CAMK_SPEG-2 (Striated muscle preferentially expressed protein kinase)

Total number of chains: 2
Active chains: 2
Family: CAMK
Uniprot: SPEG_HUMAN
Kinase Domain Residues: 2966 - 3218
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q15772-K2A

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PDB First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AF-Q15772-K2A 2958 3226 3267.0 No_ligand No_ligand Active DFGin 6.704 13.53 BLAminus -123.37, 171.71 58.4, 85.56 -91.05, 20.13 285.74, 77.72 -64.09, -25.88 in-in in 8.189 Saltbr-in 2.66 HRD-in -81.22, -44.79 65.23, 4.7 in-in-in SNCiii in-in ActLoopNT-in 2.853 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.62, 170.75 APE9-dihe-na 75.36, -171.05 APE8-dihe-in -95.47, 124.93 APE8-rot-in 296.37 APE67-dihe-in -55.39, -27.99 -51.12, -47.01 APE12-dist-in 10.321 APE11-dist-in 10.889 APE10-dist-in 5.014 APE9-dist-in 4.253 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[1601, 1854], [2966, 3218]] 2.0 AF-Q15772-K2 CAMK_SPEG-2_HUMAN CAMK 3.4e-70 242.2 1 256 256 3102 3103 3104 3106 3108 2995 3010 3014 3082 3084 3083 3085 3143 3131 3126 3125 3124 3123 3122 3121 3120 3040 Striated muscle preferentially expressed protein kinase
AF-Q15772-K4A 2958 3226 3267.0 No_ligand No_ligand Active DFGin 6.464 13.572 BLAminus -129.62, 174.0 53.57, 88.0 -90.65, 18.21 285.96, 79.38 -63.76, -19.69 in-in in 8.119 Saltbr-in 2.696 HRD-in -83.33, -44.04 65.09, 7.54 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.98, 165.73 APE9-dihe-na 72.61, -163.33 APE8-dihe-in -108.75, 125.58 APE8-rot-in 309.64 APE67-dihe-in -56.2, -27.05 -49.46, -48.42 APE12-dist-in 10.218 APE11-dist-in 10.372 APE10-dist-in 4.707 APE9-dist-in 3.601 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[1601, 1854], [2966, 3218]] 2.0 AF-Q15772-K4 CAMK_SPEG-2_HUMAN CAMK 3.4e-70 242.2 1 256 256 3102 3103 3104 3106 3108 2995 3010 3014 3082 3084 3083 3085 3143 3131 3126 3125 3124 3123 3122 3121 3120 3040 Striated muscle preferentially expressed protein kinase

CAMK_SPEG-2 (Striated muscle preferentially expressed protein kinase)

Total number of chains: 2
Active chains: 2
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q15772-K2A

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
SPEG_HUMAN AF-Q15772-K2A Q15772 2958 3226 3267.0 No_ligand No_ligand Active DFGin 6.704 13.53 BLAminus -123.37, 171.71 58.4, 85.56 -91.05, 20.13 285.74, 77.72 -64.09, -25.88 in-in in 8.189 Saltbr-in 2.66 HRD-in -81.22, -44.79 65.23, 4.7 in-in-in SNCiii in-in ActLoopNT-in 2.853 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.62, 170.75 APE9-dihe-na 75.36, -171.05 APE8-dihe-in -95.47, 124.93 APE8-rot-in 296.37 APE67-dihe-in -55.39, -27.99 -51.12, -47.01 APE12-dist-in 10.321 APE11-dist-in 10.889 APE10-dist-in 5.014 APE9-dist-in 4.253 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[1601, 1854], [2966, 3218]] 2.0 AF-Q15772-K2 Homo sapiens CAMK_SPEG-2_HUMAN CAMK 3.4e-70 242.2 1 256 256 3102 3103 3104 3106 3108 2995 3010 3014 3082 3084 3083 3085 3143 3131 3126 3125 3124 3123 3122 3121 3120 3040 Striated muscle preferentially expressed protein kinase
SPEG_HUMAN AF-Q15772-K4A Q15772 2958 3226 3267.0 No_ligand No_ligand Active DFGin 6.464 13.572 BLAminus -129.62, 174.0 53.57, 88.0 -90.65, 18.21 285.96, 79.38 -63.76, -19.69 in-in in 8.119 Saltbr-in 2.696 HRD-in -83.33, -44.04 65.09, 7.54 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.98, 165.73 APE9-dihe-na 72.61, -163.33 APE8-dihe-in -108.75, 125.58 APE8-rot-in 309.64 APE67-dihe-in -56.2, -27.05 -49.46, -48.42 APE12-dist-in 10.218 APE11-dist-in 10.372 APE10-dist-in 4.707 APE9-dist-in 3.601 None None None AF2 -1.0 1.0 1.0 A 269 269 0 0 0 0 [[1601, 1854], [2966, 3218]] 2.0 AF-Q15772-K4 Homo sapiens CAMK_SPEG-2_HUMAN CAMK 3.4e-70 242.2 1 256 256 3102 3103 3104 3106 3108 2995 3010 3014 3082 3084 3083 3085 3143 3131 3126 3125 3124 3123 3122 3121 3120 3040 Striated muscle preferentially expressed protein kinase

CAMK_SPEG-2 (Striated muscle preferentially expressed protein kinase)

Total number of chains: 0
Active chains: 0
Family: CAMK
Spatial label Dihedral label Number of Chains Percent Representative

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SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name