Ligand: 292

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1VYWA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1VYWA P24941 1 298 298.0 292:62300 Type1 Inactive DFGin 6.31 15.448 BLAminus -142.09, -179.46 62.07, 68.01 -93.04, 26.77 283.3, 67.04 -60.71, -37.42 in-in in 8.774 Saltbr-in 2.688 HRD-in -75.98, -56.94 73.1, 1.68 in-in-out SNCiio in-out ActLoopNT-in 2.799 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -141.65, 150.84 APE9-dihe-na -49.59, 152.46 APE8-dihe-in -61.68, 143.78 APE8-rot-out 189.06 APE67-dihe-in -52.32, -27.96 -37.01, -54.78 APE12-dist-in 10.865 APE11-dist-out 6.148 APE10-dist-out 9.397 APE9-dist-in 3.864 None None None XRAY 2.3 0.229 0.258 A 309 298 0 0 0 0 [[4, 286]] 1.0 1vyw CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1VYWC P24941 1 298 298.0 292:62300 Type1 Active DFGin 6.523 15.767 BLAminus -146.25, 178.96 56.14, 83.81 -105.77, 25.65 281.9, 67.54 -64.15, -29.51 in-in in 8.953 Saltbr-in 3.212 HRD-in -73.63, -51.91 70.52, -1.97 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.65, -86.84 APE9-dihe-na -54.67, 131.52 APE8-dihe-in -46.41, 133.51 APE8-rot-in 308.89 APE67-dihe-in -56.19, -27.67 -42.04, -52.59 APE12-dist-in 13.579 APE11-dist-in 12.392 APE10-dist-in 7.698 APE9-dist-in 3.701 None None None XRAY 2.3 0.229 0.258 C 309 298 0 0 0 0 [[4, 286]] 1.0 1vyw CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 292

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 1VYWA
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK2 CDK2_HUMAN 1VYWA P24941 1 298 298.0 292:62300 Type1 Inactive DFGin 6.31 15.448 BLAminus -142.09, -179.46 62.07, 68.01 -93.04, 26.77 283.3, 67.04 -60.71, -37.42 in-in in 8.774 Saltbr-in 2.688 HRD-in -75.98, -56.94 73.1, 1.68 in-in-out SNCiio in-out ActLoopNT-in 2.799 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iooi APE10-dihe-na -141.65, 150.84 APE9-dihe-na -49.59, 152.46 APE8-dihe-in -61.68, 143.78 APE8-rot-out 189.06 APE67-dihe-in -52.32, -27.96 -37.01, -54.78 APE12-dist-in 10.865 APE11-dist-out 6.148 APE10-dist-out 9.397 APE9-dist-in 3.864 None None None XRAY 2.3 0.229 0.258 A 309 298 0 0 0 0 [[4, 286]] 1.0 1vyw Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2
CMGC CDK2 CDK2_HUMAN 1VYWC P24941 1 298 298.0 292:62300 Type1 Active DFGin 6.523 15.767 BLAminus -146.25, 178.96 56.14, 83.81 -105.77, 25.65 281.9, 67.54 -64.15, -29.51 in-in in 8.953 Saltbr-in 3.212 HRD-in -73.63, -51.91 70.52, -1.97 in-in-in SNCiii in-in ActLoopNT-in 2.892 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.65, -86.84 APE9-dihe-na -54.67, 131.52 APE8-dihe-in -46.41, 133.51 APE8-rot-in 308.89 APE67-dihe-in -56.19, -27.67 -42.04, -52.59 APE12-dist-in 13.579 APE11-dist-in 12.392 APE10-dist-in 7.698 APE9-dist-in 3.701 None None None XRAY 2.3 0.229 0.258 C 309 298 0 0 0 0 [[4, 286]] 1.0 1vyw Homo sapiens CMGC_CDK2_HUMAN CMGC 7.3e-90 307.6 1 301 301 144 145 146 148 150 33 51 55 124 126 125 127 185 172 167 166 165 164 163 162 161 81 Cyclin-dependent kinase 2

Ligand: 292

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name