Ligand: 529

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2BPMA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2BPMA P24941 1 298 298.0 529:61299 Type1 Inactive DFGin 6.239 15.11 BLAminus -142.26, 176.11 58.91, 81.01 -97.86, 30.66 284.19, 66.4 -66.03, -17.23 in-in in 8.702 Saltbr-in 3.207 HRD-in -74.89, -55.37 69.86, 9.24 in-in-out SNCiio in-out ActLoopNT-in 2.876 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -145.78, 149.41 APE9-dihe-na -60.82, 153.33 APE8-dihe-in -56.05, 145.85 APE8-rot-out 190.64 APE67-dihe-in -49.62, -26.99 -36.83, -56.93 APE12-dist-in 10.954 APE11-dist-out 6.128 APE10-dist-out 9.188 APE9-dist-in 3.97 None None None XRAY 2.4 0.229 0.271 A 309 298 0 0 0 0 [[4, 286]] 1.0 2bpm CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2BPMC P24941 1 298 298.0 529:61299 Type1 Active DFGin 6.476 15.691 BLAminus -139.11, -176.99 50.31, 82.01 -98.98, 24.72 279.58, 68.95 -62.44, -20.88 in-in in 8.975 Saltbr-in 3.405 HRD-in -80.64, -57.02 72.88, 2.66 in-in-in SNCiii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.51, -77.27 APE9-dihe-na -63.86, 135.95 APE8-dihe-in -52.79, 132.77 APE8-rot-in 309.35 APE67-dihe-in -57.16, -24.3 -34.82, -55.34 APE12-dist-in 13.242 APE11-dist-in 11.949 APE10-dist-in 7.171 APE9-dist-in 3.521 None None None XRAY 2.4 0.229 0.271 C 309 298 0 0 0 0 [[4, 286]] 1.0 2bpm CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 529

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2BPMA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2BPMA P24941 1 298 298.0 529:61299 Type1 Inactive DFGin 6.239 15.11 BLAminus -142.26, 176.11 58.91, 81.01 -97.86, 30.66 284.19, 66.4 -66.03, -17.23 in-in in 8.702 Saltbr-in 3.207 HRD-in -74.89, -55.37 69.86, 9.24 in-in-out SNCiio in-out ActLoopNT-in 2.876 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -145.78, 149.41 APE9-dihe-na -60.82, 153.33 APE8-dihe-in -56.05, 145.85 APE8-rot-out 190.64 APE67-dihe-in -49.62, -26.99 -36.83, -56.93 APE12-dist-in 10.954 APE11-dist-out 6.128 APE10-dist-out 9.188 APE9-dist-in 3.97 None None None XRAY 2.4 0.229 0.271 A 309 298 0 0 0 0 [[4, 286]] 1.0 2bpm Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2BPMC P24941 1 298 298.0 529:61299 Type1 Active DFGin 6.476 15.691 BLAminus -139.11, -176.99 50.31, 82.01 -98.98, 24.72 279.58, 68.95 -62.44, -20.88 in-in in 8.975 Saltbr-in 3.405 HRD-in -80.64, -57.02 72.88, 2.66 in-in-in SNCiii in-in ActLoopNT-in 2.882 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.51, -77.27 APE9-dihe-na -63.86, 135.95 APE8-dihe-in -52.79, 132.77 APE8-rot-in 309.35 APE67-dihe-in -57.16, -24.3 -34.82, -55.34 APE12-dist-in 13.242 APE11-dist-in 11.949 APE10-dist-in 7.171 APE9-dist-in 3.521 None None None XRAY 2.4 0.229 0.271 C 309 298 0 0 0 0 [[4, 286]] 1.0 2bpm Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 529

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name