Ligand: 98A

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQAA P10721 566 930 976.0 98A:61001 Type1 Active DFGin 7.1932 13.8564 BLAminus -122.96, 175.12 63.58, 85.5 -99.75, 20.34 285.92, 74.4 -56.64, -34.52 in-in in 7.9437 Saltbr-in 2.7295 HRD-in -94.67, -43.8 74.34, -1.0 in-in-in SNCiii in-in ActLoopNT-in 2.8978 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.76, 135.8 APE9-dihe-in -118.85, 149.47 APE8-dihe-in -80.85, 69.46 APE8-rot-na 34.58 APE67-dihe-in -70.51, -9.55 -51.81, -44.71 APE12-dist-na 14.0739 APE11-dist-na 9.7489 APE10-dist-na 13.0472 APE9-dist-in 7.6397 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.65 0.189 0.214 A 327.0 287.0 0 30 30 0 [[589, 926]] 1.0 8pqa TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQAC P10721 566 932 976.0 98A:61001 Type1 Active DFGin 7.3653 13.8712 BLAminus -128.44, 177.8 60.72, 85.37 -96.93, 21.25 285.42, 76.05 -60.3, -30.33 in-in in 7.8626 Saltbr-in 2.6735 HRD-in -93.28, -41.69 73.67, -0.95 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.53, 141.87 APE9-dihe-in -121.42, 146.47 APE8-dihe-in -77.65, 70.99 APE8-rot-na 35.44 APE67-dihe-in -71.59, -10.06 -56.88, -41.82 APE12-dist-na 14.2028 APE11-dist-na 9.4882 APE10-dist-na 13.0079 APE9-dist-in 7.6331 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.65 0.189 0.214 C 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8pqa TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: 98A

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8PQAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8PQAA P10721 566 930 976.0 98A:61001 Type1 Active DFGin 7.1932 13.8564 BLAminus -122.96, 175.12 63.58, 85.5 -99.75, 20.34 285.92, 74.4 -56.64, -34.52 in-in in 7.9437 Saltbr-in 2.7295 HRD-in -94.67, -43.8 74.34, -1.0 in-in-in SNCiii in-in ActLoopNT-in 2.8978 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -71.76, 135.8 APE9-dihe-in -118.85, 149.47 APE8-dihe-in -80.85, 69.46 APE8-rot-na 34.58 APE67-dihe-in -70.51, -9.55 -51.81, -44.71 APE12-dist-na 14.0739 APE11-dist-na 9.7489 APE10-dist-na 13.0472 APE9-dist-in 7.6397 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.65 0.189 0.214 A 327.0 287.0 0 30 30 0 [[589, 926]] 1.0 8pqa Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8PQAC P10721 566 932 976.0 98A:61001 Type1 Active DFGin 7.3653 13.8712 BLAminus -128.44, 177.8 60.72, 85.37 -96.93, 21.25 285.42, 76.05 -60.3, -30.33 in-in in 7.8626 Saltbr-in 2.6735 HRD-in -93.28, -41.69 73.67, -0.95 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -63.53, 141.87 APE9-dihe-in -121.42, 146.47 APE8-dihe-in -77.65, 70.99 APE8-rot-na 35.44 APE67-dihe-in -71.59, -10.06 -56.88, -41.82 APE12-dist-na 14.2028 APE11-dist-na 9.4882 APE10-dist-na 13.0079 APE9-dist-in 7.6331 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.65 0.189 0.214 C 327.0 289.0 0 30 30 0 [[589, 926]] 1.0 8pqa Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

Ligand: 98A

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name