CAMK_STK17B (Serine/threonine-protein kinase 17B)

Total number of chains: 12
Active chains: 2
Family: CAMK
Uniprot: ST17B_HUMAN
Kinase Domain Residues: 32 - 293
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 12 100.0% AF-O94768-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-O94768-K1A 24 301 372.0 No_ligand No_ligand Active DFGin 6.378 13.949 BLAminus -131.71, 171.68 62.89, 65.23 -80.16, 15.72 294.95, 92.5 -61.68, -26.23 in-in in 8.962 Saltbr-in 2.61 HRD-in -74.35, -40.86 62.28, 1.11 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.39, 141.06 APE9-dihe-na 119.08, -176.45 APE8-dihe-in -92.52, 130.0 APE8-rot-in 304.62 APE67-dihe-in -68.33, -14.1 -46.02, -52.27 APE12-dist-in 11.032 APE11-dist-in 12.098 APE10-dist-in 6.209 APE9-dist-in 3.858 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[32, 293]] 1.0 AF-O94768-K1 CAMK_STK17B_HUMAN CAMK 7.5e-82 280.4 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
AF-O94768-K3A 24 301 372.0 No_ligand No_ligand Active DFGin 6.035 13.873 BLAminus -132.35, 170.87 64.06, 64.13 -75.86, 13.09 295.78, 93.11 -63.33, -22.21 in-in in 8.846 Saltbr-in 2.6 HRD-in -81.95, -40.82 66.69, -5.34 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.99, 150.93 APE9-dihe-na 129.29, -168.24 APE8-dihe-in -96.41, 129.1 APE8-rot-in 303.67 APE67-dihe-in -68.22, -14.61 -46.81, -49.64 APE12-dist-in 9.258 APE11-dist-in 12.412 APE10-dist-in 6.711 APE9-dist-in 4.171 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[32, 293]] 1.0 AF-O94768-K3 CAMK_STK17B_HUMAN CAMK 7.5e-82 280.4 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
6QF4A 18 308 372.0 ADP:405 ATPlike Inactive DFGin 6.252 14.589 BLAminus -138.0, 178.42 64.68, 88.16 -110.19, 27.69 285.51, 77.31 -64.42, -20.01 out-out out 10.293 Saltbr-out 4.396 HRD-in -72.0, -51.78 71.09, 16.02 out-in-out SNCoio in-out ActLoopNT-in 3.129 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nioo APE10-dihe-na -151.1, 167.46 APE9-dihe-na 109.33, 178.09 APE8-dihe-in -61.1, 118.93 APE8-rot-in 322.5 APE67-dihe-in -69.8, -8.25 -54.96, -33.39 APE12-dist-none 999.0 APE11-dist-in 12.911 APE10-dist-out 10.081 APE9-dist-out 7.839 None None None XRAY 2.495 0.187 0.227 A 327 287 4 0 0 4 [[32, 293]] 1.0 6qf4 CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
7Q7DA 25 297 372.0 ATP:60401 ATPlike Inactive DFGin 5.979 13.981 BLAminus -131.01, 179.34 62.41, 83.11 -104.07, 20.6 289.75, 84.41 -62.74, -20.86 in-in in 9.348 Saltbr-in 3.538 HRD-in -65.32, -50.49 69.46, 8.5 in-in-out SNCiio in-out ActLoopNT-in 3.058 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -156.23, 8.1 APE9-dihe-na -82.21, -176.47 APE8-dihe-in -53.98, 115.12 APE8-rot-in 320.45 APE67-dihe-in -72.35, -13.63 -52.11, -32.33 APE12-dist-in 7.748 APE11-dist-in 12.291 APE10-dist-out 11.219 APE9-dist-out 7.597 None None None XRAY 2.6 0.196 0.235 A 327 273 0 0 0 0 [[32, 293]] 1.0 7q7d CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
7Q7EA 25 297 372.0 ATP:60401 ATPlike Inactive DFGin 5.806 13.997 BLAminus -136.48, 179.08 63.28, 89.42 -111.5, 27.32 288.43, 87.78 -70.0, -15.51 in-in in 9.313 Saltbr-in 3.117 HRD-in -75.17, -47.59 66.91, 14.25 in-in-out SNCiio in-out ActLoopNT-in 3.4 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -119.2, -9.71 APE9-dihe-na -66.55, 174.56 APE8-dihe-in -49.86, 121.22 APE8-rot-in 313.96 APE67-dihe-in -70.36, -7.82 -52.35, -34.48 APE12-dist-in 7.378 APE11-dist-in 12.111 APE10-dist-out 10.79 APE9-dist-out 7.473 None None None XRAY 2.85 0.191 0.239 A 327 273 0 0 0 0 [[32, 293]] 1.0 7q7e CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
