Ligand: 7ZX

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ETAA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ETAA P24941 1 298 298.0 7ZX:60601 Type1 Active DFGin 6.843 15.39 BLAminus -130.87, 177.54 61.19, 88.41 -108.49, 29.69 278.15, 78.57 -76.9, -23.03 in-in in 8.704 Saltbr-in 3.381 HRD-in -80.89, -60.33 80.32, 14.58 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.1, 157.98 APE9-dihe-na 80.83, 121.24 APE8-dihe-in -46.09, 138.61 APE8-rot-in 304.51 APE67-dihe-in -61.54, -19.39 -60.41, -43.93 APE12-dist-in 13.081 APE11-dist-in 11.907 APE10-dist-in 7.224 APE9-dist-in 3.18 None TPO160 TPO160 XRAY 2.512 0.22 0.24 A 302 298 0 0 0 0 [[4, 286]] 1.0 9eta CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ETAC P24941 1 296 298.0 7ZX:60301 Type1 Active DFGin 6.608 15.586 BLAminus -137.08, 177.84 55.91, 77.1 -88.51, 26.15 277.04, 73.55 -60.47, -35.41 in-in in 8.739 Saltbr-in 2.914 HRD-in -81.68, -51.59 67.1, 13.15 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.15, 148.64 APE9-dihe-na 70.71, 128.57 APE8-dihe-in -53.3, 142.24 APE8-rot-in 310.82 APE67-dihe-in -59.33, -28.84 -51.21, -47.8 APE12-dist-in 13.08 APE11-dist-in 10.731 APE10-dist-in 7.013 APE9-dist-in 3.3 None TPO160 TPO160 XRAY 2.512 0.22 0.24 C 302 296 0 0 0 0 [[4, 286]] 1.0 9eta CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 7ZX

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9ETAA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 9ETAA P24941 1 298 298.0 7ZX:60601 Type1 Active DFGin 6.843 15.39 BLAminus -130.87, 177.54 61.19, 88.41 -108.49, 29.69 278.15, 78.57 -76.9, -23.03 in-in in 8.704 Saltbr-in 3.381 HRD-in -80.89, -60.33 80.32, 14.58 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -122.1, 157.98 APE9-dihe-na 80.83, 121.24 APE8-dihe-in -46.09, 138.61 APE8-rot-in 304.51 APE67-dihe-in -61.54, -19.39 -60.41, -43.93 APE12-dist-in 13.081 APE11-dist-in 11.907 APE10-dist-in 7.224 APE9-dist-in 3.18 None TPO160 TPO160 XRAY 2.512 0.22 0.24 A 302 298 0 0 0 0 [[4, 286]] 1.0 9eta Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 9ETAC P24941 1 296 298.0 7ZX:60301 Type1 Active DFGin 6.608 15.586 BLAminus -137.08, 177.84 55.91, 77.1 -88.51, 26.15 277.04, 73.55 -60.47, -35.41 in-in in 8.739 Saltbr-in 2.914 HRD-in -81.68, -51.59 67.1, 13.15 in-in-in SNCiii in-in ActLoopNT-in 2.983 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.15, 148.64 APE9-dihe-na 70.71, 128.57 APE8-dihe-in -53.3, 142.24 APE8-rot-in 310.82 APE67-dihe-in -59.33, -28.84 -51.21, -47.8 APE12-dist-in 13.08 APE11-dist-in 10.731 APE10-dist-in 7.013 APE9-dist-in 3.3 None TPO160 TPO160 XRAY 2.512 0.22 0.24 C 302 296 0 0 0 0 [[4, 286]] 1.0 9eta Homo sapiens CMGC_CDK2_HUMAN CMGC 6.7e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 7ZX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name