Ligand: 6FD

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1VA P49759 148 483 484.0 6FD:60501 Type1 Active DFGin 7.1 14.1716 BLAminus -126.87, 172.93 72.75, 87.91 -109.91, 21.95 296.61, 87.13 -77.69, -9.89 in-in in 8.5266 Saltbr-in 2.7359 HRD-in -74.36, -52.4 82.96, -16.81 in-in-in SNCiii in-in ActLoopNT-in 2.8778 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.9, 168.51 APE9-dihe-na 72.23, 149.39 APE8-dihe-in -71.93, 136.52 APE8-rot-in 285.15 APE67-dihe-in -66.67, -20.56 -35.82, -53.71 APE12-dist-in 13.5279 APE11-dist-in 11.4445 APE10-dist-in 7.2811 APE9-dist-in 3.0427 None None None XRAY 2.52 0.201 0.244 A 339.0 336.0 0 25 25 0 [[161, 477]] 1.0 5j1v CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VB P49759 148 482 484.0 6FD:60501 Type1 Active DFGin 7.1093 14.1198 BLAminus -126.74, 175.0 70.24, 87.64 -108.44, 20.05 295.73, 90.04 -77.7, -8.55 in-in in 8.5763 Saltbr-in 2.7543 HRD-in -73.08, -51.15 80.15, -14.17 in-in-in SNCiii in-in ActLoopNT-in 2.8769 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.41, 168.72 APE9-dihe-na 72.72, 151.05 APE8-dihe-in -70.92, 135.35 APE8-rot-in 286.36 APE67-dihe-in -65.82, -21.41 -37.05, -51.94 APE12-dist-in 13.782 APE11-dist-in 11.5423 APE10-dist-in 7.3562 APE9-dist-in 3.0498 None None None XRAY 2.52 0.201 0.244 B 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 5j1v CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VC P49759 148 483 484.0 6FD:60501 Type1 Inactive DFGin 7.0653 14.1863 BLAminus -127.76, 172.5 71.94, 87.97 -108.84, 22.87 296.53, 88.54 -79.84, -9.02 in-in in 8.5354 Saltbr-in 2.7469 HRD-in -76.64, -52.07 83.95, -17.44 in-in-out SNCiio in-out ActLoopNT-in 2.8928 ActLoopCT-out nonTYR APEdihe_aannn APEdist_oion APE10-dihe-na -156.89, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -20.42 999.0, 999.0 APE12-dist-out 14.2512 APE11-dist-in 11.6023 APE10-dist-out 9.6806 APE9-dist-none 999.0 None None None XRAY 2.52 0.201 0.244 C 339.0 312.0 24 25 22 3 [[161, 477]] 1.0 5j1v CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: 6FD

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1VA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1VA P49759 148 483 484.0 6FD:60501 Type1 Active DFGin 7.1 14.1716 BLAminus -126.87, 172.93 72.75, 87.91 -109.91, 21.95 296.61, 87.13 -77.69, -9.89 in-in in 8.5266 Saltbr-in 2.7359 HRD-in -74.36, -52.4 82.96, -16.81 in-in-in SNCiii in-in ActLoopNT-in 2.8778 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.9, 168.51 APE9-dihe-na 72.23, 149.39 APE8-dihe-in -71.93, 136.52 APE8-rot-in 285.15 APE67-dihe-in -66.67, -20.56 -35.82, -53.71 APE12-dist-in 13.5279 APE11-dist-in 11.4445 APE10-dist-in 7.2811 APE9-dist-in 3.0427 None None None XRAY 2.52 0.201 0.244 A 339.0 336.0 0 25 25 0 [[161, 477]] 1.0 5j1v Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VB P49759 148 482 484.0 6FD:60501 Type1 Active DFGin 7.1093 14.1198 BLAminus -126.74, 175.0 70.24, 87.64 -108.44, 20.05 295.73, 90.04 -77.7, -8.55 in-in in 8.5763 Saltbr-in 2.7543 HRD-in -73.08, -51.15 80.15, -14.17 in-in-in SNCiii in-in ActLoopNT-in 2.8769 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.41, 168.72 APE9-dihe-na 72.72, 151.05 APE8-dihe-in -70.92, 135.35 APE8-rot-in 286.36 APE67-dihe-in -65.82, -21.41 -37.05, -51.94 APE12-dist-in 13.782 APE11-dist-in 11.5423 APE10-dist-in 7.3562 APE9-dist-in 3.0498 None None None XRAY 2.52 0.201 0.244 B 339.0 335.0 0 25 25 0 [[161, 477]] 1.0 5j1v Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VC P49759 148 483 484.0 6FD:60501 Type1 Inactive DFGin 7.0653 14.1863 BLAminus -127.76, 172.5 71.94, 87.97 -108.84, 22.87 296.53, 88.54 -79.84, -9.02 in-in in 8.5354 Saltbr-in 2.7469 HRD-in -76.64, -52.07 83.95, -17.44 in-in-out SNCiio in-out ActLoopNT-in 2.8928 ActLoopCT-out nonTYR APEdihe_aannn APEdist_oion APE10-dihe-na -156.89, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -20.42 999.0, 999.0 APE12-dist-out 14.2512 APE11-dist-in 11.6023 APE10-dist-out 9.6806 APE9-dist-none 999.0 None None None XRAY 2.52 0.201 0.244 C 339.0 312.0 24 25 22 3 [[161, 477]] 1.0 5j1v Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1.0 301.0 301.0 324 325 326 328 330 191 206 210 285 287 286 288.0 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: 6FD

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name