Ligand: 6FD

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1VA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1VA P49759 148 483 484.0 6FD:60501 Type1 Active DFGin 7.1 14.172 BLAminus -126.87, 172.93 72.75, 87.91 -109.91, 21.95 296.61, 87.13 -77.69, -9.89 in-in in 8.527 Saltbr-in 2.736 HRD-in -74.36, -52.4 82.96, -16.81 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.9, 168.51 APE9-dihe-na 72.23, 149.39 APE8-dihe-in -71.93, 136.52 APE8-rot-in 285.15 APE67-dihe-in -66.67, -20.56 -35.82, -53.71 APE12-dist-in 13.528 APE11-dist-in 11.444 APE10-dist-in 7.281 APE9-dist-in 3.043 None None None XRAY 2.52 0.201 0.244 A 339 336 0 0 0 0 [[161, 477]] 1.0 5j1v CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VB P49759 148 482 484.0 6FD:60501 Type1 Active DFGin 7.109 14.12 BLAminus -126.74, 175.0 70.24, 87.64 -108.44, 20.05 295.73, 90.04 -77.7, -8.55 in-in in 8.576 Saltbr-in 2.754 HRD-in -73.08, -51.15 80.15, -14.17 in-in-in SNCiii in-in ActLoopNT-in 2.877 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.41, 168.72 APE9-dihe-na 72.72, 151.05 APE8-dihe-in -70.92, 135.35 APE8-rot-in 286.36 APE67-dihe-in -65.82, -21.41 -37.05, -51.94 APE12-dist-in 13.782 APE11-dist-in 11.542 APE10-dist-in 7.356 APE9-dist-in 3.05 None None None XRAY 2.52 0.201 0.244 B 339 335 0 0 0 0 [[161, 477]] 1.0 5j1v CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VC P49759 148 483 484.0 6FD:60501 Type1 Inactive DFGin 7.065 14.186 BLAminus -127.76, 172.5 71.94, 87.97 -108.84, 22.87 296.53, 88.54 -79.84, -9.02 in-in in 8.535 Saltbr-in 2.747 HRD-in -76.64, -52.07 83.95, -17.44 in-in-out SNCiio in-out ActLoopNT-in 2.893 ActLoopCT-out nonTYR APEdihe_aannn APEdist_oion APE10-dihe-na -156.89, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -20.42 999.0, 999.0 APE12-dist-out 14.251 APE11-dist-in 11.602 APE10-dist-out 9.681 APE9-dist-none 999.0 None None None XRAY 2.52 0.201 0.244 C 339 312 24 0 0 3 [[161, 477]] 1.0 5j1v CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: 6FD

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1VA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1VA P49759 148 483 484.0 6FD:60501 Type1 Active DFGin 7.1 14.172 BLAminus -126.87, 172.93 72.75, 87.91 -109.91, 21.95 296.61, 87.13 -77.69, -9.89 in-in in 8.527 Saltbr-in 2.736 HRD-in -74.36, -52.4 82.96, -16.81 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.9, 168.51 APE9-dihe-na 72.23, 149.39 APE8-dihe-in -71.93, 136.52 APE8-rot-in 285.15 APE67-dihe-in -66.67, -20.56 -35.82, -53.71 APE12-dist-in 13.528 APE11-dist-in 11.444 APE10-dist-in 7.281 APE9-dist-in 3.043 None None None XRAY 2.52 0.201 0.244 A 339 336 0 0 0 0 [[161, 477]] 1.0 5j1v Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VB P49759 148 482 484.0 6FD:60501 Type1 Active DFGin 7.109 14.12 BLAminus -126.74, 175.0 70.24, 87.64 -108.44, 20.05 295.73, 90.04 -77.7, -8.55 in-in in 8.576 Saltbr-in 2.754 HRD-in -73.08, -51.15 80.15, -14.17 in-in-in SNCiii in-in ActLoopNT-in 2.877 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.41, 168.72 APE9-dihe-na 72.72, 151.05 APE8-dihe-in -70.92, 135.35 APE8-rot-in 286.36 APE67-dihe-in -65.82, -21.41 -37.05, -51.94 APE12-dist-in 13.782 APE11-dist-in 11.542 APE10-dist-in 7.356 APE9-dist-in 3.05 None None None XRAY 2.52 0.201 0.244 B 339 335 0 0 0 0 [[161, 477]] 1.0 5j1v Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1VC P49759 148 483 484.0 6FD:60501 Type1 Inactive DFGin 7.065 14.186 BLAminus -127.76, 172.5 71.94, 87.97 -108.84, 22.87 296.53, 88.54 -79.84, -9.02 in-in in 8.535 Saltbr-in 2.747 HRD-in -76.64, -52.07 83.95, -17.44 in-in-out SNCiio in-out ActLoopNT-in 2.893 ActLoopCT-out nonTYR APEdihe_aannn APEdist_oion APE10-dihe-na -156.89, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -20.42 999.0, 999.0 APE12-dist-out 14.251 APE11-dist-in 11.602 APE10-dist-out 9.681 APE9-dist-none 999.0 None None None XRAY 2.52 0.201 0.244 C 339 312 24 0 0 3 [[161, 477]] 1.0 5j1v Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

Ligand: 6FD

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name