3LM0A 25 304 372.0 EBD:60001 Type1 Inactive DFGin 6.216 14.576 BLAminus -126.94, 173.66 57.12, 80.89 -91.05, 16.39 285.69, 83.13 -58.97, -30.16 in-in in 9.77 Saltbr-in 3.451 HRD-in -65.85, -50.57 70.7, 9.65 in-in-out SNCiio in-out ActLoopNT-in 2.92 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 62.34 APE9-dihe-na -98.84, -133.32 APE8-dihe-in -74.86, 117.09 APE8-rot-in 324.99 APE67-dihe-in -72.12, -20.03 -49.9, -41.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.688 APE9-dist-out 7.535 None None None XRAY 2.35 0.206 0.267 A 327 271 9 0 0 9 [[32, 293]] 1.0 3lm0 CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
6Y6FA 25 309 372.0 OD2:60401 Type1 Inactive DFGin 6.207 14.452 BLAminus -127.24, 166.69 65.4, 83.88 -92.94, 23.99 288.71, 81.07 -58.81, -28.0 in-out in 9.959 Saltbr-out 4.643 HRD-in -73.44, -48.1 67.92, 10.6 out-in-out SNCoio in-out ActLoopNT-in 2.923 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 8.39 APE9-dihe-na -70.2, -160.17 APE8-dihe-in -77.3, 132.32 APE8-rot-in 311.84 APE67-dihe-in -63.39, -21.12 -55.03, -46.87 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.655 APE9-dist-out 6.332 None None None XRAY 1.98 0.184 0.223 A 327 276 9 0 0 9 [[32, 293]] 1.0 6y6f CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
6Y6HA 25 309 372.0 OBW:60401 Type1 Inactive DFGin 6.153 14.456 BLAminus -124.37, 165.76 70.04, 87.62 -98.4, 21.24 284.05, 84.57 -58.06, -32.09 out-out out 10.089 Saltbr-out 4.582 HRD-in -71.58, -50.5 68.06, 14.55 out-in-out SNCoio in-out ActLoopNT-in 3.013 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -135.81, 19.23 APE9-dihe-na -57.23, -179.08 APE8-dihe-in -65.09, 121.59 APE8-rot-in 325.52 APE67-dihe-in -67.35, -13.69 -45.89, -44.5 APE12-dist-in 7.692 APE11-dist-in 11.766 APE10-dist-out 9.899 APE9-dist-out 6.444 None None None XRAY 1.95 0.183 0.212 A 327 285 0 0 0 0 [[32, 293]] 1.0 6y6h CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
6ZJFA 25 309 372.0 QM2:60401 Type1 Inactive DFGin 6.14 14.343 BLAminus -127.61, 166.55 70.06, 82.09 -90.62, 21.05 287.4, 82.39 -60.71, -29.44 out-out out 10.165 Saltbr-out 4.654 HRD-in -75.81, -47.71 66.09, 10.71 out-in-out SNCoio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -118.2, 14.14 APE9-dihe-na -49.98, 178.53 APE8-dihe-in -66.77, 122.8 APE8-rot-in 306.93 APE67-dihe-in -67.95, -9.14 -50.36, -43.88 APE12-dist-in 7.946 APE11-dist-in 11.708 APE10-dist-out 9.834 APE9-dist-out 6.279 None None None XRAY 1.75 0.181 0.21 A 327 285 0 0 0 0 [[32, 293]] 1.0 6zjf CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
7AKGA 25 309 372.0 38O:60406 Type1 Inactive DFGin 5.926 14.467 BLAminus -130.72, 166.63 65.44, 83.59 -95.88, 22.94 288.63, 83.5 -68.92, -24.29 in-in in 9.846 Saltbr-in 2.802 HRD-in -68.61, -50.56 69.3, 6.9 in-in-out SNCiio in-out ActLoopNT-in 2.98 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -106.87, 75.89 APE9-dihe-na -112.61, -152.27 APE8-dihe-in -87.24, 116.8 APE8-rot-in 316.03 APE67-dihe-in -74.45, -15.03 -47.64, -40.28 APE12-dist-in 7.984 APE11-dist-in 12.31 APE10-dist-out 10.545 APE9-dist-out 6.752 None None None XRAY 2.08 0.187 0.219 A 327 285 0 0 0 0 [[32, 293]] 1.0 7akg CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
