Ligand: 1NX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ZEPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 3ZEPA P52333 814 1098 1124.0 1NX:2099 Type1 Inactive DFGin 6.4201 14.3445 BLAminus -139.2, 179.6 58.57, 83.63 -103.43, 28.82 290.46, 79.48 -67.26, -39.4 in-in in 8.1983 Saltbr-in 2.7236 HRD-in -72.97, -44.84 72.81, -0.01 in-in-out SNCiio in-out ActLoopNT-in 2.7642 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -90.83, 0.53 APE9-dihe-in -141.71, 168.37 APE8-dihe-in -61.5, 133.7 APE8-rot-na 333.46 APE67-dihe-in -72.33, -1.68 -64.6, -21.71 APE12-dist-na 13.4306 APE11-dist-na 10.6555 APE10-dist-na 6.8245 APE9-dist-in 6.4001 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 A 288.0 276.0 9 31 31 0 [[521, 779], [822, 1097]] 2.0 3zep TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPB P52333 814 1100 1124.0 1NX:2101 Type1 None DFGin 6.3528 14.2219 BLAminus -142.2, 177.46 62.39, 84.45 -101.38, 32.38 292.96, 77.07 -73.1, -37.75 in-in in 8.2407 Saltbr-in 2.735 HRD-in -71.3, -45.86 73.98, -5.89 in-in-none SNCiin in-none ActLoopNT-in 2.7688 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 174.81 APE8-dihe-in -59.17, 141.04 APE8-rot-na 332.8 APE67-dihe-in -80.76, -5.98 -67.68, -15.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.4769 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 B 288.0 270.0 17 31 27 4 [[521, 779], [822, 1097]] 2.0 3zep TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPC P52333 814 1100 1124.0 1NX:2101 Type1 None DFGin 6.2667 14.2845 BLAminus -143.3, 179.56 63.59, 86.35 -106.32, 31.56 290.45, 75.82 -68.82, -32.0 in-in in 8.1744 Saltbr-in 2.7545 HRD-in -76.43, -48.0 76.34, -21.16 in-in-none SNCiin in-none ActLoopNT-in 2.7144 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 45.01 APE9-dihe-in -93.38, 161.79 APE8-dihe-in -56.5, 116.98 APE8-rot-na 326.42 APE67-dihe-in -74.98, -4.7 -72.25, -13.12 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.7287 APE9-dist-in 6.8497 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 C 288.0 278.0 9 31 29 2 [[521, 779], [822, 1097]] 2.0 3zep TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPD P52333 814 1099 1124.0 1NX:2100 Type1 None DFGin 6.5755 14.572 BLAminus -134.12, 176.57 59.25, 80.73 -100.38, 28.57 291.24, 76.13 -63.83, -42.01 in-in in 8.3615 Saltbr-in 2.6719 HRD-in -72.39, -47.07 79.2, -13.88 in-in-none SNCiin in-none ActLoopNT-in 2.7779 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 161.47 APE8-dihe-in -52.69, 138.76 APE8-rot-na 329.47 APE67-dihe-in -77.9, -7.22 -77.25, -13.54 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.5559 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 D 288.0 274.0 12 31 28 3 [[521, 779], [822, 1097]] 2.0 3zep TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

Ligand: 1NX

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ZEPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK3-2 JAK3_HUMAN 3ZEPA P52333 814 1098 1124.0 1NX:2099 Type1 Inactive DFGin 6.4201 14.3445 BLAminus -139.2, 179.6 58.57, 83.63 -103.43, 28.82 290.46, 79.48 -67.26, -39.4 in-in in 8.1983 Saltbr-in 2.7236 HRD-in -72.97, -44.84 72.81, -0.01 in-in-out SNCiio in-out ActLoopNT-in 2.7642 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -90.83, 0.53 APE9-dihe-in -141.71, 168.37 APE8-dihe-in -61.5, 133.7 APE8-rot-na 333.46 APE67-dihe-in -72.33, -1.68 -64.6, -21.71 APE12-dist-na 13.4306 APE11-dist-na 10.6555 APE10-dist-na 6.8245 APE9-dist-in 6.4001 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 A 288.0 276.0 9 31 31 0 [[521, 779], [822, 1097]] 2.0 3zep Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPB P52333 814 1100 1124.0 1NX:2101 Type1 None DFGin 6.3528 14.2219 BLAminus -142.2, 177.46 62.39, 84.45 -101.38, 32.38 292.96, 77.07 -73.1, -37.75 in-in in 8.2407 Saltbr-in 2.735 HRD-in -71.3, -45.86 73.98, -5.89 in-in-none SNCiin in-none ActLoopNT-in 2.7688 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 174.81 APE8-dihe-in -59.17, 141.04 APE8-rot-na 332.8 APE67-dihe-in -80.76, -5.98 -67.68, -15.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.4769 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 B 288.0 270.0 17 31 27 4 [[521, 779], [822, 1097]] 2.0 3zep Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPC P52333 814 1100 1124.0 1NX:2101 Type1 None DFGin 6.2667 14.2845 BLAminus -143.3, 179.56 63.59, 86.35 -106.32, 31.56 290.45, 75.82 -68.82, -32.0 in-in in 8.1744 Saltbr-in 2.7545 HRD-in -76.43, -48.0 76.34, -21.16 in-in-none SNCiin in-none ActLoopNT-in 2.7144 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 45.01 APE9-dihe-in -93.38, 161.79 APE8-dihe-in -56.5, 116.98 APE8-rot-na 326.42 APE67-dihe-in -74.98, -4.7 -72.25, -13.12 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 10.7287 APE9-dist-in 6.8497 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 C 288.0 278.0 9 31 29 2 [[521, 779], [822, 1097]] 2.0 3zep Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZEPD P52333 814 1099 1124.0 1NX:2100 Type1 None DFGin 6.5755 14.572 BLAminus -134.12, 176.57 59.25, 80.73 -100.38, 28.57 291.24, 76.13 -63.83, -42.01 in-in in 8.3615 Saltbr-in 2.6719 HRD-in -72.39, -47.07 79.2, -13.88 in-in-none SNCiin in-none ActLoopNT-in 2.7779 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 161.47 APE8-dihe-in -52.69, 138.76 APE8-rot-na 329.47 APE67-dihe-in -77.9, -7.22 -77.25, -13.54 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.5559 C1040S,C1048S PTR980,PTR981 PTR980,PTR981 XRAY 2.35 0.226 0.265 D 288.0 274.0 12 31 28 3 [[521, 779], [822, 1097]] 2.0 3zep Homo sapiens TYR_JAK3-2_HUMAN TYR 2e-81 279.1 1.0 260.0 260.0 966 967 968 970 972 855 871 875 946 948 947 949.0 1009 997 992 991 990 989 988 987 986 903 Tyrosine-protein kinase JAK3

Ligand: 1NX

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name