Ligand: 514

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2C4GA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2C4GA P24941 1 297 298.0 514:60306 Type1 Inactive DFGin 6.374 15.686 BLAminus -138.0, -179.21 56.78, 81.52 -100.19, 24.26 280.76, 69.34 -56.0, -30.57 in-in in 9.074 Saltbr-in 3.53 HRD-in -75.28, -49.4 66.04, 8.2 in-in-out SNCiio in-out ActLoopNT-in 2.765 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -135.18, 160.53 APE9-dihe-na -59.36, 149.34 APE8-dihe-in -58.64, 140.5 APE8-rot-out 179.78 APE67-dihe-in -54.42, -23.62 -30.84, -55.83 APE12-dist-in 10.723 APE11-dist-out 5.978 APE10-dist-out 9.285 APE9-dist-in 3.726 None None None XRAY 2.7 0.233 0.25 A 309 297 0 0 0 0 [[4, 286]] 1.0 2c4g CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C4GC P24941 1 298 298.0 514:60306 Type1 Active DFGin 6.367 15.719 BLAminus -139.83, -179.8 56.9, 82.39 -100.75, 22.8 279.84, 72.16 -55.14, -30.61 in-in in 9.107 Saltbr-in 3.525 HRD-in -76.45, -47.57 65.3, 7.78 in-in-in SNCiii in-in ActLoopNT-in 2.765 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.95, -47.05 APE9-dihe-na -79.06, 130.37 APE8-dihe-in -53.02, 141.81 APE8-rot-in 298.24 APE67-dihe-in -53.93, -25.26 -49.41, -57.46 APE12-dist-in 13.735 APE11-dist-in 11.863 APE10-dist-in 6.729 APE9-dist-in 3.743 None None None XRAY 2.7 0.233 0.25 C 309 298 0 0 0 0 [[4, 286]] 1.0 2c4g CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 514

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2C4GA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 2C4GA P24941 1 297 298.0 514:60306 Type1 Inactive DFGin 6.374 15.686 BLAminus -138.0, -179.21 56.78, 81.52 -100.19, 24.26 280.76, 69.34 -56.0, -30.57 in-in in 9.074 Saltbr-in 3.53 HRD-in -75.28, -49.4 66.04, 8.2 in-in-out SNCiio in-out ActLoopNT-in 2.765 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -135.18, 160.53 APE9-dihe-na -59.36, 149.34 APE8-dihe-in -58.64, 140.5 APE8-rot-out 179.78 APE67-dihe-in -54.42, -23.62 -30.84, -55.83 APE12-dist-in 10.723 APE11-dist-out 5.978 APE10-dist-out 9.285 APE9-dist-in 3.726 None None None XRAY 2.7 0.233 0.25 A 309 297 0 0 0 0 [[4, 286]] 1.0 2c4g Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 2C4GC P24941 1 298 298.0 514:60306 Type1 Active DFGin 6.367 15.719 BLAminus -139.83, -179.8 56.9, 82.39 -100.75, 22.8 279.84, 72.16 -55.14, -30.61 in-in in 9.107 Saltbr-in 3.525 HRD-in -76.45, -47.57 65.3, 7.78 in-in-in SNCiii in-in ActLoopNT-in 2.765 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.95, -47.05 APE9-dihe-na -79.06, 130.37 APE8-dihe-in -53.02, 141.81 APE8-rot-in 298.24 APE67-dihe-in -53.93, -25.26 -49.41, -57.46 APE12-dist-in 13.735 APE11-dist-in 11.863 APE10-dist-in 6.729 APE9-dist-in 3.743 None None None XRAY 2.7 0.233 0.25 C 309 298 0 0 0 0 [[4, 286]] 1.0 2c4g Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 514

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name