Ligand: 2A6

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1H1QA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1H1QA P24941 1 296 298.0 2A6:61298 Type1 Inactive DFGin 6.512 14.862 BLAminus -132.06, 176.21 56.25, 86.82 -91.89, 16.14 280.93, 75.89 -52.78, -45.0 in-out in 8.598 Saltbr-out 4.199 HRD-in -78.2, -44.47 62.96, 33.71 out-in-in SNCoii in-in ActLoopNT-in 2.962 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.52, 142.46 APE9-dihe-na 75.73, 142.33 APE8-dihe-in -61.63, 140.37 APE8-rot-in 280.51 APE67-dihe-in -59.24, -24.16 -43.09, -55.2 APE12-dist-in 13.017 APE11-dist-in 10.083 APE10-dist-in 7.927 APE9-dist-in 3.398 None TPO160 TPO160 XRAY 2.5 0.238 0.332 A 303 296 0 0 0 0 [[4, 286]] 1.0 1h1q CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1H1QC P24941 1 296 298.0 2A6:61298 Type1 Active DFGin 6.238 14.7 BLAminus -137.56, 168.0 63.76, 81.0 -88.76, 14.52 280.77, 71.51 -57.63, -25.21 in-in in 8.403 Saltbr-in 2.986 HRD-in -87.0, -45.2 67.54, 31.89 in-in-in SNCiii in-in ActLoopNT-in 2.778 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.07, 157.24 APE9-dihe-na 53.6, 133.67 APE8-dihe-in -53.3, 139.53 APE8-rot-in 282.96 APE67-dihe-in -62.62, -13.03 -52.36, -46.94 APE12-dist-in 12.909 APE11-dist-in 10.223 APE10-dist-in 7.579 APE9-dist-in 3.209 None TPO160 TPO160 XRAY 2.5 0.238 0.332 C 303 296 0 0 0 0 [[4, 286]] 1.0 1h1q CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 2A6

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1H1QA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1H1QA P24941 1 296 298.0 2A6:61298 Type1 Inactive DFGin 6.512 14.862 BLAminus -132.06, 176.21 56.25, 86.82 -91.89, 16.14 280.93, 75.89 -52.78, -45.0 in-out in 8.598 Saltbr-out 4.199 HRD-in -78.2, -44.47 62.96, 33.71 out-in-in SNCoii in-in ActLoopNT-in 2.962 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.52, 142.46 APE9-dihe-na 75.73, 142.33 APE8-dihe-in -61.63, 140.37 APE8-rot-in 280.51 APE67-dihe-in -59.24, -24.16 -43.09, -55.2 APE12-dist-in 13.017 APE11-dist-in 10.083 APE10-dist-in 7.927 APE9-dist-in 3.398 None TPO160 TPO160 XRAY 2.5 0.238 0.332 A 303 296 0 0 0 0 [[4, 286]] 1.0 1h1q Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1H1QC P24941 1 296 298.0 2A6:61298 Type1 Active DFGin 6.238 14.7 BLAminus -137.56, 168.0 63.76, 81.0 -88.76, 14.52 280.77, 71.51 -57.63, -25.21 in-in in 8.403 Saltbr-in 2.986 HRD-in -87.0, -45.2 67.54, 31.89 in-in-in SNCiii in-in ActLoopNT-in 2.778 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -156.07, 157.24 APE9-dihe-na 53.6, 133.67 APE8-dihe-in -53.3, 139.53 APE8-rot-in 282.96 APE67-dihe-in -62.62, -13.03 -52.36, -46.94 APE12-dist-in 12.909 APE11-dist-in 10.223 APE10-dist-in 7.579 APE9-dist-in 3.209 None TPO160 TPO160 XRAY 2.5 0.238 0.332 C 303 296 0 0 0 0 [[4, 286]] 1.0 1h1q Homo sapiens CMGC_CDK2_HUMAN CMGC 6.8e-90 307.8 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 2A6

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name