Ligand: 6SD

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5KGKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK PIM1 PIM1_HUMAN 5KGKA P11309 33 305 313.0 6SD:407 Type1 Active DFGin 6.3082 14.8602 BLAminus -128.4, 171.34 59.1, 83.1 -92.34, 16.26 283.46, 79.02 -66.84, -16.78 in-in in 8.9281 Saltbr-in 2.7226 HRD-naA -66.62, -48.72 69.73, 2.6 in-in-in SNCiii in-in ActLoopNT-in 2.8541 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.74, 32.55 APE9-dihe-na -90.23, -157.96 APE8-dihe-in -86.86, 120.62 APE8-rot-in 311.8 APE67-dihe-in -66.57, -13.56 -54.03, -44.15 APE12-dist-in 9.7032 APE11-dist-in 8.8498 APE10-dist-in 5.6821 APE9-dist-in 3.7634 None None None XRAY 2.66 0.188 0.206 A 276.0 273.0 0 26 26 0 [[38, 290]] 1.0 5kgk CAMK_PIM1_HUMAN CAMK 2.5e-65 226.2 1.0 256.0 256.0 185 186 187 189 191 67 89 93 164 166 165 167.0 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
CMGC DYRK1A DYR1A_HUMAN 7A4ZA Q13627 148 481 763.0 6SD:60501 Type1 Active DFGin 7.3003 14.4561 BLAminus -123.85, 174.34 70.88, 81.03 -96.04, 32.37 287.17, 75.22 -72.9, -22.44 in-in in 8.5921 Saltbr-in 2.7044 HRD-in -62.51, -50.76 77.01, -4.38 in-in-in SNCiii in-in ActLoopNT-in 2.8459 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.05, 171.4 APE9-dihe-na 73.73, 155.23 APE8-dihe-in -74.89, 141.08 APE8-rot-in 296.68 APE67-dihe-in -55.98, -24.62 -56.22, -49.4 APE12-dist-in 12.8905 APE11-dist-in 11.2253 APE10-dist-in 6.8866 APE9-dist-in 3.0483 None PTR321 PTR321 XRAY 1.9 0.175 0.215 A 359.0 330.0 4 25 25 0 [[159, 479]] 1.0 7a4z CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: 6SD

Total number of chains: 2
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5KGKA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK PIM1 PIM1_HUMAN 5KGKA P11309 33 305 313.0 6SD:407 Type1 Active DFGin 6.3082 14.8602 BLAminus -128.4, 171.34 59.1, 83.1 -92.34, 16.26 283.46, 79.02 -66.84, -16.78 in-in in 8.9281 Saltbr-in 2.7226 HRD-naA -66.62, -48.72 69.73, 2.6 in-in-in SNCiii in-in ActLoopNT-in 2.8541 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.74, 32.55 APE9-dihe-na -90.23, -157.96 APE8-dihe-in -86.86, 120.62 APE8-rot-in 311.8 APE67-dihe-in -66.57, -13.56 -54.03, -44.15 APE12-dist-in 9.7032 APE11-dist-in 8.8498 APE10-dist-in 5.6821 APE9-dist-in 3.7634 None None None XRAY 2.66 0.188 0.206 A 276.0 273.0 0 26 26 0 [[38, 290]] 1.0 5kgk Homo sapiens CAMK_PIM1_HUMAN CAMK 2.5e-65 226.2 1.0 256.0 256.0 185 186 187 189 191 67 89 93 164 166 165 167.0 224 211 206 205 204 203 202 201 200 121 Serine/threonine-protein kinase pim-1
CMGC DYRK1A DYR1A_HUMAN 7A4ZA Q13627 148 481 763.0 6SD:60501 Type1 Active DFGin 7.3003 14.4561 BLAminus -123.85, 174.34 70.88, 81.03 -96.04, 32.37 287.17, 75.22 -72.9, -22.44 in-in in 8.5921 Saltbr-in 2.7044 HRD-in -62.51, -50.76 77.01, -4.38 in-in-in SNCiii in-in ActLoopNT-in 2.8459 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.05, 171.4 APE9-dihe-na 73.73, 155.23 APE8-dihe-in -74.89, 141.08 APE8-rot-in 296.68 APE67-dihe-in -55.98, -24.62 -56.22, -49.4 APE12-dist-in 12.8905 APE11-dist-in 11.2253 APE10-dist-in 6.8866 APE9-dist-in 3.0483 None PTR321 PTR321 XRAY 1.9 0.175 0.215 A 359.0 330.0 4 25 25 0 [[159, 479]] 1.0 7a4z Homo sapiens CMGC_DYRK1A_HUMAN CMGC 8.2e-91 310.2 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

Ligand: 6SD

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name