3LM5A 25 301 372.0 QUE:60001 Type1.5_Back Inactive DFGin 6.205 14.402 BLAminus -129.37, -179.21 62.69, 64.02 -84.27, 20.32 288.75, 80.24 -59.93, -27.87 in-out in 9.775 Saltbr-out 5.748 HRD-in -61.79, -47.68 66.8, 10.86 out-in-out SNCoio in-out ActLoopNT-in 2.904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 82.97 APE9-dihe-na -112.84, -148.46 APE8-dihe-in -67.19, 114.44 APE8-rot-in 309.07 APE67-dihe-in -58.89, -16.56 -51.09, -47.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.06 APE9-dist-out 7.597 None None None XRAY 2.29 0.204 0.281 A 327 267 10 0 0 9 [[32, 293]] 1.0 3lm5 CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
7Q7CA 25 297 372.0 ADP:60402 ATPlike None DFGin 5.672 13.983 BLAminus -146.28, 174.77 69.66, 80.54 -103.01, 24.61 291.62, 86.01 -65.04, -13.43 in-in in 9.403 Saltbr-in 3.35 HRD-in -84.64, -49.74 76.32, -16.47 in-in-none SNCiin in-none ActLoopNT-in 3.297 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 143.13 APE8-rot-in 309.53 APE67-dihe-in -65.37, -16.14 -54.33, -43.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.85 0.21 0.238 A 327 265 8 0 0 8 [[32, 293]] 1.0 7q7c CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B

CAMK_STK17B (Serine/threonine-protein kinase 17B)

Total number of chains: 12
Active chains: 2
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 12 100.0% AF-O94768-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
ST17B_HUMAN AF-O94768-K1A O94768 24 301 372.0 No_ligand No_ligand Active DFGin 6.378 13.949 BLAminus -131.71, 171.68 62.89, 65.23 -80.16, 15.72 294.95, 92.5 -61.68, -26.23 in-in in 8.962 Saltbr-in 2.61 HRD-in -74.35, -40.86 62.28, 1.11 in-in-in SNCiii in-in ActLoopNT-in 2.942 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.39, 141.06 APE9-dihe-na 119.08, -176.45 APE8-dihe-in -92.52, 130.0 APE8-rot-in 304.62 APE67-dihe-in -68.33, -14.1 -46.02, -52.27 APE12-dist-in 11.032 APE11-dist-in 12.098 APE10-dist-in 6.209 APE9-dist-in 3.858 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[32, 293]] 1.0 AF-O94768-K1 Homo sapiens CAMK_STK17B_HUMAN CAMK 7.5e-82 280.4 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN AF-O94768-K3A O94768 24 301 372.0 No_ligand No_ligand Active DFGin 6.035 13.873 BLAminus -132.35, 170.87 64.06, 64.13 -75.86, 13.09 295.78, 93.11 -63.33, -22.21 in-in in 8.846 Saltbr-in 2.6 HRD-in -81.95, -40.82 66.69, -5.34 in-in-in SNCiii in-in ActLoopNT-in 2.934 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -150.99, 150.93 APE9-dihe-na 129.29, -168.24 APE8-dihe-in -96.41, 129.1 APE8-rot-in 303.67 APE67-dihe-in -68.22, -14.61 -46.81, -49.64 APE12-dist-in 9.258 APE11-dist-in 12.412 APE10-dist-in 6.711 APE9-dist-in 4.171 None None None AF2 -1.0 1.0 1.0 A 278 278 0 0 0 0 [[32, 293]] 1.0 AF-O94768-K3 Homo sapiens CAMK_STK17B_HUMAN CAMK 7.5e-82 280.4 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 6QF4A O94768 18 308 372.0 ADP:405 ATPlike Inactive DFGin 6.252 14.589 BLAminus -138.0, 178.42 64.68, 88.16 -110.19, 27.69 285.51, 77.31 -64.42, -20.01 out-out out 10.293 Saltbr-out 4.396 HRD-in -72.0, -51.78 71.09, 16.02 