Ligand: 1C8

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 1 100.0% 4I6HA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK PLK2 PLK2_HUMAN 4I6HA 1.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioo APEdist_iiio 1C8 Type1 71 - 355 0 None C83S,V87T,A119S,A216S,C259A,C291S,L335T Serine/threonine-protein kinase PLK2

Ligand: 1C8

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 1 100.0% 4I6HA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK PLK2 PLK2_HUMAN 4I6HA 1.91 Inactive DFGin‑BLBminus in-in in-out nonTYR APEdihe_aaioo APEdist_iiio 1C8 Type1 71 - 355 0 None C83S,V87T,A119S,A216S,C259A,C291S,L335T Serine/threonine-protein kinase PLK2 Homo sapiens

Ligand: 1C8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism