Ligand: 4B0

Total number of chains: 5
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 6HMQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 3RPSA P68400 2 335 391.0 4B0:336 Type1 Inactive DFGin 7.6817 16.266 BLAminus -111.18, 178.67 55.31, 84.42 -100.34, 15.64 295.89, 84.93 -72.06, -12.01 in-out in 9.904 Saltbr-out 5.0477 HRD-in -72.34, -48.54 70.52, 6.94 out-in-in SNCoii in-in ActLoopNT-in 3.0392 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.18, 157.82 APE9-dihe-na 77.07, -169.07 APE8-dihe-in -120.96, 142.89 APE8-rot-in 321.64 APE67-dihe-in -65.97, -19.63 -32.15, -57.51 APE12-dist-in 12.7163 APE11-dist-in 9.896 APE10-dist-in 6.0392 APE9-dist-in 3.258 None None None XRAY 2.3 0.172 0.228 A 335.0 334.0 0 27 27 0 [[39, 324]] 1.0 3rps CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 9R5CA P19784 7 333 350.0 A1JCZ:401,4B0:402 Allosteric,Type1 Active DFGin 7.3519 15.8792 BLAminus -111.92, 178.27 56.34, 80.71 -93.81, 15.08 294.28, 82.0 -67.7, -19.18 in-in in 9.0751 Saltbr-in 2.7561 HRD-in -75.1, -50.02 71.31, 12.54 in-in-in SNCiii in-in ActLoopNT-in 2.8543 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.89, 171.36 APE9-dihe-na 64.09, 173.29 APE8-dihe-in -103.87, 145.44 APE8-rot-in 299.19 APE67-dihe-in -66.53, -19.64 -38.47, -55.07 APE12-dist-in 12.6129 APE11-dist-in 10.2122 APE10-dist-in 6.1563 APE9-dist-in 3.0648 C336S None None XRAY 1.04 0.145 0.164 A 364.0 327.0 0 27 27 0 [[40, 325]] 1.0 9r5c CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.4639 16.0032 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.1932 Saltbr-in 2.8189 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.8646 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.6326 APE11-dist-in 10.194 APE10-dist-in 6.1965 APE9-dist-in 3.1721 None None None XRAY 1.05 0.129 0.15 A 364.0 328.0 0 27 27 0 [[40, 325]] 1.0 7at9 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 3OFMA P19784 8 332 350.0 4B0:351 Type1 Active DFGin 7.4521 16.2139 BLAminus -111.73, -178.5 48.98, 84.52 -96.71, 22.14 295.85, 79.54 -71.26, -18.63 in-in in 9.3086 Saltbr-in 2.7842 HRD-in -77.02, -48.96 71.36, 6.93 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 168.15 APE9-dihe-na 65.56, 166.69 APE8-dihe-in -96.6, 149.91 APE8-rot-in 302.53 APE67-dihe-in -71.5, -16.65 -41.01, -49.45 APE12-dist-in 12.7917 APE11-dist-in 10.4447 APE10-dist-in 6.3433 APE9-dist-in 3.1139 C336S None None XRAY 2.0 0.174 0.207 A 350.0 325.0 0 27 27 0 [[40, 325]] 1.0 3ofm CMGC_CSNK2A2_HUMAN CMGC 9e-70 241.1 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 6HMQA P19784 7 333 350.0 4B0:415 Type1 Inactive DFGin 7.5165 15.8973 BLAminus -111.51, 179.46 53.94, 78.75 -91.06, 16.94 297.02, 81.67 -70.65, -17.57 in-in in 9.2865 Saltbr-in 2.7 HRD-in -71.74, -48.86 71.13, 9.58 in-in-out SNCiio in-out ActLoopNT-in 2.8649 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.74, 167.44 APE9-dihe-na 67.55, 158.31 APE8-dihe-in -74.76, 147.19 APE8-rot-out 151.59 APE67-dihe-in -69.87, -15.26 -38.65, -53.1 APE12-dist-in 12.7193 APE11-dist-in 10.3723 APE10-dist-in 6.2757 APE9-dist-in 3.2165 C336S None None XRAY 0.97 0.12 0.132 A 364.0 327.0 0 27 27 0 [[40, 325]] 1.0 6hmq CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: 4B0

Total number of chains: 5