out-in-out SNCoio in-out ActLoopNT-in 3.129 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nioo APE10-dihe-na -151.1, 167.46 APE9-dihe-na 109.33, 178.09 APE8-dihe-in -61.1, 118.93 APE8-rot-in 322.5 APE67-dihe-in -69.8, -8.25 -54.96, -33.39 APE12-dist-none 999.0 APE11-dist-in 12.911 APE10-dist-out 10.081 APE9-dist-out 7.839 None None None XRAY 2.495 0.187 0.227 A 327 287 4 0 0 4 [[32, 293]] 1.0 6qf4 Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 7Q7DA O94768 25 297 372.0 ATP:60401 ATPlike Inactive DFGin 5.979 13.981 BLAminus -131.01, 179.34 62.41, 83.11 -104.07, 20.6 289.75, 84.41 -62.74, -20.86 in-in in 9.348 Saltbr-in 3.538 HRD-in -65.32, -50.49 69.46, 8.5 in-in-out SNCiio in-out ActLoopNT-in 3.058 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -156.23, 8.1 APE9-dihe-na -82.21, -176.47 APE8-dihe-in -53.98, 115.12 APE8-rot-in 320.45 APE67-dihe-in -72.35, -13.63 -52.11, -32.33 APE12-dist-in 7.748 APE11-dist-in 12.291 APE10-dist-out 11.219 APE9-dist-out 7.597 None None None XRAY 2.6 0.196 0.235 A 327 273 0 0 0 0 [[32, 293]] 1.0 7q7d Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 7Q7EA O94768 25 297 372.0 ATP:60401 ATPlike Inactive DFGin 5.806 13.997 BLAminus -136.48, 179.08 63.28, 89.42 -111.5, 27.32 288.43, 87.78 -70.0, -15.51 in-in in 9.313 Saltbr-in 3.117 HRD-in -75.17, -47.59 66.91, 14.25 in-in-out SNCiio in-out ActLoopNT-in 3.4 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -119.2, -9.71 APE9-dihe-na -66.55, 174.56 APE8-dihe-in -49.86, 121.22 APE8-rot-in 313.96 APE67-dihe-in -70.36, -7.82 -52.35, -34.48 APE12-dist-in 7.378 APE11-dist-in 12.111 APE10-dist-out 10.79 APE9-dist-out 7.473 None None None XRAY 2.85 0.191 0.239 A 327 273 0 0 0 0 [[32, 293]] 1.0 7q7e Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 3LM0A O94768 25 304 372.0 EBD:60001 Type1 Inactive DFGin 6.216 14.576 BLAminus -126.94, 173.66 57.12, 80.89 -91.05, 16.39 285.69, 83.13 -58.97, -30.16 in-in in 9.77 Saltbr-in 3.451 HRD-in -65.85, -50.57 70.7, 9.65 in-in-out SNCiio in-out ActLoopNT-in 2.92 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 62.34 APE9-dihe-na -98.84, -133.32 APE8-dihe-in -74.86, 117.09 APE8-rot-in 324.99 APE67-dihe-in -72.12, -20.03 -49.9, -41.85 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 11.688 APE9-dist-out 7.535 None None None XRAY 2.35 0.206 0.267 A 327 271 9 0 0 9 [[32, 293]] 1.0 3lm0 Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 6Y6FA O94768 25 309 372.0 OD2:60401 Type1 Inactive DFGin 6.207 14.452 BLAminus -127.24, 166.69 65.4, 83.88 -92.94, 23.99 288.71, 81.07 -58.81, -28.0 in-out in 9.959 Saltbr-out 4.643 HRD-in -73.44, -48.1 67.92, 10.6 out-in-out SNCoio in-out ActLoopNT-in 2.923 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 8.39 APE9-dihe-na -70.2, -160.17 APE8-dihe-in -77.3, 132.32 APE8-rot-in 311.84 APE67-dihe-in -63.39, -21.12 -55.03, -46.87 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 9.655 APE9-dist-out 6.332 None None None XRAY 1.98 0.184 0.223 A 327 276 9 0 0 9 [[32, 293]] 1.0 6y6f Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 6Y6HA O94768 25 309 372.0 OBW:60401 Type1 Inactive DFGin 6.153 14.456 BLAminus -124.37, 165.76 70.04, 87.62 -98.4, 21.24 284.05, 84.57 -58.06, -32.09 out-out out 10.089 Saltbr-out 4.582 HRD-in -71.58, -50.5 68.06, 14.55 