TYR_TXK (Tyrosine-protein kinase TXK)

Total number of chains: 2
Active chains: 2
Uniprot: TXK_HUMAN
Kinase Domain Residues: 271 - 522
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P42681-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TXK AF-P42681-K1A P42681 263 527 527.0 No_ligand No_ligand Active DFGin 6.6328 13.6787 BLAminus -132.44, -171.55 51.55, 69.06 -83.0, 15.4 301.59, 95.27 -57.86, -35.58 in-in in 8.5764 Saltbr-in 2.6615 HRD-in -75.08, -41.68 67.65, -18.65 in-in-in SNCiii in-in ActLoopNT-in 2.9812 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.29, 146.05 APE9-dihe-in -144.84, 156.38 APE8-dihe-in -77.24, 85.22 APE8-rot-na 33.39 APE67-dihe-in -69.52, -14.58 -42.3, -41.46 APE12-dist-na 14.9008 APE11-dist-na 10.0895 APE10-dist-na 11.661 APE9-dist-in 6.7244 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 29 29 0 [[271, 522]] 1.0 AF-P42681-K1 TYR_TXK_HUMAN TYR 1.6e-93 318.7 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 344 Tyrosine-protein kinase TXK
TXK AF-P42681-K3A P42681 263 527 527.0 No_ligand No_ligand Active DFGin 6.0484 14.215 BLAminus -135.98, -173.64 62.2, 60.5 -80.15, 8.22 300.29, 96.84 -61.74, -30.75 in-in in 9.381 Saltbr-in 2.9713 HRD-in -77.66, -43.08 68.55, -12.03 in-in-in SNCiii in-in ActLoopNT-in 2.9209 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.32, 142.31 APE9-dihe-in -151.52, 159.46 APE8-dihe-in -80.17, 79.38 APE8-rot-na 36.89 APE67-dihe-in -66.52, -16.96 -43.28, -45.15 APE12-dist-na 14.4501 APE11-dist-na 9.6554 APE10-dist-na 10.435 APE9-dist-in 5.792 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 29 29 0 [[271, 522]] 1.0 AF-P42681-K3 TYR_TXK_HUMAN TYR 1.6e-93 318.7 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 344 Tyrosine-protein kinase TXK

TYR_TXK (Tyrosine-protein kinase TXK)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P42681-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TXK TXK_HUMAN AF-P42681-K1A P42681 263 527 527.0 No_ligand No_ligand Active DFGin 6.6328 13.6787 BLAminus -132.44, -171.55 51.55, 69.06 -83.0, 15.4 301.59, 95.27 -57.86, -35.58 in-in in 8.5764 Saltbr-in 2.6615 HRD-in -75.08, -41.68 67.65, -18.65 in-in-in SNCiii in-in ActLoopNT-in 2.9812 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.29, 146.05 APE9-dihe-in -144.84, 156.38 APE8-dihe-in -77.24, 85.22 APE8-rot-na 33.39 APE67-dihe-in -69.52, -14.58 -42.3, -41.46 APE12-dist-na 14.9008 APE11-dist-na 10.0895 APE10-dist-na 11.661 APE9-dist-in 6.7244 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 29 29 0 [[271, 522]] 1.0 AF-P42681-K1 Homo sapiens TYR_TXK_HUMAN TYR 1.6e-93 318.7 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 344 Tyrosine-protein kinase TXK
TXK TXK_HUMAN AF-P42681-K3A P42681 263 527 527.0 No_ligand No_ligand Active DFGin 6.0484 14.215 BLAminus -135.98, -173.64 62.2, 60.5 -80.15, 8.22 300.29, 96.84 -61.74, -30.75 in-in in 9.381 Saltbr-in 2.9713 HRD-in -77.66, -43.08 68.55, -12.03 in-in-in SNCiii in-in ActLoopNT-in 2.9209 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.32, 142.31 APE9-dihe-in -151.52, 159.46 APE8-dihe-in -80.17, 79.38 APE8-rot-na 36.89 APE67-dihe-in -66.52, -16.96 -43.28, -45.15 APE12-dist-na 14.4501 APE11-dist-na 9.6554 APE10-dist-na 10.435 APE9-dist-in 5.792 None None None AF2 -1.0 1.0 1.0 A 265.0 265.0 0 29 29 0 [[271, 522]] 1.0 AF-P42681-K3 Homo sapiens TYR_TXK_HUMAN TYR 1.6e-93 318.7 1.0 260.0 260.0 407 408 409 411 413 299 314 318 387 389 388 390.0 448 436 431 430 429 428 427 426 425 344 Tyrosine-protein kinase TXK

TYR_TXK (Tyrosine-protein kinase TXK)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name