Ligand: 7AA

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5LXCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK2 DYRK2_HUMAN 5LXCA Q92630 153 536 601.0 7AA:60501 Type1 Inactive DFGin 7.0765 15.3959 BLAminus -127.7, 168.29 65.71, 89.28 -103.99, 15.3 281.54, 81.72 -66.81, -20.15 in-in in 8.6919 Saltbr-in 2.8935 HRD-in -69.9, -43.78 75.48, 2.4 in-in-out SNCiio in-out ActLoopNT-in 2.8987 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.55, 166.23 APE9-dihe-na 72.78, 145.6 APE8-dihe-in -76.68, 135.17 APE8-rot-out 177.09 APE67-dihe-in -59.77, -30.24 -44.95, -46.79 APE12-dist-in 13.3422 APE11-dist-in 11.7482 APE10-dist-in 7.517 APE9-dist-in 3.2859 None PTR382 PTR382 XRAY 2.15 0.208 0.254 A 408.0 384.0 0 25 25 0 [[222, 535]] 1.0 5lxc CMGC_DYRK2_HUMAN CMGC 1.2e-98 336.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN 5LXCB Q92630 153 538 601.0 7AA:60501 Type1 Inactive DFGin 7.0576 15.3507 BLAminus -125.13, 171.0 62.64, 89.27 -105.23, 19.5 281.52, 82.75 -66.91, -27.57 in-in in 8.8073 Saltbr-in 2.9781 HRD-in -70.76, -50.91 83.26, -7.25 in-in-out SNCiio in-out ActLoopNT-in 2.943 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -139.21, 164.87 APE9-dihe-na 72.46, 149.37 APE8-dihe-in -74.96, 138.82 APE8-rot-out 175.15 APE67-dihe-in -59.45, -29.64 -49.5, -49.1 APE12-dist-in 13.3485 APE11-dist-in 11.6973 APE10-dist-in 7.4606 APE9-dist-in 3.1371 None PTR382 PTR382 XRAY 2.15 0.208 0.254 B 408.0 386.0 0 25 25 0 [[222, 535]] 1.0 5lxc CMGC_DYRK2_HUMAN CMGC 1.2e-98 336.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2

Ligand: 7AA

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5LXCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK2 DYRK2_HUMAN 5LXCA Q92630 153 536 601.0 7AA:60501 Type1 Inactive DFGin 7.0765 15.3959 BLAminus -127.7, 168.29 65.71, 89.28 -103.99, 15.3 281.54, 81.72 -66.81, -20.15 in-in in 8.6919 Saltbr-in 2.8935 HRD-in -69.9, -43.78 75.48, 2.4 in-in-out SNCiio in-out ActLoopNT-in 2.8987 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -133.55, 166.23 APE9-dihe-na 72.78, 145.6 APE8-dihe-in -76.68, 135.17 APE8-rot-out 177.09 APE67-dihe-in -59.77, -30.24 -44.95, -46.79 APE12-dist-in 13.3422 APE11-dist-in 11.7482 APE10-dist-in 7.517 APE9-dist-in 3.2859 None PTR382 PTR382 XRAY 2.15 0.208 0.254 A 408.0 384.0 0 25 25 0 [[222, 535]] 1.0 5lxc Homo sapiens CMGC_DYRK2_HUMAN CMGC 1.2e-98 336.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN 5LXCB Q92630 153 538 601.0 7AA:60501 Type1 Inactive DFGin 7.0576 15.3507 BLAminus -125.13, 171.0 62.64, 89.27 -105.23, 19.5 281.52, 82.75 -66.91, -27.57 in-in in 8.8073 Saltbr-in 2.9781 HRD-in -70.76, -50.91 83.26, -7.25 in-in-out SNCiio in-out ActLoopNT-in 2.943 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -139.21, 164.87 APE9-dihe-na 72.46, 149.37 APE8-dihe-in -74.96, 138.82 APE8-rot-out 175.15 APE67-dihe-in -59.45, -29.64 -49.5, -49.1 APE12-dist-in 13.3485 APE11-dist-in 11.6973 APE10-dist-in 7.4606 APE9-dist-in 3.1371 None PTR382 PTR382 XRAY 2.15 0.208 0.254 B 408.0 386.0 0 25 25 0 [[222, 535]] 1.0 5lxc Homo sapiens CMGC_DYRK2_HUMAN CMGC 1.2e-98 336.0 1.0 301.0 301.0 367 368 369 371 373 251 266 270 345 347 346 348.0 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2

Ligand: 7AA

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name