Ligand: 2AN

Total number of chains: 6
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 5 83.3% 3PXZA
DFGin BLAminus 1 16.7% 5AUTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DAPK1 DAPK1_HUMAN 5AUTA P53355 2 277 1430.0 2AN:301 Type1 Inactive DFGin 6.7325 14.5115 BLAminus -114.87, -178.74 65.36, 82.8 -97.46, 26.0 284.97, 73.32 -68.08, -18.37 in-in in 9.272 Saltbr-in 2.7267 HRD-in -79.24, -46.55 71.42, 2.57 in-in-out SNCiio in-out ActLoopNT-in 2.904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -108.3, 115.32 APE9-dihe-na -103.48, -132.74 APE8-dihe-in -88.72, 121.51 APE8-rot-in 303.74 APE67-dihe-in -57.21, -25.59 -46.9, -42.51 APE12-dist-in 11.124 APE11-dist-out 6.228 APE10-dist-out 9.3325 APE9-dist-in 4.9148 None None None XRAY 1.7 0.172 0.202 A 293.0 274.0 2 27 27 0 [[13, 275]] 1.0 5aut CAMK_DAPK1_HUMAN CAMK 6.1e-95 323.3 1.0 256.0 256.0 160 161 162 164 166 42 64 68 136 138 137 139.0 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 1
CMGC CDK2 CDK2_HUMAN 3PXFA P24941 1 298 298.0 2AN:60304,2AN:60305 Allosteric,Type3 Inactive DFGin 6.8039 14.9525 BLBminus -156.99, 169.67 57.7, 49.35 -58.76, 147.9 286.72, 73.73 -84.97, 33.17 out-out out 17.1179 Saltbr-out 15.9633 HRD-in -83.12, -53.61 79.99, -16.11 out-out-out SNCooo out-out ActLoopNT-out 10.2801 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -144.89, 166.86 APE9-dihe-na -179.55, 11.71 APE8-dihe-out -60.35, -25.0 APE8-rot-in 308.45 APE67-dihe-in -57.16, -27.46 -60.95, -33.0 APE12-dist-out 17.9953 APE11-dist-out 18.6251 APE10-dist-out 15.5668 APE9-dist-out 11.4025 None None None XRAY 1.8 0.198 0.229 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 3pxf CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXZA P24941 1 298 298.0 2AN:60299,2AN:60300,JWS:60301 Allosteric,Type3,Type1 Inactive DFGin 6.8368 15.033 BLBminus -155.67, 166.51 60.28, 50.57 -60.22, 145.8 284.9, 75.18 -84.49, 38.36 out-out out 17.125 Saltbr-out 15.7892 HRD-in -85.51, -53.14 79.88, -15.95 out-out-out SNCooo out-out ActLoopNT-out 10.4931 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -158.71, 154.36 APE9-dihe-na -170.99, 21.17 APE8-dihe-out -68.66, -23.41 APE8-rot-in 291.0 APE67-dihe-in -58.73, -27.74 -57.67, -32.22 APE12-dist-out 18.6086 APE11-dist-out 18.6644 APE10-dist-out 15.3898 APE9-dist-out 11.2012 None None None XRAY 1.7 0.214 0.256 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 3pxz CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXQA P24941 1 298 298.0 2AN:60300,2AN:60301,2AN:60302 Type1,Allosteric,Type3 Inactive DFGin 6.7911 14.9577 BLBminus -156.11, 172.24 56.44, 48.4 -58.19, 145.75 280.77, 74.71 -81.02, -171.95 out-out out 17.021 Saltbr-out 15.6002 HRD-in -85.93, -53.84 79.73, -15.83 out-out-out SNCooo out-out ActLoopNT-out 10.1399 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -155.6, 50.43 APE9-dihe-na -145.4, -64.21 APE8-dihe-out -61.58, -25.66 APE8-rot-out 171.8 APE67-dihe-in -58.56, -25.05 -69.11, -27.97 APE12-dist-out 16.567 APE11-dist-out 17.7611 APE10-dist-out 20.3885 APE9-dist-out 11.3112 None None None XRAY 1.9 0.196 0.235 A 306.0 294.0 4 28 28 0 [[4, 286]] 1.0 3pxq CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PY1A