Ligand: 4B0

Total number of chains: 5
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 6HMQA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 3RPSA P68400 2 335 391.0 4B0:336 Type1 Inactive DFGin 7.682 16.266 BLAminus -111.18, 178.67 55.31, 84.42 -100.34, 15.64 295.89, 84.93 -72.06, -12.01 in-out in 9.904 Saltbr-out 5.048 HRD-in -72.34, -48.54 70.52, 6.94 out-in-in SNCoii in-in ActLoopNT-in 3.039 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.18, 157.82 APE9-dihe-na 77.07, -169.07 APE8-dihe-in -120.96, 142.89 APE8-rot-in 321.64 APE67-dihe-in -65.97, -19.63 -32.15, -57.51 APE12-dist-in 12.716 APE11-dist-in 9.896 APE10-dist-in 6.039 APE9-dist-in 3.258 None None None XRAY 2.3 0.172 0.228 A 335 334 0 0 0 0 [[39, 324]] 1.0 3rps CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 9R5CA P19784 7 333 350.0 A1JCZ:401,4B0:402 Allosteric,Type1 Active DFGin 7.352 15.879 BLAminus -111.92, 178.27 56.34, 80.71 -93.81, 15.08 294.28, 82.0 -67.7, -19.18 in-in in 9.075 Saltbr-in 2.756 HRD-in -75.1, -50.02 71.31, 12.54 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.89, 171.36 APE9-dihe-na 64.09, 173.29 APE8-dihe-in -103.87, 145.44 APE8-rot-in 299.19 APE67-dihe-in -66.53, -19.64 -38.47, -55.07 APE12-dist-in 12.613 APE11-dist-in 10.212 APE10-dist-in 6.156 APE9-dist-in 3.065 C336S None None XRAY 1.04 0.145 0.164 A 364 327 0 0 0 0 [[40, 325]] 1.0 9r5c CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.464 16.003 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.193 Saltbr-in 2.819 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.633 APE11-dist-in 10.194 APE10-dist-in 6.197 APE9-dist-in 3.172 None None None XRAY 1.05 0.129 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 7at9 CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 3OFMA P19784 8 332 350.0 4B0:351 Type1 Active DFGin 7.452 16.214 BLAminus -111.73, -178.5 48.98, 84.52 -96.71, 22.14 295.85, 79.54 -71.26, -18.63 in-in in 9.309 Saltbr-in 2.784 HRD-in -77.02, -48.96 71.36, 6.93 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 168.15 APE9-dihe-na 65.56, 166.69 APE8-dihe-in -96.6, 149.91 APE8-rot-in 302.53 APE67-dihe-in -71.5, -16.65 -41.01, -49.45 APE12-dist-in 12.792 APE11-dist-in 10.445 APE10-dist-in 6.343 APE9-dist-in 3.114 C336S None None XRAY 2.0 0.174 0.207 A 350 325 0 0 0 0 [[40, 325]] 1.0 3ofm CMGC_CSNK2A2_HUMAN CMGC 9e-70 241.1 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 6HMQA P19784 7 333 350.0 4B0:415 Type1 Inactive DFGin 7.516 15.897 BLAminus -111.51, 179.46 53.94, 78.75 -91.06, 16.94 297.02, 81.67 -70.65, -17.57 in-in in 9.287 Saltbr-in 2.7 HRD-in -71.74, -48.86 71.13, 9.58 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.74, 167.44 APE9-dihe-na 67.55, 158.31 APE8-dihe-in -74.76, 147.19 APE8-rot-out 151.59 APE67-dihe-in -69.87, -15.26 -38.65, -53.1 APE12-dist-in 12.719 APE11-dist-in 10.372 APE10-dist-in 6.276 APE9-dist-in 3.216 C336S None None XRAY 0.97 0.12 0.132 A 364 327 0 0 0 0 [[40, 325]] 1.0 6hmq CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: 4B0

