Ligand: 55S

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5CYIA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 5CYIA P24941 1 298 298.0 55S:60301 Type1 Active DFGin 6.767 14.97 BLAminus -137.64, 176.63 47.15, 80.48 -91.39, 21.66 281.55, 70.58 -67.03, -18.55 in-in in 8.62 Saltbr-in 2.688 HRD-in -78.06, -52.75 68.08, 20.4 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.3, 140.21 APE9-dihe-na 78.36, 138.66 APE8-dihe-in -62.96, 141.91 APE8-rot-in 296.28 APE67-dihe-in -57.57, -24.32 -47.6, -52.43 APE12-dist-in 13.034 APE11-dist-in 10.317 APE10-dist-in 7.494 APE9-dist-in 3.236 None TPO160 TPO160 XRAY 2.0 0.228 0.255 A 303 298 0 0 0 0 [[4, 286]] 1.0 5cyi CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5CYIC P24941 1 296 298.0 55S:60301 Type1 Active DFGin 6.739 14.921 BLAminus -137.77, 174.67 47.68, 81.07 -90.89, 22.34 281.65, 70.16 -66.05, -19.77 in-in in 8.583 Saltbr-in 2.693 HRD-in -76.15, -53.07 68.94, 20.52 in-in-in SNCiii in-in ActLoopNT-in 2.9 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.13, 139.64 APE9-dihe-na 76.95, 137.97 APE8-dihe-in -61.9, 140.82 APE8-rot-in 297.24 APE67-dihe-in -53.17, -25.9 -44.59, -55.44 APE12-dist-in 12.993 APE11-dist-in 10.338 APE10-dist-in 7.436 APE9-dist-in 3.216 None TPO160 TPO160 XRAY 2.0 0.228 0.255 C 303 296 0 0 0 0 [[4, 286]] 1.0 5cyi CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 55S

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5CYIA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 5CYIA P24941 1 298 298.0 55S:60301 Type1 Active DFGin 6.767 14.97 BLAminus -137.64, 176.63 47.15, 80.48 -91.39, 21.66 281.55, 70.58 -67.03, -18.55 in-in in 8.62 Saltbr-in 2.688 HRD-in -78.06, -52.75 68.08, 20.4 in-in-in SNCiii in-in ActLoopNT-in 2.878 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -145.3, 140.21 APE9-dihe-na 78.36, 138.66 APE8-dihe-in -62.96, 141.91 APE8-rot-in 296.28 APE67-dihe-in -57.57, -24.32 -47.6, -52.43 APE12-dist-in 13.034 APE11-dist-in 10.317 APE10-dist-in 7.494 APE9-dist-in 3.236 None TPO160 TPO160 XRAY 2.0 0.228 0.255 A 303 298 0 0 0 0 [[4, 286]] 1.0 5cyi Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 5CYIC P24941 1 296 298.0 55S:60301 Type1 Active DFGin 6.739 14.921 BLAminus -137.77, 174.67 47.68, 81.07 -90.89, 22.34 281.65, 70.16 -66.05, -19.77 in-in in 8.583 Saltbr-in 2.693 HRD-in -76.15, -53.07 68.94, 20.52 in-in-in SNCiii in-in ActLoopNT-in 2.9 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -147.13, 139.64 APE9-dihe-na 76.95, 137.97 APE8-dihe-in -61.9, 140.82 APE8-rot-in 297.24 APE67-dihe-in -53.17, -25.9 -44.59, -55.44 APE12-dist-in 12.993 APE11-dist-in 10.338 APE10-dist-in 7.436 APE9-dist-in 3.216 None TPO160 TPO160 XRAY 2.0 0.228 0.255 C 303 296 0 0 0 0 [[4, 286]] 1.0 5cyi Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 55S

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name