Ligand: 2WE

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4PTCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC GSK3B GSK3B_HUMAN 4PTCA P49841 36 381 420.0 2WE:501 Type1 Active DFGin 6.9363 14.3975 BLAminus -147.73, -174.11 62.98, 81.81 -100.26, 25.83 284.28, 79.03 -59.65, -43.28 in-in in 9.1619 Saltbr-in 2.729 HRD-in -73.84, -45.42 69.86, 9.93 in-in-in SNCiii in-in ActLoopNT-in 2.77 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -85.04, 172.51 APE9-dihe-na 77.59, 144.28 APE8-dihe-in -89.54, 156.63 APE8-rot-in 297.82 APE67-dihe-inflip 95.7, -27.15 -58.15, 143.88 APE12-dist-in 13.0497 APE11-dist-in 10.7791 APE10-dist-in 6.0041 APE9-dist-in 3.2718 None None None XRAY 2.711 0.217 0.281 A 441.0 342.0 4 27 27 0 [[56, 340]] 1.0 4ptc CMGC_GSK3B_HUMAN CMGC 3.7e-70 242.6 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4PTCB P49841 35 385 420.0 2WE:501 Type1 Active DFGin 7.2125 14.6055 BLAminus -123.82, -167.89 50.38, 80.91 -94.33, 28.59 284.85, 71.64 -64.12, -29.45 in-in in 8.9235 Saltbr-in 2.4023 HRD-in -67.43, -42.31 63.02, 14.07 in-in-in SNCiii in-in ActLoopNT-in 2.9358 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -78.89, 173.71 APE9-dihe-na 81.21, 152.66 APE8-dihe-in -112.25, 156.82 APE8-rot-in 292.56 APE67-dihe-inflip 100.85, -22.79 -44.26, 123.15 APE12-dist-in 13.0829 APE11-dist-in 10.9184 APE10-dist-in 5.8898 APE9-dist-in 3.2799 None None None XRAY 2.711 0.217 0.281 B 441.0 347.0 4 27 27 0 [[56, 340]] 1.0 4ptc CMGC_GSK3B_HUMAN CMGC 3.7e-70 242.6 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta

Ligand: 2WE

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4PTCA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC GSK3B GSK3B_HUMAN 4PTCA P49841 36 381 420.0 2WE:501 Type1 Active DFGin 6.9363 14.3975 BLAminus -147.73, -174.11 62.98, 81.81 -100.26, 25.83 284.28, 79.03 -59.65, -43.28 in-in in 9.1619 Saltbr-in 2.729 HRD-in -73.84, -45.42 69.86, 9.93 in-in-in SNCiii in-in ActLoopNT-in 2.77 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -85.04, 172.51 APE9-dihe-na 77.59, 144.28 APE8-dihe-in -89.54, 156.63 APE8-rot-in 297.82 APE67-dihe-inflip 95.7, -27.15 -58.15, 143.88 APE12-dist-in 13.0497 APE11-dist-in 10.7791 APE10-dist-in 6.0041 APE9-dist-in 3.2718 None None None XRAY 2.711 0.217 0.281 A 441.0 342.0 4 27 27 0 [[56, 340]] 1.0 4ptc Homo sapiens CMGC_GSK3B_HUMAN CMGC 3.7e-70 242.6 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta
CMGC GSK3B GSK3B_HUMAN 4PTCB P49841 35 385 420.0 2WE:501 Type1 Active DFGin 7.2125 14.6055 BLAminus -123.82, -167.89 50.38, 80.91 -94.33, 28.59 284.85, 71.64 -64.12, -29.45 in-in in 8.9235 Saltbr-in 2.4023 HRD-in -67.43, -42.31 63.02, 14.07 in-in-in SNCiii in-in ActLoopNT-in 2.9358 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -78.89, 173.71 APE9-dihe-na 81.21, 152.66 APE8-dihe-in -112.25, 156.82 APE8-rot-in 292.56 APE67-dihe-inflip 100.85, -22.79 -44.26, 123.15 APE12-dist-in 13.0829 APE11-dist-in 10.9184 APE10-dist-in 5.8898 APE9-dist-in 3.2799 None None None XRAY 2.711 0.217 0.281 B 441.0 347.0 4 27 27 0 [[56, 340]] 1.0 4ptc Homo sapiens CMGC_GSK3B_HUMAN CMGC 3.7e-70 242.6 1.0 301.0 301.0 199 200 201 203 205 85 97 101 178 180 179 181.0 239 226 221 220 219 218 217 216 215 133 Glycogen synthase kinase-3 beta

Ligand: 2WE

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name