNCiii in-in ActLoopNT-in 2.9791 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.37, 127.86 APE9-dihe-in -120.13, 154.51 APE8-dihe-in -81.88, 68.37 APE8-rot-na 25.31 APE67-dihe-in -67.91, -9.11 -50.35, -46.55 APE12-dist-na 6.6948 APE11-dist-na 11.7329 APE10-dist-na 11.1167 APE9-dist-in 7.073 T674I None None XRAY 2.5 0.22 0.249 A 352.0 321.0 23 30 30 0 [[593, 952]] 1.0 8pqh Homo sapiens TYR_PDGFRA_HUMAN TYR 1.8e-106 361.4 1.0 260.0 260.0 835 836 837 839 841 627 644 648 815 817 816 818.0 877 865 860 859 858 857 856 855 854 675 Platelet-derived growth factor receptor alpha

Ligand: 9JI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name