out-in-out SNCoio in-out ActLoopNT-in 3.013 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -135.81, 19.23 APE9-dihe-na -57.23, -179.08 APE8-dihe-in -65.09, 121.59 APE8-rot-in 325.52 APE67-dihe-in -67.35, -13.69 -45.89, -44.5 APE12-dist-in 7.692 APE11-dist-in 11.766 APE10-dist-out 9.899 APE9-dist-out 6.444 None None None XRAY 1.95 0.183 0.212 A 327 285 0 0 0 0 [[32, 293]] 1.0 6y6h Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 6ZJFA O94768 25 309 372.0 QM2:60401 Type1 Inactive DFGin 6.14 14.343 BLAminus -127.61, 166.55 70.06, 82.09 -90.62, 21.05 287.4, 82.39 -60.71, -29.44 out-out out 10.165 Saltbr-out 4.654 HRD-in -75.81, -47.71 66.09, 10.71 out-in-out SNCoio in-out ActLoopNT-in 2.9 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -118.2, 14.14 APE9-dihe-na -49.98, 178.53 APE8-dihe-in -66.77, 122.8 APE8-rot-in 306.93 APE67-dihe-in -67.95, -9.14 -50.36, -43.88 APE12-dist-in 7.946 APE11-dist-in 11.708 APE10-dist-out 9.834 APE9-dist-out 6.279 None None None XRAY 1.75 0.181 0.21 A 327 285 0 0 0 0 [[32, 293]] 1.0 6zjf Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 7AKGA O94768 25 309 372.0 38O:60406 Type1 Inactive DFGin 5.926 14.467 BLAminus -130.72, 166.63 65.44, 83.59 -95.88, 22.94 288.63, 83.5 -68.92, -24.29 in-in in 9.846 Saltbr-in 2.802 HRD-in -68.61, -50.56 69.3, 6.9 in-in-out SNCiio in-out ActLoopNT-in 2.98 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioo APE10-dihe-na -106.87, 75.89 APE9-dihe-na -112.61, -152.27 APE8-dihe-in -87.24, 116.8 APE8-rot-in 316.03 APE67-dihe-in -74.45, -15.03 -47.64, -40.28 APE12-dist-in 7.984 APE11-dist-in 12.31 APE10-dist-out 10.545 APE9-dist-out 6.752 None None None XRAY 2.08 0.187 0.219 A 327 285 0 0 0 0 [[32, 293]] 1.0 7akg Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 3LM5A O94768 25 301 372.0 QUE:60001 Type1.5_Back Inactive DFGin 6.205 14.402 BLAminus -129.37, -179.21 62.69, 64.02 -84.27, 20.32 288.75, 80.24 -59.93, -27.87 in-out in 9.775 Saltbr-out 5.748 HRD-in -61.79, -47.68 66.8, 10.86 out-in-out SNCoio in-out ActLoopNT-in 2.904 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 82.97 APE9-dihe-na -112.84, -148.46 APE8-dihe-in -67.19, 114.44 APE8-rot-in 309.07 APE67-dihe-in -58.89, -16.56 -51.09, -47.49 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.06 APE9-dist-out 7.597 None None None XRAY 2.29 0.204 0.281 A 327 267 10 0 0 9 [[32, 293]] 1.0 3lm5 Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B
ST17B_HUMAN 7Q7CA O94768 25 297 372.0 ADP:60402 ATPlike None DFGin 5.672 13.983 BLAminus -146.28, 174.77 69.66, 80.54 -103.01, 24.61 291.62, 86.01 -65.04, -13.43 in-in in 9.403 Saltbr-in 3.35 HRD-in -84.64, -49.74 76.32, -16.47 in-in-none SNCiin in-none ActLoopNT-in 3.297 ActLoopCT-none nonTYR APEdihe_aanii APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 143.13 APE8-rot-in 309.53 APE67-dihe-in -65.37, -16.14 -54.33, -43.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.85 0.21 0.238 A 327 265 8 0 0 8 [[32, 293]] 1.0 7q7c Homo sapiens CAMK_STK17B_HUMAN CAMK 1.4e-81 279.8 4 256 253 178 179 180 182 184 62 80 84 155 157 156 158 217 205 200 199 198 197 196 195 194 111 Serine/threonine-protein kinase 17B

CAMK_STK17B (Serine/threonine-protein kinase 17B)

Total number of chains: 0
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name