CAMK_RPS6KA4-2 (Ribosomal protein S6 kinase alpha-4)

Total number of chains: 2
Active chains: 2
Uniprot: KS6A4_HUMAN
Kinase Domain Residues: 408 - 674
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O75676-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA4-2 AF-O75676-K2A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.6249 13.9757 BLAminus -120.67, 178.37 58.42, 72.08 -82.57, 18.56 283.59, 66.24 -61.05, -28.33 in-in in 8.6277 Saltbr-in 2.7131 HRD-in -75.59, -46.6 67.67, -1.45 in-in-in SNCiii in-in ActLoopNT-in 2.8025 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.5, 118.13 APE9-dihe-na -165.28, 159.12 APE8-dihe-in -96.39, 123.29 APE8-rot-in 303.72 APE67-dihe-in -63.09, -21.71 -49.19, -44.65 APE12-dist-in 8.9613 APE11-dist-in 10.8303 APE10-dist-in 5.0107 APE9-dist-in 4.1447 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K2 CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5.0 256.0 252.0 550 551 552 554 556 440 453 457 527 529 528 530.0 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4
RPS6KA4-2 AF-O75676-K4A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.176 14.0199 BLAminus -122.38, 175.76 59.23, 72.02 -80.76, 17.2 284.29, 67.3 -58.65, -30.45 in-in in 8.5379 Saltbr-in 2.6836 HRD-in -77.81, -45.53 69.45, -2.15 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.24, 117.86 APE9-dihe-na -166.45, 155.97 APE8-dihe-in -91.4, 121.79 APE8-rot-in 302.05 APE67-dihe-in -66.49, -20.11 -51.14, -42.05 APE12-dist-in 8.5102 APE11-dist-in 11.1284 APE10-dist-in 5.1507 APE9-dist-in 4.2022 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K4 CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5.0 256.0 252.0 550 551 552 554 556 440 453 457 527 529 528 530.0 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4

CAMK_RPS6KA4-2 (Ribosomal protein S6 kinase alpha-4)

Total number of chains: 2
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O75676-K2A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
RPS6KA4-2 KS6A4_HUMAN AF-O75676-K2A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.6249 13.9757 BLAminus -120.67, 178.37 58.42, 72.08 -82.57, 18.56 283.59, 66.24 -61.05, -28.33 in-in in 8.6277 Saltbr-in 2.7131 HRD-in -75.59, -46.6 67.67, -1.45 in-in-in SNCiii in-in ActLoopNT-in 2.8025 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.5, 118.13 APE9-dihe-na -165.28, 159.12 APE8-dihe-in -96.39, 123.29 APE8-rot-in 303.72 APE67-dihe-in -63.09, -21.71 -49.19, -44.65 APE12-dist-in 8.9613 APE11-dist-in 10.8303 APE10-dist-in 5.0107 APE9-dist-in 4.1447 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K2 Homo sapiens CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5.0 256.0 252.0 550 551 552 554 556 440 453 457 527 529 528 530.0 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4
RPS6KA4-2 KS6A4_HUMAN AF-O75676-K4A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.176 14.0199 BLAminus -122.38, 175.76 59.23, 72.02 -80.76, 17.2 284.29, 67.3 -58.65, -30.45 in-in in 8.5379 Saltbr-in 2.6836 HRD-in -77.81, -45.53 69.45, -2.15 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.24, 117.86 APE9-dihe-na -166.45, 155.97 APE8-dihe-in -91.4, 121.79 APE8-rot-in 302.05 APE67-dihe-in -66.49, -20.11 -51.14, -42.05 APE12-dist-in 8.5102 APE11-dist-in 11.1284 APE10-dist-in 5.1507 APE9-dist-in 4.2022 None None None AF2 -1.0 1.0 1.0 A 283.0 283.0 0 29 29 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K4 Homo sapiens CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5.0 256.0 252.0 550 551 552 554 556 440 453 457 527 529 528 530.0 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4

CAMK_RPS6KA4-2 (Ribosomal protein S6 kinase alpha-4)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name