P24941 1 298 298.0 SU9:60300,2AN:60301,2AN:60302 Type1,Allosteric,Type3 Inactive DFGin 6.9694 14.582 BLBminus -156.43, 165.09 55.84, 55.34 -63.31, 145.25 285.83, 75.03 -95.3, 141.59 out-out out 15.677 Saltbr-out 11.464 HRD-in -77.3, -51.37 78.87, -23.11 out-out-out SNCooo out-out ActLoopNT-out 9.4081 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -116.77, -56.62 APE9-dihe-na -53.47, -37.91 APE8-dihe-out -53.54, -42.42 APE8-rot-in 292.43 APE67-dihe-in -55.86, -28.72 -53.35, -38.93 APE12-dist-in 11.8886 APE11-dist-out 15.7468 APE10-dist-out 18.4833 APE9-dist-out 10.6737 None None None XRAY 2.05 0.199 0.251 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 3py1 CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EZ7A P24941 1 298 298.0 STU:60301,2AN:60302,2AN:60303 Type1,Type3,Allosteric Inactive DFGin 6.9781 14.6249 BLBminus -145.53, 170.39 52.9, 57.73 -61.57, 149.9 287.28, 68.06 -86.96, 168.33 out-out out 16.748 Saltbr-out 14.4128 HRD-in -86.07, -42.21 71.45, -15.9 out-out-out SNCooo out-out ActLoopNT-out 10.2365 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -63.47, 156.15 APE9-dihe-na -125.23, 14.23 APE8-dihe-out -63.17, -28.79 APE8-rot-in 293.42 APE67-dihe-in -53.71, -31.99 -57.23, -35.61 APE12-dist-out 18.4717 APE11-dist-out 18.425 APE10-dist-out 13.9772 APE9-dist-out 11.3055 None None None XRAY 2.49 0.22 0.274 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 4ez7 CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 2AN

Total number of chains: 6
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 5 83.3% 3PXZA
DFGin BLAminus 1 16.7% 5AUTA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK DAPK1 DAPK1_HUMAN 5AUTA P53355 2 277 1430.0 2AN:301 Type1 Inactive DFGin 6.7325 14.5115 BLAminus -114.87, -178.74 65.36, 82.8 -97.46, 26.0 284.97, 73.32 -68.08, -18.37 in-in in 9.272 Saltbr-in 2.7267 HRD-in -79.24, -46.55 71.42, 2.57 in-in-out SNCiio in-out ActLoopNT-in 2.904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -108.3, 115.32 APE9-dihe-na -103.48, -132.74 APE8-dihe-in -88.72, 121.51 APE8-rot-in 303.74 APE67-dihe-in -57.21, -25.59 -46.9, -42.51 APE12-dist-in 11.124 APE11-dist-out 6.228 APE10-dist-out 9.3325 APE9-dist-in 4.9148 None None None XRAY 1.7 0.172 0.202 A 293.0 274.0 2 27 27 0 [[13, 275]] 1.0 5aut Homo sapiens CAMK_DAPK1_HUMAN CAMK 6.1e-95 323.3 1.0 256.0 256.0 160 161 162 164 166 42 64 68 136 138 137 139.0 199 187 182 181 180 179 178 177 176 94 Death-associated protein kinase 1
CMGC CDK2 CDK2_HUMAN 3PXFA P24941 1 298 298.0 2AN:60304,2AN:60305 Allosteric,Type3 Inactive DFGin 6.8039 14.9525 BLBminus -156.99, 169.67 57.7, 49.35 -58.76, 147.9 286.72, 73.73 -84.97, 33.17 out-out out 17.1179 Saltbr-out 15.9633 HRD-in -83.12, -53.61 79.99, -16.11 out-out-out SNCooo out-out ActLoopNT-out 10.2801 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -144.89, 166.86 APE9-dihe-na -179.55, 11.71 APE8-dihe-out -60.35, -25.0 APE8-rot-in 308.45 APE67-dihe-in -57.16, -27.46 -60.95, -33.0 APE12-dist-out 17.9953 APE11-dist-out 18.6251 APE10-dist-out 15.5668 APE9-dist-out 11.4025 None None None XRAY 1.8 0.198 0.229 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 