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 6HMQA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 3RPSA P68400 2 335 391.0 4B0:336 Type1 Inactive DFGin 7.6817 16.266 BLAminus -111.18, 178.67 55.31, 84.42 -100.34, 15.64 295.89, 84.93 -72.06, -12.01 in-out in 9.904 Saltbr-out 5.0477 HRD-in -72.34, -48.54 70.52, 6.94 out-in-in SNCoii in-in ActLoopNT-in 3.0392 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.18, 157.82 APE9-dihe-na 77.07, -169.07 APE8-dihe-in -120.96, 142.89 APE8-rot-in 321.64 APE67-dihe-in -65.97, -19.63 -32.15, -57.51 APE12-dist-in 12.7163 APE11-dist-in 9.896 APE10-dist-in 6.0392 APE9-dist-in 3.258 None None None XRAY 2.3 0.172 0.228 A 335.0 334.0 0 27 27 0 [[39, 324]] 1.0 3rps Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1.0 301.0 301.0 174 175 176 178 180 68 81 85 153 155 154 156.0 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 9R5CA P19784 7 333 350.0 A1JCZ:401,4B0:402 Allosteric,Type1 Active DFGin 7.3519 15.8792 BLAminus -111.92, 178.27 56.34, 80.71 -93.81, 15.08 294.28, 82.0 -67.7, -19.18 in-in in 9.0751 Saltbr-in 2.7561 HRD-in -75.1, -50.02 71.31, 12.54 in-in-in SNCiii in-in ActLoopNT-in 2.8543 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.89, 171.36 APE9-dihe-na 64.09, 173.29 APE8-dihe-in -103.87, 145.44 APE8-rot-in 299.19 APE67-dihe-in -66.53, -19.64 -38.47, -55.07 APE12-dist-in 12.6129 APE11-dist-in 10.2122 APE10-dist-in 6.1563 APE9-dist-in 3.0648 C336S None None XRAY 1.04 0.145 0.164 A 364.0 327.0 0 27 27 0 [[40, 325]] 1.0 9r5c Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.4639 16.0032 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.1932 Saltbr-in 2.8189 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.8646 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.6326 APE11-dist-in 10.194 APE10-dist-in 6.1965 APE9-dist-in 3.1721 None None None XRAY 1.05 0.129 0.15 A 364.0 328.0 0 27 27 0 [[40, 325]] 1.0 7at9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 3OFMA P19784 8 332 350.0 4B0:351 Type1 Active DFGin 7.4521 16.2139 BLAminus -111.73, -178.5 48.98, 84.52 -96.71, 22.14 295.85, 79.54 -71.26, -18.63 in-in in 9.3086 Saltbr-in 2.7842 HRD-in -77.02, -48.96 71.36, 6.93 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 168.15 APE9-dihe-na 65.56, 166.69 APE8-dihe-in -96.6, 149.91 APE8-rot-in 302.53 APE67-dihe-in -71.5, -16.65 -41.01, -49.45 APE12-dist-in 12.7917 APE11-dist-in 10.4447 APE10-dist-in 6.3433 APE9-dist-in 3.1139 C336S None None XRAY 2.0 0.174 0.207 A 350.0 325.0 0 27 27 0 [[40, 325]] 1.0 3ofm Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 9e-70 241.1 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 6HMQA P19784 7 333 350.0 4B0:415 Type1 Inactive DFGin 7.5165 15.8973 BLAminus -111.51, 179.46 53.94, 78.75 -91.06, 16.94 297.02, 81.67 -70.65, -17.57 in-in in 9.2865 Saltbr-in 2.7 HRD-in -71.74, -48.86 71.13, 9.58 in-in-out SNCiio in-out ActLoopNT-in 2.8649 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.74, 167.44 APE9-dihe-na 67.55, 158.31 APE8-dihe-in -74.76, 147.19 APE8-rot-out 151.59 APE67-dihe-in -69.87, -15.26 -38.65, -53.1 APE12-dist-in 12.7193 APE11-dist-in 10.3723 APE10-dist-in 6.2757 APE9-dist-in 3.2165 C336S None None XRAY 0.97 0.12 0.132 A 364.0 327.0 0 27 27 0 [[40, 325]] 1.0 6hmq Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1.0 301.0 301.0 175 176 177 179 181 69 82 86 154 156 155 157.0 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: 4B0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name