Total number of chains: 5
Active chains: 2
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 6HMQA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CSNK2A1 CSK21_HUMAN 3RPSA P68400 2 335 391.0 4B0:336 Type1 Inactive DFGin 7.682 16.266 BLAminus -111.18, 178.67 55.31, 84.42 -100.34, 15.64 295.89, 84.93 -72.06, -12.01 in-out in 9.904 Saltbr-out 5.048 HRD-in -72.34, -48.54 70.52, 6.94 out-in-in SNCoii in-in ActLoopNT-in 3.039 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.18, 157.82 APE9-dihe-na 77.07, -169.07 APE8-dihe-in -120.96, 142.89 APE8-rot-in 321.64 APE67-dihe-in -65.97, -19.63 -32.15, -57.51 APE12-dist-in 12.716 APE11-dist-in 9.896 APE10-dist-in 6.039 APE9-dist-in 3.258 None None None XRAY 2.3 0.172 0.228 A 335 334 0 0 0 0 [[39, 324]] 1.0 3rps Homo sapiens CMGC_CSNK2A1_HUMAN CMGC 1.3e-69 240.6 1 301 301 174 175 176 178 180 68 81 85 153 155 154 156 214 201 196 195 194 193 192 191 190 114 Casein kinase II subunit alpha
CMGC CSNK2A2 CSK22_HUMAN 9R5CA P19784 7 333 350.0 A1JCZ:401,4B0:402 Allosteric,Type1 Active DFGin 7.352 15.879 BLAminus -111.92, 178.27 56.34, 80.71 -93.81, 15.08 294.28, 82.0 -67.7, -19.18 in-in in 9.075 Saltbr-in 2.756 HRD-in -75.1, -50.02 71.31, 12.54 in-in-in SNCiii in-in ActLoopNT-in 2.854 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -137.89, 171.36 APE9-dihe-na 64.09, 173.29 APE8-dihe-in -103.87, 145.44 APE8-rot-in 299.19 APE67-dihe-in -66.53, -19.64 -38.47, -55.07 APE12-dist-in 12.613 APE11-dist-in 10.212 APE10-dist-in 6.156 APE9-dist-in 3.065 C336S None None XRAY 1.04 0.145 0.164 A 364 327 0 0 0 0 [[40, 325]] 1.0 9r5c Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 7AT9A P19784 6 333 350.0 42J:501,4B0:511,42J:512 Allosteric,Type1,Allosteric Inactive DFGin 7.464 16.003 BLAminus -113.43, 178.2 56.27, 78.92 -92.2, 17.57 296.55, 81.41 -69.68, -18.53 in-in in 9.193 Saltbr-in 2.819 HRD-in -73.6, -48.99 71.34, 11.57 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.69, 170.0 APE9-dihe-na 63.51, 159.84 APE8-dihe-in -73.34, 145.57 APE8-rot-out 161.02 APE67-dihe-in -67.92, -15.68 -40.13, -55.96 APE12-dist-in 12.633 APE11-dist-in 10.194 APE10-dist-in 6.197 APE9-dist-in 3.172 None None None XRAY 1.05 0.129 0.15 A 364 328 0 0 0 0 [[40, 325]] 1.0 7at9 Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 3OFMA P19784 8 332 350.0 4B0:351 Type1 Active DFGin 7.452 16.214 BLAminus -111.73, -178.5 48.98, 84.52 -96.71, 22.14 295.85, 79.54 -71.26, -18.63 in-in in 9.309 Saltbr-in 2.784 HRD-in -77.02, -48.96 71.36, 6.93 in-in-in SNCiii in-in ActLoopNT-in 2.917 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.3, 168.15 APE9-dihe-na 65.56, 166.69 APE8-dihe-in -96.6, 149.91 APE8-rot-in 302.53 APE67-dihe-in -71.5, -16.65 -41.01, -49.45 APE12-dist-in 12.792 APE11-dist-in 10.445 APE10-dist-in 6.343 APE9-dist-in 3.114 C336S None None XRAY 2.0 0.174 0.207 A 350 325 0 0 0 0 [[40, 325]] 1.0 3ofm Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 9e-70 241.1 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'
CMGC CSNK2A2 CSK22_HUMAN 6HMQA P19784 7 333 350.0 4B0:415 Type1 Inactive DFGin 7.516 15.897 BLAminus -111.51, 179.46 53.94, 78.75 -91.06, 16.94 297.02, 81.67 -70.65, -17.57 in-in in 9.287 Saltbr-in 2.7 HRD-in -71.74, -48.86 71.13, 9.58 in-in-out SNCiio in-out ActLoopNT-in 2.865 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.74, 167.44 APE9-dihe-na 67.55, 158.31 APE8-dihe-in -74.76, 147.19 APE8-rot-out 151.59 APE67-dihe-in -69.87, -15.26 -38.65, -53.1 APE12-dist-in 12.719 APE11-dist-in 10.372 APE10-dist-in 6.276 APE9-dist-in 3.216 C336S None None XRAY 0.97 0.12 0.132 A 364 327 0 0 0 0 [[40, 325]] 1.0 6hmq Homo sapiens CMGC_CSNK2A2_HUMAN CMGC 1e-69 241.0 1 301 301 175 176 177 179 181 69 82 86 154 156 155 157 215 202 197 196 195 194 193 192 191 115 Casein kinase II subunit alpha'

Ligand: 4B0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name