TYR_TIE1 (Tyrosine-protein kinase receptor Tie-1)

Total number of chains: 2
Active chains: 2
Uniprot: TIE1_HUMAN
Kinase Domain Residues: 839 - 1109
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P35590-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TIE1 AF-P35590-K1A P35590 831 1117 1138.0 No_ligand No_ligand Active DFGin 6.8307 14.0023 BLAminus -136.74, -177.38 58.93, 68.24 -85.88, 10.76 291.29, 88.28 -58.64, -30.14 in-in in 7.7489 Saltbr-in 2.6365 HRD-in -73.5, -44.78 67.89, -18.39 in-in-in SNCiii in-in ActLoopNT-in 2.9322 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.21, 101.49 APE9-dihe-in -132.86, 147.09 APE8-dihe-in -81.49, 82.73 APE8-rot-na 37.04 APE67-dihe-in -67.41, -15.52 -42.34, -43.57 APE12-dist-na 13.9227 APE11-dist-na 10.648 APE10-dist-na 9.259 APE9-dist-in 6.2986 None None None AF2 -1.0 1.0 1.0 A 287.0 287.0 0 27 27 0 [[839, 1109]] 1.0 AF-P35590-K1 TYR_TIE1_HUMAN TYR 5.6e-91 310.4 1.0 259.0 259.0 996 997 998 1000 1002 870 887 891 976 978 977 979.0 1035 1023 1018 1017 1016 1015 1014 1013 1012 918 Tyrosine-protein kinase receptor Tie-1
TIE1 AF-P35590-K3A P35590 831 1117 1138.0 No_ligand No_ligand Active DFGin 6.5448 13.7855 BLAminus -139.89, -178.12 57.57, 74.65 -85.7, 11.49 292.39, 98.86 -59.99, -28.25 in-in in 7.7462 Saltbr-in 2.6682 HRD-in -75.65, -45.19 65.98, -11.15 in-in-in SNCiii in-in ActLoopNT-in 2.8828 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.64, 142.79 APE9-dihe-in -138.5, 129.04 APE8-dihe-in -81.56, 62.88 APE8-rot-na 35.95 APE67-dihe-in -68.36, -15.72 -44.14, -42.79 APE12-dist-na 13.941 APE11-dist-na 10.1844 APE10-dist-na 8.9641 APE9-dist-in 6.8432 None None None AF2 -1.0 1.0 1.0 A 287.0 287.0 0 27 27 0 [[839, 1109]] 1.0 AF-P35590-K3 TYR_TIE1_HUMAN TYR 5.6e-91 310.4 1.0 259.0 259.0 996 997 998 1000 1002 870 887 891 976 978 977 979.0 1035 1023 1018 1017 1016 1015 1014 1013 1012 918 Tyrosine-protein kinase receptor Tie-1

TYR_TIE1 (Tyrosine-protein kinase receptor Tie-1)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P35590-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TIE1 TIE1_HUMAN AF-P35590-K1A P35590 831 1117 1138.0 No_ligand No_ligand Active DFGin 6.8307 14.0023 BLAminus -136.74, -177.38 58.93, 68.24 -85.88, 10.76 291.29, 88.28 -58.64, -30.14 in-in in 7.7489 Saltbr-in 2.6365 HRD-in -73.5, -44.78 67.89, -18.39 in-in-in SNCiii in-in ActLoopNT-in 2.9322 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.21, 101.49 APE9-dihe-in -132.86, 147.09 APE8-dihe-in -81.49, 82.73 APE8-rot-na 37.04 APE67-dihe-in -67.41, -15.52 -42.34, -43.57 APE12-dist-na 13.9227 APE11-dist-na 10.648 APE10-dist-na 9.259 APE9-dist-in 6.2986 None None None AF2 -1.0 1.0 1.0 A 287.0 287.0 0 27 27 0 [[839, 1109]] 1.0 AF-P35590-K1 Homo sapiens TYR_TIE1_HUMAN TYR 5.6e-91 310.4 1.0 259.0 259.0 996 997 998 1000 1002 870 887 891 976 978 977 979.0 1035 1023 1018 1017 1016 1015 1014 1013 1012 918 Tyrosine-protein kinase receptor Tie-1
TIE1 TIE1_HUMAN AF-P35590-K3A P35590 831 1117 1138.0 No_ligand No_ligand Active DFGin 6.5448 13.7855 BLAminus -139.89, -178.12 57.57, 74.65 -85.7, 11.49 292.39, 98.86 -59.99, -28.25 in-in in 7.7462 Saltbr-in 2.6682 HRD-in -75.65, -45.19 65.98, -11.15 in-in-in SNCiii in-in ActLoopNT-in 2.8828 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.64, 142.79 APE9-dihe-in -138.5, 129.04 APE8-dihe-in -81.56, 62.88 APE8-rot-na 35.95 APE67-dihe-in -68.36, -15.72 -44.14, -42.79 APE12-dist-na 13.941 APE11-dist-na 10.1844 APE10-dist-na 8.9641 APE9-dist-in 6.8432 None None None AF2 -1.0 1.0 1.0 A 287.0 287.0 0 27 27 0 [[839, 1109]] 1.0 AF-P35590-K3 Homo sapiens TYR_TIE1_HUMAN TYR 5.6e-91 310.4 1.0 259.0 259.0 996 997 998 1000 1002 870 887 891 976 978 977 979.0 1035 1023 1018 1017 1016 1015 1014 1013 1012 918 Tyrosine-protein kinase receptor Tie-1

TYR_TIE1 (Tyrosine-protein kinase receptor Tie-1)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name