3pxf Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXZA P24941 1 298 298.0 2AN:60299,2AN:60300,JWS:60301 Allosteric,Type3,Type1 Inactive DFGin 6.8368 15.033 BLBminus -155.67, 166.51 60.28, 50.57 -60.22, 145.8 284.9, 75.18 -84.49, 38.36 out-out out 17.125 Saltbr-out 15.7892 HRD-in -85.51, -53.14 79.88, -15.95 out-out-out SNCooo out-out ActLoopNT-out 10.4931 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -158.71, 154.36 APE9-dihe-na -170.99, 21.17 APE8-dihe-out -68.66, -23.41 APE8-rot-in 291.0 APE67-dihe-in -58.73, -27.74 -57.67, -32.22 APE12-dist-out 18.6086 APE11-dist-out 18.6644 APE10-dist-out 15.3898 APE9-dist-out 11.2012 None None None XRAY 1.7 0.214 0.256 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 3pxz Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PXQA P24941 1 298 298.0 2AN:60300,2AN:60301,2AN:60302 Type1,Allosteric,Type3 Inactive DFGin 6.7911 14.9577 BLBminus -156.11, 172.24 56.44, 48.4 -58.19, 145.75 280.77, 74.71 -81.02, -171.95 out-out out 17.021 Saltbr-out 15.6002 HRD-in -85.93, -53.84 79.73, -15.83 out-out-out SNCooo out-out ActLoopNT-out 10.1399 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_oooo APE10-dihe-na -155.6, 50.43 APE9-dihe-na -145.4, -64.21 APE8-dihe-out -61.58, -25.66 APE8-rot-out 171.8 APE67-dihe-in -58.56, -25.05 -69.11, -27.97 APE12-dist-out 16.567 APE11-dist-out 17.7611 APE10-dist-out 20.3885 APE9-dist-out 11.3112 None None None XRAY 1.9 0.196 0.235 A 306.0 294.0 4 28 28 0 [[4, 286]] 1.0 3pxq Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 3PY1A P24941 1 298 298.0 SU9:60300,2AN:60301,2AN:60302 Type1,Allosteric,Type3 Inactive DFGin 6.9694 14.582 BLBminus -156.43, 165.09 55.84, 55.34 -63.31, 145.25 285.83, 75.03 -95.3, 141.59 out-out out 15.677 Saltbr-out 11.464 HRD-in -77.3, -51.37 78.87, -23.11 out-out-out SNCooo out-out ActLoopNT-out 9.4081 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -116.77, -56.62 APE9-dihe-na -53.47, -37.91 APE8-dihe-out -53.54, -42.42 APE8-rot-in 292.43 APE67-dihe-in -55.86, -28.72 -53.35, -38.93 APE12-dist-in 11.8886 APE11-dist-out 15.7468 APE10-dist-out 18.4833 APE9-dist-out 10.6737 None None None XRAY 2.05 0.199 0.251 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 3py1 Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 4EZ7A P24941 1 298 298.0 STU:60301,2AN:60302,2AN:60303 Type1,Type3,Allosteric Inactive DFGin 6.9781 14.6249 BLBminus -145.53, 170.39 52.9, 57.73 -61.57, 149.9 287.28, 68.06 -86.96, 168.33 out-out out 16.748 Saltbr-out 14.4128 HRD-in -86.07, -42.21 71.45, -15.9 out-out-out SNCooo out-out ActLoopNT-out 10.2365 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -63.47, 156.15 APE9-dihe-na -125.23, 14.23 APE8-dihe-out -63.17, -28.79 APE8-rot-in 293.42 APE67-dihe-in -53.71, -31.99 -57.23, -35.61 APE12-dist-out 18.4717 APE11-dist-out 18.425 APE10-dist-out 13.9772 APE9-dist-out 11.3055 None None None XRAY 2.49 0.22 0.274 A 306.0 298.0 0 28 28 0 [[4, 286]] 1.0 4ez7 Homo sapiens CMGC_CDK2_HUMAN CMGC 7e-90 307.7 1.0 301.0 301.0 144 145 146 148 150 33 51 55 124 126 125 127.0 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 2AN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name