CAMK_SIK2 (Serine/threonine-protein kinase SIK2)

Total number of chains: 2
Active chains: 2
Uniprot: SIK2_HUMAN
Kinase Domain Residues: 20 - 271
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9H0K1-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
SIK2 AF-Q9H0K1-K1A Q9H0K1 12 279 926.0 No_ligand No_ligand Active DFGin 6.7943 14.904 BLAminus -119.71, 175.68 54.99, 79.06 -86.38, 20.59 287.67, 84.31 -58.82, -32.81 in-in in 9.1831 Saltbr-in 2.6891 HRD-in -84.35, -44.78 62.69, 9.43 in-in-in SNCiii in-in ActLoopNT-in 2.9168 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.86, 159.69 APE9-dihe-na 95.61, 178.37 APE8-dihe-in -87.35, 128.5 APE8-rot-in 305.13 APE67-dihe-in -66.65, -20.4 -49.85, -40.76 APE12-dist-in 8.7002 APE11-dist-in 10.9882 APE10-dist-in 5.2211 APE9-dist-in 3.3397 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 27 27 0 [[20, 271]] 1.0 AF-Q9H0K1-K1 CAMK_SIK2_HUMAN CAMK 9.2e-96 326.0 1.0 256.0 256.0 159 160 161 163 165 49 67 71 139 141 140 142.0 199 186 181 180 179 178 177 176 175 97 Serine/threonine-protein kinase SIK2
SIK2 AF-Q9H0K1-K3A Q9H0K1 12 279 926.0 No_ligand No_ligand Active DFGin 6.4001 14.6744 BLAminus -127.01, 171.99 54.96, 76.72 -80.3, 21.97 290.31, 82.18 -59.59, -27.04 in-in in 9.1227 Saltbr-in 2.7334 HRD-in -83.51, -43.49 65.09, -3.92 in-in-in SNCiii in-in ActLoopNT-in 2.9114 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.44, 167.61 APE9-dihe-na 125.35, 164.53 APE8-dihe-in -76.88, 124.81 APE8-rot-in 299.49 APE67-dihe-in -67.89, -17.07 -50.55, -40.34 APE12-dist-in 8.3296 APE11-dist-in 11.1779 APE10-dist-in 5.7023 APE9-dist-in 3.5272 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 27 27 0 [[20, 271]] 1.0 AF-Q9H0K1-K3 CAMK_SIK2_HUMAN CAMK 9.2e-96 326.0 1.0 256.0 256.0 159 160 161 163 165 49 67 71 139 141 140 142.0 199 186 181 180 179 178 177 176 175 97 Serine/threonine-protein kinase SIK2

CAMK_SIK2 (Serine/threonine-protein kinase SIK2)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-Q9H0K1-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
SIK2 SIK2_HUMAN AF-Q9H0K1-K1A Q9H0K1 12 279 926.0 No_ligand No_ligand Active DFGin 6.7943 14.904 BLAminus -119.71, 175.68 54.99, 79.06 -86.38, 20.59 287.67, 84.31 -58.82, -32.81 in-in in 9.1831 Saltbr-in 2.6891 HRD-in -84.35, -44.78 62.69, 9.43 in-in-in SNCiii in-in ActLoopNT-in 2.9168 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -144.86, 159.69 APE9-dihe-na 95.61, 178.37 APE8-dihe-in -87.35, 128.5 APE8-rot-in 305.13 APE67-dihe-in -66.65, -20.4 -49.85, -40.76 APE12-dist-in 8.7002 APE11-dist-in 10.9882 APE10-dist-in 5.2211 APE9-dist-in 3.3397 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 27 27 0 [[20, 271]] 1.0 AF-Q9H0K1-K1 Homo sapiens CAMK_SIK2_HUMAN CAMK 9.2e-96 326.0 1.0 256.0 256.0 159 160 161 163 165 49 67 71 139 141 140 142.0 199 186 181 180 179 178 177 176 175 97 Serine/threonine-protein kinase SIK2
SIK2 SIK2_HUMAN AF-Q9H0K1-K3A Q9H0K1 12 279 926.0 No_ligand No_ligand Active DFGin 6.4001 14.6744 BLAminus -127.01, 171.99 54.96, 76.72 -80.3, 21.97 290.31, 82.18 -59.59, -27.04 in-in in 9.1227 Saltbr-in 2.7334 HRD-in -83.51, -43.49 65.09, -3.92 in-in-in SNCiii in-in ActLoopNT-in 2.9114 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -148.44, 167.61 APE9-dihe-na 125.35, 164.53 APE8-dihe-in -76.88, 124.81 APE8-rot-in 299.49 APE67-dihe-in -67.89, -17.07 -50.55, -40.34 APE12-dist-in 8.3296 APE11-dist-in 11.1779 APE10-dist-in 5.7023 APE9-dist-in 3.5272 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 27 27 0 [[20, 271]] 1.0 AF-Q9H0K1-K3 Homo sapiens CAMK_SIK2_HUMAN CAMK 9.2e-96 326.0 1.0 256.0 256.0 159 160 161 163 165 49 67 71 139 141 140 142.0 199 186 181 180 179 178 177 176 175 97 Serine/threonine-protein kinase SIK2

CAMK_SIK2 (Serine/threonine-protein kinase SIK2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name