Ligand: 7YG

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 4ACCA
DFGin BLBtrans 1 33.3% 4ACMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4ACMA P24941 1 298 298.0 7YG:61302 Type1 Inactive DFGin 10.7808 17.9648 BLBtrans -112.58, 148.13 72.17, 28.34 -71.04, 117.13 228.95, 112.04 92.36, -0.32 out-none out 15.0084 Saltbr-none 999.0 HRD-in -83.27, -56.83 80.89, -15.76 none-out-out SNCnoo out-out ActLoopNT-out 6.1486 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 127.54 APE9-dihe-na -64.12, 121.26 APE8-dihe-in -82.01, 126.96 APE8-rot-in 299.69 APE67-dihe-in -52.71, -31.21 -101.9, -6.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.2504 APE9-dist-out 10.8807 None None None XRAY 1.63 0.185 0.218 A 299.0 277.0 21 28 16 12 [[4, 286]] 1.0 4acm CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC GSK3B GSK3B_HUMAN 4ACCA P49841 35 385 420.0 7YG:1387 Type1 Active DFGin 7.1831 13.5808 BLAminus -136.28, 179.66 61.59, 88.25 -100.04, 20.56 281.3, 79.98 -65.9, -21.03 in-in in 8.3469 Saltbr-in 2.7616 HRD-in -66.74, -44.81 68.93, 1.06 in-in-in SNCiii in-in ActLoopNT-in 2.8975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.14, 170.6 APE9-dihe-na 77.6, 138.09 APE8-dihe-in -85.62, 145.43 APE8-rot-in 296.7 APE67-dihe-inflip 94.96, -30.16 -47.88, 136.19 APE12-dist-in 13.0341 APE11-dist-in 10.957 APE10-dist-in 5.8889 APE9-dist-in 3.171 None None None XRAY 2.21 0.191 0.219 A 465.0 351.0 0 27 27 0 [[56, 340]] 1.0 4acc CMGC_GSK3B_HUMAN CMGC 4.4e-70 242.4 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4ACCB P49841 35 385 420.0 7YG:1386 Type1 Active DFGin 7.2279 13.5244 BLAminus -136.66, 179.59 61.79, 88.29 -99.73, 21.22 281.91, 80.18 -66.08, -22.29 in-in in 8.2447 Saltbr-in 2.8714 HRD-in -66.61, -45.06 69.24, 1.05 in-in-in SNCiii in-in ActLoopNT-in 2.8922 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.27, 172.02 APE9-dihe-na 75.79, 137.96 APE8-dihe-in -86.62, 146.41 APE8-rot-in 295.61 APE67-dihe-inflip 93.46, -30.62 -49.23, 136.97 APE12-dist-in 13.056 APE11-dist-in 11.009 APE10-dist-in 5.9124 APE9-dist-in 3.1824 None None None XRAY 2.21 0.191 0.219 B 465.0 351.0 0 27 27 0 [[56, 340]] 1.0 4acc CMGC_GSK3B_HUMAN CMGC 4.4e-70 242.4 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta

Ligand: 7YG

Total number of chains: 3
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 66.7% 4ACCA
DFGin BLBtrans 1 33.3% 4ACMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 4ACMA P24941 1 298 298.0 7YG:61302 Type1 Inactive DFGin 10.7808 17.9648 BLBtrans -112.58, 148.13 72.17, 28.34 -71.04, 117.13 228.95, 112.04 92.36, -0.32 out-none out 15.0084 Saltbr-none 999.0 HRD-in -83.27, -56.83 80.89, -15.76 none-out-out SNCnoo out-out ActLoopNT-out 6.1486 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 127.54 APE9-dihe-na -64.12, 121.26 APE8-dihe-in -82.01, 126.96 APE8-rot-in 299.69 APE67-dihe-in -52.71, -31.21 -101.9, -6.18 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 19.2504 APE9-dist-out 10.8807 None None None XRAY 1.63 0.185 0.218 A 299.0 277.0 21 28 16 12 [[4, 286]] 1.0 4acm Homo sapiens CMGC_CDK2_HUMAN CMGC 6.4e-90 307.8 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC GSK3B GSK3B_HUMAN 4ACCA P49841 35 385 420.0 7YG:1387 Type1 Active DFGin 7.1831 13.5808 BLAminus -136.28, 179.66 61.59, 88.25 -100.04, 20.56 281.3, 79.98 -65.9, -21.03 in-in in 8.3469 Saltbr-in 2.7616 HRD-in -66.74, -44.81 68.93, 1.06 in-in-in SNCiii in-in ActLoopNT-in 2.8975 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.14, 170.6 APE9-dihe-na 77.6, 138.09 APE8-dihe-in -85.62, 145.43 APE8-rot-in 296.7 APE67-dihe-inflip 94.96, -30.16 -47.88, 136.19 APE12-dist-in 13.0341 APE11-dist-in 10.957 APE10-dist-in 5.8889 APE9-dist-in 3.171 None None None XRAY 2.21 0.191 0.219 A 465.0 351.0 0 27 27 0 [[56, 340]] 1.0 4acc Homo sapiens CMGC_GSK3B_HUMAN CMGC 4.4e-70 242.4 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4ACCB P49841 35 385 420.0 7YG:1386 Type1 Active DFGin 7.2279 13.5244 BLAminus -136.66, 179.59 61.79, 88.29 -99.73, 21.22 281.91, 80.18 -66.08, -22.29 in-in in 8.2447 Saltbr-in 2.8714 HRD-in -66.61, -45.06 69.24, 1.05 in-in-in SNCiii in-in ActLoopNT-in 2.8922 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -79.27, 172.02 APE9-dihe-na 75.79, 137.96 APE8-dihe-in -86.62, 146.41 APE8-rot-in 295.61 APE67-dihe-inflip 93.46, -30.62 -49.23, 136.97 APE12-dist-in 13.056 APE11-dist-in 11.009 APE10-dist-in 5.9124 APE9-dist-in 3.1824 None None None XRAY 2.21 0.191 0.219 B 465.0 351.0 0 27 27 0 [[56, 340]] 1.0 4acc Homo sapiens CMGC_GSK3B_HUMAN CMGC 4.4e-70 242.4 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta

Ligand: 7YG

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name